784 research outputs found

    How sensorimotor interaction shapes and supports young children's gestural communication around science

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    Research has demonstrated that gesture produced during conversation can provide insights into scientific thinking and can aid scientific communication in adults and school-aged children. However, to date, there has been a limited exploration into the role of gesture in supporting young children’s science communication, and how this is underpinned and shaped by their sensorimotor experiences. This study examines, identifies and conceptualises ways in which children spontaneously used gesture during their interaction-orientated discourse and how this mapped to their action experiences at a water table. Findings show how gestural communication in children under 5 years of age can convey different levels of complexity related to science thinking

    Araldite as an Embedding Medium for Electron Microscopy

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    The origin of Jupiter's outer radiation belt

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    The intense inner radiation belt at Jupiter (>50 MeV at 1.5 RJ) is generally accepted to be created by radial diffusion of electrons from further away from the planet. However, this requires a source with energies that exceed 1 MeV outside the orbit of the moon Io at 5.9 RJ, which has never been explained satisfactorily. Here we test the hypothesis that this source population could be formed from a very soft energy spectrum, by particle injection processes and resonant electron acceleration via whistler mode chorus waves. We use the British Antarctic Survey Radiation Belt Model to calculate the change in the electron flux between 6.5 and 15 RJ; these are the first simulations at Jupiter combining wave particle interactions and radial diffusion. The resulting electron flux at 100 keV and 1 MeV lies very close to the Galileo Interim Radiation Electron model spectrum after 1 and 10 days, respectively. The primary driver for the increase in the flux is cyclotron resonant acceleration by chorus waves. A peak in phase space density forms such that inside L≈9 radial diffusion transports electrons toward Jupiter, but outside L≈9 radial diffusion acts away from the planet. The results are insensitive to the softness of the initial energy spectrum but do depend on the value of the flux at the minimum energy boundary. We conclude by suggesting that the source population for the inner radiation belt at Jupiter could indeed be formed by wave-particle interactions

    Chorus acceleration of radiation belt relativistic electrons during March 2013 geomagnetic storm

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    Abstract The recent launching of Van Allen probes provides an unprecedent opportunity to investigate variations of the radiation belt relativistic electrons. During the 17-19 March 2013 storm, the Van Allen probes simultaneously detected strong chorus waves and substantial increases in fluxes of relativistic (2 - 4.5 MeV) electrons around L = 4.5. Chorus waves occurred within the lower band 0.1-0.5fce (theelectron equatorial gyrofrequency), with a peak spectral density ∼10-4 nT 2/Hz. Correspondingly, relativistic electron fluxes increased by a factor of 102-103 during the recovery phase compared to the main phase levels. By means of a Gaussian fit to the observed chorus spectra, the drift and bounce-averaged diffusion coefficients are calculated and then used to solve a 2-D Fokker-Planck diffusion equation. Numerical simulations demonstrate that the lower-band chorus waves indeed produce such huge enhancements in relativistic electron fluxes within 15 h, fitting well with the observation. Key Points Initial RBSP correlated data of chorus waves and relativistic electron fluxes A realistic simulation to examine effect of chorus on relativistic electron flux Chorus yields huge increases inelectron flux rapidly, consistent with data

    Effect of Cigarette Smoke Exposure and Mutant Kras Overexpression on Pancreatic Cell Proliferation

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    Pancreatic cancer is the fourth leading cause of cancer‑associated mortality. The major risk factor for pancreatic cancer is cigarette smoking. Kras mutations are commonly observed in human pancreatic cancers. The present study examined the hypothesis that exposure to cigarette smoke and overexpression of a mutant Kras gene in the pancreas affects pancreatic cell proliferation in mice. Mice overexpressing the mutant Kras gene (KRasG12D) in the pancreas as well as wild‑type mice were exposed to environmental tobacco smoke for 2 weeks. Overexpression of mutant Kras increased cell proliferation in pancreatic ductal, acinar and islet cells. Notably, cigarette smoke exposure decreased cell proliferation in pancreatic ductal and acinar cells, and had no effect in islet cells. Cigarette smoke did not affect pancreatic protein levels of tumor necrosis factor (TNF)α, p53, or cyclin D1, but mutant Kras overexpression slightly decreased TNFα and p53 protein levels. Therefore, pancreatic cell proliferation in mice overexpressing mutant Kras is associated with the later development of pancreatic tumors, but effects of cigarette smoke on pancreatic cell proliferation do not provide a good model for human pancreatic carcinogenesis

    Minimum Induced Drag for Tapered Wings Including Structural Constraints

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    For a wing in steady level flight, the lift distribution that minimizes induced drag depends on a tradeoff between wingspan and wing-structure weight. In 1933, Prandtl suggested that tapered wings have an advantage over rectangular wings due to this tradeoff. However, Prandtl’s solutions were obtained using assumptions that correspond to rectangular wings. Therefore, his claim was not analytically proven by his 1933 publication. Here, an approach similar to Prandtl’s is taken with more general approximations that apply to wings of arbitrary planform. This more general development is used to study Prandtl’s claim about tapered wings. Closed-form solutions for the optimum wingspan and corresponding induced drag are presented for wings having elliptic and linearly-tapered planforms with constraints of fixed wing loading and maximum stress. It is shown that induced drag is minimized with a triangular planform, which gives a reduction in induced drag of up to 24.44% over the rectangular planform and up to 11.71% over the elliptic planform. Numerical solutions for the lift distributions that minimize induced drag for each planform are also presented. It is shown that the optimum lift distribution produces up to 5.94% less induced drag than the elliptic lift distribution when the triangular planform is used

    Electron acceleration at Jupiter: input from cyclotron-resonant interaction with whistler-mode chorus waves

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    Jupiter has the most intense radiation belts of all the outer planets. It is not yet known how electrons can be accelerated to energies of 10 MeV or more. It has been suggested that cyclotron-resonant wave-particle interactions by chorus waves could accelerate electrons to a few MeV near the orbit of Io. Here we use the chorus wave intensities observed by the Galileo spacecraft to calculate the changes in electron flux as a result of pitch angle and energy diffusion. We show that, when the bandwidth of the waves and its variation with L are taken into account, pitch angle and energy diffusion due to chorus waves is a factor of 8 larger at L-shells greater than 10 than previously shown. We have used the latitudinal wave intensity profile from Galileo data to model the time evolution of the electron flux using the British Antarctic Survey Radiation Belt (BAS) model. This profile confines intense chorus waves near the magnetic equator with a peak intensity at ∼5° latitude. Electron fluxes in the BAS model increase by an order of magnitude for energies around 3 MeV. Extending our results to L = 14 shows that cyclotron-resonant interactions with chorus waves are equally important for electron acceleration beyond L = 10. These results suggest that there is significant electron acceleration by cyclotron-resonant interactions at Jupiter contributing to the creation of Jupiter's radiation belts and also increasing the range of L-shells over which this mechanism should be considered

    Oscillatory oblique stagnation-point flow toward a plane wall

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    Two-dimensional oscillatory oblique stagnation-point flow toward a plane wall is investigated. The problem is a eneralisation of the steady oblique stagnation-point flow examined by previous workers. Far from the wall, the flow is composed of an irrotational orthogonal stagnation-point flow with a time-periodic strength, a simple shear flow of constant vorticity, and a time-periodic uniform stream. An exact solution of the Navier-Stokes equations is sought for which the flow streamfunction depends linearly on the coordinate parallel to the wall. The problem formulation reduces to a coupled pair of partial differential equations in time and one spatial variable. The first equation describes the oscillatory orthogonal stagnation-point flow discussed by previous workers. The second equation, which couples to the first, describes the oblique component of the flow. A description of the flow velocity field, the instantaneous streamlines, and the particle paths is sought through numerical solutions of the governing equations and via asymptotic analysis
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