Steep Slopes and Preferred Breaks in GRB Spectra: the Role of Photospheres and Comptonization

The role of a photospheric component and of pair breakdown is examined in the internal shock model of gamma-ray bursts. We discuss some of the mechanisms by which they would produce anomalously steep low energy slopes, X-ray excesses and preferred energy breaks. Sub-relativistic comptonization should dominate in high comoving luminosity bursts with high baryon load, while synchrotron radiation dominates the power law component in bursts which have lower comoving luminosity or have moderate to low baryon loads. A photosphere leading to steep low energy spectral slopes should be prominent in the lowest baryon loadComment: ApJ'00, in press; minor revs. 10/5/99; (uses aaspp4.sty), 15 pages, 3 figure

Indicator systems - resource use in organic systems

A balanced use of resources within organic farming systems is required to maintain sustainable systems. Hence, it is essential to have tools that can assess the use of resources within the farming system and their impact on the environment. The range of tools that have been developed include those assessing local farm-scale issues together with those that assess impacts at the global scale. At the global scale assessments are usually made on the basis of a unit of product whereas at the local scale assessments can also be made on an area basis. In addition, the tools also assess a variety of issues, e.g. biodiversity, pollution potential, energy and water use. The level of detail required for the different assessment tools differs substantially; nevertheless it is essential that the indicator systems developed are based on sound knowledge, are acceptable to the farmers and can guide their future actions

Specific Enhancement of Transplantation Immunity with Heat-killed Mycobacterium Butyricum and Immunizing Extracts from Adenovirus 12-Induced Tumour Cells

Transplant immunity to adenovirus 12-induced tumour cells was demonstrated in CBA mice which had been previously immunized with extracts of homologous tumour cells. Immunization of mice with tumour cell extract together with heat-killed Mycobacterium butyricum gave better transplant immunity to tumour cell challenge than tumour extracts alone. Mice immunized with Mycobacterium butyricum alone prior to challenge with tumour cells, did not show any significant difference in the incidence of tumours from control mice

Crystallographic studies of the Escherichia coli quinol-fumarate reductase with inhibitors bound to the quinol-binding site

The quinol-fumarate reductase (QFR) respiratory complex of Escherichia coli is a four-subunit integral-membrane complex that catalyzes the final step of anaerobic respiration when fumarate is the terminal electron acceptor. The membrane-soluble redox-active molecule menaquinol (MQH(2)) transfers electrons to QFR by binding directly to the membrane-spanning region. The crystal structure of QFR contains two quinone species, presumably MQH(2), bound to the transmembrane-spanning region. The binding sites for the two quinone molecules are termed Q(P) and Q(D), indicating their positions proximal Q(P)) or distal (Q(D)) to the site of fumarate reduction in the hydrophilic flavoprotein and iron-sulfur protein subunits. It has not been established whether both of these sites are mechanistically significant. Co-crystallization studies of the E. coli QFR with the known quinol-binding site inhibitors 2-heptyl-4-hydroxyquinoline-N-oxide and 2-[1-(p-chlorophenyl)ethyl] 4,6-dinitrophenol establish that both inhibitors block the binding of MQH(2) at the Q(P) site. In the structures with the inhibitor bound at Q(P), no density is observed at Q(D), which suggests that the occupancy of this site can vary and argues against a structurally obligatory role for quinol binding to Q(D). A comparison of the Q(P) site of the E. coli enzyme with quinone-binding sites in other respiratory enzymes shows that an acidic residue is structurally conserved. This acidic residue, Glu-C29, in the E. coli enzyme may act as a proton shuttle from the quinol during enzyme turnover

AdS boundary conditions and the Topologically Massive Gravity/CFT correspondence

The AdS/CFT correspondence provides a new perspective on recurrent questions in General Relativity such as the allowed boundary conditions at infinity and the definition of gravitational conserved charges. Here we review the main insights obtained in this direction over the last decade and apply the new techniques to Topologically Massive Gravity. We show that this theory is dual to a non-unitary CFT for any value of its parameter mu and becomes a Logarithmic CFT at mu = 1.Comment: 10 pages, proceedings for XXV Max Born Symposium, talks given at Johns Hopkins workshop and Holographic Cosmology workshop at Perimeter Institute; v2: added reference