Effect of magnetic fluctuations on the normal state properties of Sr_2RuO_4

We investigate the normal state transport properties of Sr$_2$RuO$_4$ and we show that a consistent explanation of the experimental results can be obtained assuming that the system is near a quantum phase transition. Within the framework of a self-consistent spin fluctuation theory, we calculate the temperature variation of some relevant physical quantities and we discuss a possible microscopic origin of the quantum phase transition.Comment: 5 pages, 4 figures, to appear on Europhysics Letter

New features of the phase transition to superconducting state in thin films

The Halperin-Lubensky-Ma (HLM) effect of a fluctuation-induced change of the order of phase transition in thin films of type I superconductors with relatively small Ginzburg-Landau number $\kappa$ is considered. Numerical data for the free energy, the order parameter jump, the latent heat, and the specific heat of W, Al and In are presented to reveal the influence of film thickness and material parameters on the properties of the phase transition. We demonstrate for the first time that in contrast to the usual notion the HLM effect occurs in the most distinct way in superconducting films with high critical magnetic field $H_{c0}$ rather than in materials with small $\kappa$. The possibility for an experimental observation of the fluctuation change of the order of superconducting phase transition in superconducting films is discussed.Comment: 11 pages, MikTexTeX, 3 fig, 2 Tables, corrected some typos, Submitted J.Phys:Cond Ma

Intracellular expression of Tat alters mitochondrial functions in T cells: a potential mechanism to understand mitochondrial damage during HIV-1 replication

HIV-1 replication results in mitochondrial damage that is enhanced during antiretroviral therapy (ART). The onset of HIV-1 replication is regulated by viral protein Tat, a 101-residue protein codified by two exons that elongates viral transcripts. Although the first exon of Tat (aa 1–72) forms itself an active protein, the presence of the second exon (aa 73–101) results in a more competent transcriptional protein with additional functions. Results: Mitochondrial overall functions were analyzed in Jurkat cells stably expressing full-length Tat (Tat101) or one-exon Tat (Tat72). Representative results were confirmed in PBLs transiently expressing Tat101 and in HIV-infected Jurkat cells. The intracellular expression of Tat101 induced the deregulation of metabolism and cytoskeletal proteins which remodeled the function and distribution of mitochondria. Tat101 reduced the transcription of the mtDNA, resulting in low ATP production. The total amount of mitochondria increased likely to counteract their functional impairment. These effects were enhanced when Tat second exon was expressed. Conclusions: Intracellular Tat altered mtDNA transcription, mitochondrial content and distribution in CD4+ T cells. The importance of Tat second exon in non-transcriptional functions was confirmed. Tat101 may be responsible for mitochondrial dysfunctions found in HIV-1 infected patients.We greatly appreciate the secretarial assistance of Mrs Olga Palao. This work was supported by FIPSE (360924/10), Spanish Ministry of Economy and Competitiveness (SAF2010-18388), Spanish Ministry of Health (EC11- 285), AIDS Network ISCIII-RETIC (RD12/0017/0015), Instituto de Salud Carlos III, Spanish Ministry of Economy and Competitiveness (FIS PI12/00506). The work of Sara Rodríguez-Mora is supported by a fellowship of Sara Borrell from Spanish Ministry of Economy and Competitiveness (2013). The work of María Rosa López-Huertas is supported by a fellowship of the European Union Programme Health 2009 (CHAARM).S

Soft mode and spin-glass like transition in insulating glass

The spectrum and damping of collective excitations of a system of electric dipole centers with internal degrees of freedom in glass are calculated. It is shown that one of the collective modes becomes soft, signaling a spin-glass like phase transition in insulating glass. The contribution to the specific heat is determined. The possibility of phase transition from paraelectric to electric pseudospin glass phase in dielectric glass is considered. </jats:p