The StEllar Counterparts of COmpact high velocity clouds (SECCO) survey. II. Sensitivity of the survey and an Atlas of Synthetic Dwarf Galaxies

SECCO is a survey devoted to the search for stellar counterparts within Ultra Compact High Velocity Clouds. In this contribution we present the results of a set of simulations aimed at the quantitative estimate of the sensitivity of the survey as a function of the total luminosity, size and distance of the stellar systems we are looking for. For all our synthetic galaxies we assumed an exponential surface brightness profile and an old and metal-poor population. The synthetic galaxies are simulated both on the images and on the photometric catalogs, taking into account all the observational effects. In the fields where the available observational material is of the top quality we detect synthetic galaxies as >=5 sigma over-densities of resolved stars down to muV,h=30.0 mag/arcsec2, for D<=1.5 Mpc, and down to muV,h~29.5 mag/arcsec2, for D<=2.5 Mpc. In the field with the worst observational material of the whole survey we detect synthetic galaxies with muV,h<=28.8 mag/arcsec2 out to D<=1.0 Mpc, and those with muV,h<=27.5 mag/arcsec2 out to D<=2.5 Mpc. Dwarf galaxies with MV=-10, with sizes in the range spanned by known dwarfs, are detected by visual inspection of the images up to D=5 Mpc independently of the image quality. In the best quality images dwarfs are partially resolved into stars up to D=3.0 Mpc, and completely unresolved at D=5 Mpc. As an independent test of the sensitivity of our images to low surface brightness galaxies we report on the detection of several dwarf spheroidal galaxies probably located in the Virgo cluster with MV<=-8.0 and muV,h<=26.8 mag/arcsec2. The nature of the previously discovered SECCO 1 stellar system, also likely located in the Virgo cluster, is re-discussed in comparison with these dwarfs. While specific for the SECCO survey, our study may also provide general guidelines for detection of faint stellar systems with 8m class telescopes.Comment: accepted for publication on A&

Combining Multiple Measures of Students' Opportunities to Develop Analytic, Text-Based Writing Skills

Guided by evidence that teachers contribute to student achievement outcomes, researchers have been reexamining how to study instruction and the classroom opportunities teachers create for students. We describe our experience measuring students' opportunities to develop analytic, text-based writing skills. Utilizing multiple methods of data collection-writing assignment tasks, daily logs, and an annual survey-we generated a composite that was used in prediction models to examine multivariate outcomes, including scores on a state accountability test and a project-developed response-to-text assessment. Our findings demonstrate that students' opportunities to develop analytic, text-based writing skills predicted classroom performance on the project-developed response-to-text assessment. We discuss the importance of considering the measure(s) of learning when examining teaching-learning associations as well as implications for combining multiple measures for purposes of better construct representation. © 2012 Copyright Taylor and Francis Group, LLC

Assessing students' skills at writing analytically in response to texts

Despite the importance of writing analytically in response to texts, there are few assessments measuring students' mastery of this skill. This manuscript describes the development of a response-to-text assessment (RTA) intended for use in research. In a subsequent validity investigation we examined whether the RTA distinguished among classrooms in students' ability to write analytically in response to text and whether measures of teaching predicted this variation. We demonstrate that the RTA was correlated with the state standardized assessment, but did not overlap with this accountability test completely and, additionally, that more variation between classrooms existed on the RTA. Students' opportunities for reasoning and extended writing in the classroom were significantly associated with RTA scores. The findings suggest that the RTA can be a valuable tool for conducting research on students' attainment of analytic writing skills and for understanding how teaching relates to student achievement on these skills. © 2013 by The University of Chicago. All rights reserved

Investigating the effectiveness of a comprehensive literacy coaching program in schools with high teacher mobility

Teacher mobility is a factor that impacts schoolwide implementation of professional development programs. In this article, we present interim results of a longitudinal randomized field trial of a comprehensive literacy coaching program (Content-Focused Coaching, CFC) for improving instruction and learning in schools with high teacher mobility.Weinvestigate program effects on 73 new treatment and comparison teachers recruited to replace the large proportion of teachers who left their schools during the first year of the program. HLM analyses indicated that the CFC program predicted significantly higher school-level gains on the state standardized test for English language learners (N=496, ES=.51). By spring, the quality of teachers' self-reported and observed instruction in the CFC schools exceeded that of comparison teachers. Implications for accommodating new teachers into an ongoing and established coaching program to improve instruction and student learning, and conducting randomized trials in schools with high teacher turnover, are discussed. Copyright © 2010 by The University of Chicago

The quality of writing tasks and students' use of academic language in Spanish

This study investigates the quality of the writing tasks assigned to native Spanish speakers in bilingual (Spanish-English) contexts, and the relationship between task quality and students' use of an academic register in their native language. Fifty-six language arts tasks were collected from 26 grade 4 and 5 teachers, and four student writing samples were collected in response to each task (N = 224). Multilevel modeling revealed that variation in students' use of key features of academic language in their writing was associated with the cognitive demand of writing tasks. Findings suggest that students' opportunities to respond to challenging tasks when writing in their native language are rare and that the rigor of writing tasks may relate to students' production and development of academic language. © 2012 by The University of Chicago. All rights reserved

Stemness Features in Liver Cancer

Heterogeneity is a cardinal hallmark of cancer, including primary liver cancer (PLC), and occurs at different layers including putative cell-of-origin. Current evidence suggests that within cellular subpopulations in PLC there are stem-like cells, the cancer stem cells (CSCs). The CSC concept has been recently proposed as an explanation of such intra-tumor heterogeneity. According to this model, CSCs are responsible for tumor initiation, recurrence, metastasis as well as drug-resistance. However, although the CSC hypothesis is intriguing and supported by a large number of experimental studies, there are still open questions regarding the origin of putative CSCs. Since chemo-resistance and recurrence represent major issues in PLC treatment, the development of new therapeutic strategies is needed, for which a good understanding of tumor behavior and in particular of CSCs biology is an imperative prerequisite. In this review we summarize the regulatory pathways that support CSC features in PLC. Moreover, we highlight the key features of hepatic CSC, in terms of enhanced drug-resistance, increased metastatic potential and metabolic rearrangement. Knowledge of the molecular mechanisms underlying CSC biology may provide novel options for PLC combination therapies

The Northern wraps of the Sagittarius Stream as traced by Red Clump stars: distances, intrinsic widths and stellar densities

We trace the tidal Stream of the Sagittarius dwarf spheroidal galaxy (Sgr dSph) using Red Clump stars from the catalog of the Sloan Digital Sky Survey - Data Release 6, in the range 150{\deg} < RA < 220{\deg}, corresponding to the range of orbital azimuth 220{\deg} < Lambda < 290{\deg}. Substructures along the line of sight are identified as significant peaks in the differential star count profiles (SCP) of candidate Red Clump stars. A proper modeling of the SCPs allows us to obtain: (a) <10% accurate, purely differential distances with respect to the main body of Sgr, (b) estimates of the FWHM along the line of sight, and (c) estimates of the local density, for each detected substructure. In the range 255{\deg} < Lambda < 290{\deg} we cleanly and continuously trace various coherent structures that can be ascribed to the Stream, in particular: the well known northern portion of the leading arm, running from d~43 kpc at Lambda ~ 290{\deg} to d ~ 30 kpc at Lambda ~ 255{\deg}, and a more nearby coherent series of detections lying at constant distance d ~ 25 kpc, that can be identified with a wrap of the trailing arm. The latter structure, predicted by several models of the disruption of Sgr dSph, was never traced before; comparison with existing models indicates that the difference in distance between these portions of the leading and trailing arms may provide a powerful tool to discriminate between theoretical models assuming different shapes of the Galactic potential. A further, more distant wrap in the same portion of the sky is detected only along a couple of lines of sight.[abridged]Comment: 31 pages, 28 figures, accepted for publication in the Astrophysical Journal, a version with figures at full resolution can be downloaded at the following URL: http://www.bo.astro.it/SGR

HII regions within a compact high velocity cloud. A nearly star-less dwarf galaxy?

Within the SECCO survey we identified a candidate stellar counterpart to the Ultra Compact High Velocity Cloud (UCHVC) HVC274.68+74.70-123, that was suggested by Adams et al. (2013) as a possible mini-halo within the Local Group of galaxies. The spectroscopic follow-up of the brightest sources within the candidate reveals the presence of two HII regions whose radial velocity is compatible with physical association with the UVHVC. The available data does not allow us to give a definite answer on the nature of the newly identified system. A few alternative hypotheses are discussed. However, the most likely possibility is that we have found a new faint dwarf galaxy residing in the Virgo cluster of galaxies, which we name SECCO-1. Independently of its actual distance, SECCO-1 displays a ratio of neutral hydrogen mass to V luminosity of M_{HI}/L_V>= 20, by far the largest among local dwarfs. Hence, it appears as a nearly star-less galaxy and it may be an example of the missing links between normal dwarfs and the dark mini halos that are predicted to exist in large numbers according to the currently accepted cosmological model.Comment: Accepted for publication in ApJ Letters. Pdflatex, emulateapj.cls. 6 pages, 3 figures, 2 table