Infant-feeding patterns and the effects of early introduction to formula and solid foods on childhood overweight or obesity among 10-years-olds in a low socioeconomic area of Lebanon : an exploratory analysis

In Lebanon, there has been an alarming increase in childhood overweight and obesity. In addition, most mothers do not meet the WHO recommendation that infants should be introduced to formula or solids only during the second half of their first year. Because the study population, Burj Hammoud, which is a low socioeconomic district, is small, we performed an exploratory analysis of infant feeding patterns and the effects of introducing formula and solids within six months, respectively, on childhood overweight/obesity among 10-year-old children. A total of 101 mothers were recruited from seven intercommunity dispensaries located across the district. Descriptive, univariate and multivariate logistic regression analyses were performed. There were 86.1% infants initiating breastfeeding, 18% exclusively breastfeeding at 6 months of age, 67.1% and 52.6% starting formula and solids by 6 months, respectively, and 53.5% becoming overweight/obese by the age of 10 years. Working mothers were significantly less likely to introduce formula but not solids within the first six months of infancy. Based on two case-control studies, after controlling for maternal employment, there were 2.278- and 1.511-fold significantly higher odds of introducing solids and formula before the age of 6 months compared with after the age of 6 months, respectively, for the overweight/obese individuals among 10-year-olds. Future research should focus on conducting a larger study by incorporating other low socioeconomic regions to confirm these relationships

Integrated-boost IMRT or 3-D-CRT using FET-PET based auto-contoured target volume delineation for glioblastoma multiforme - a dosimetric comparison

<p>Abstract</p> <p>Background</p> <p>Biological brain tumor imaging using O-(2-[¹⁸F]fluoroethyl)-L-tyrosine (FET)-PET combined with inverse treatment planning for locally restricted dose escalation in patients with glioblastoma multiforme seems to be a promising approach.</p> <p>The aim of this study was to compare inverse with forward treatment planning for an integrated boost dose application in patients suffering from a glioblastoma multiforme, while biological target volumes are based on FET-PET and MRI data sets.</p> <p>Methods</p> <p>In 16 glioblastoma patients an intensity-modulated radiotherapy technique comprising an integrated boost (IB-IMRT) and a 3-dimensional conventional radiotherapy (3D-CRT) technique were generated for dosimetric comparison. FET-PET, MRI and treatment planning CT (P-CT) were co-registrated. The integrated boost volume (PTV1) was auto-contoured using a cut-off tumor-to-brain ratio (TBR) of ≥ 1.6 from FET-PET. PTV2 delineation was MRI-based. The total dose was prescribed to 72 and 60 Gy for PTV1 and PTV2, using daily fractions of 2.4 and 2 Gy.</p> <p>Results</p> <p>After auto-contouring of PTV1 a marked target shape complexity had an impact on the dosimetric outcome. Patients with 3-4 PTV1 subvolumes vs. a single volume revealed a significant decrease in mean dose (67.7 vs. 70.6 Gy). From convex to complex shaped PTV1 mean doses decreased from 71.3 Gy to 67.7 Gy. The homogeneity and conformity for PTV1 and PTV2 was significantly improved with IB-IMRT. With the use of IB-IMRT the minimum dose within PTV1 (61.1 vs. 57.4 Gy) and PTV2 (51.4 vs. 40.9 Gy) increased significantly, and the mean EUD for PTV2 was improved (59.9 vs. 55.3 Gy, p < 0.01). The EUD for PTV1 was only slightly improved (68.3 vs. 67.3 Gy). The EUD for the brain was equal with both planning techniques.</p> <p>Conclusion</p> <p>In the presented planning study the integrated boost concept based on inversely planned IB-IMRT is feasible. The FET-PET-based automatically contoured PTV1 can lead to very complex geometric configurations, limiting the achievable mean dose in the boost volume. With IB-IMRT a better homogeneity and conformity, compared to 3D-CRT, could be achieved.</p

Caffeine improves work durability and physical performance in anaerobic exercises among active adults in Tripoli Lebanon

Background: People worldwide have a high intake of caffeine. Active adults are among the group of people who have always been interested in caffeine as an ergogenic aid. This study aims at examining the association between caffeine consumption and perceived performance (aerobic and anaerobic exercises) among active people attending different gyms in Tripoli, Lebanon. Methods: A cross-sectional study was conducted on 206 participants attending seven gyms in Tripoli. Participants were recruited using simple random sampling for a face-to-face individual interview. Data were collected using a semi-structured questionnaire. Data have been coded, entered, and analyzed using SPSS software. Results: The prevalence rate of active people practicing both aerobic and anaerobic exercises is 63.6%. More than half of our sample (54.8%) has been working out for a duration of more than 6 months and 84.6% of respondents spend at least 30 min during their workouts. Caffeine consumption was popular in our sample with 92.2% indicating that they use caffeinated products. The findings of this study showed an association between anaerobic exercise and caffeine, perceived as physical performance enhancer and work durability enhancer. Yet no association was found between aerobic exercise and caffeine consumption. Conclusions: Perhaps, future research could focus on the safe doses of caffeine that could be given for anaerobic exercises to have an ergogenic effect. This could help us to build scientific guidelines for caffeine’s association with sports performance

Association of non-nutritive sweeteners intake with body weight, daily food consumption and appetite in an adult population

Summary: Background: Non-nutritive sweetener (NNS) is a substitute to sugar or nutritive sweetener, those that imitate the flavor of sugar but with less calories. This study evaluated the impact of NNS consumption on daily food intake, appetite and weight control among adults in Mount Lebanon. Methods: An online survey was conducted among 553 adults aged 18–55 years in a low socioeconomic district Mount Lebanon. A cross-sectional study design, and snowballing sampling with sample size 553 were used in the study. Chi-squared test and t test for tetrachoric correlation were used for bivariate analysis, while partial proportional odds logistic, polychotomous logistic and multiple linear models were used for multivariate analysis. Results: Compared to those not consuming NNS, the odds of grains, bread, artificially sweetened non-alcoholic beverages, snacks consumptions were significantly lower for those consuming NNS ‘once a day’ and ‘2–3 times a day’; ‘2–3 times a day’ and ‘4–5 times a day’; '4–5 times a day’; ‘3–4 times a day’ and ‘5 or more times a day’. NNS consumers did not significantly have lower odds of high frequency meals and appetite respectively than non-consumers. There was no evidence of difference in BMI between NNS consumers versus non-consumers. Conclusion: NNS is associated with grains, bread, artificially sweetened non-alcoholic beverages and snacks but not with meals when it is taken in combination with the item. This study provides the basis for future research on NNS consumption in Lebanon

Elevation-layered dendroclimatic signal in eastern Mediterranean tree rings

Networks of tree-ring data are commonly applied in statistical reconstruction of spatial fields of climate variables. The importance of elevation to the climatic interpretation of tree-ring networks is addressed using 281 station precipitation records, and a network of 79 tree-ring chronologies from different species and a range of elevations in the eastern Mediterranean. Cluster analysis of chronologies identifies 6 tree-ring groups, delineated principally by site elevation. Correlation analysis suggests several of the clusters are linked to homogenous elevational moisture regimes. Results imply that climate stations close to the elevations of the tree-ring sites are essential for assessing the seasonal climatic signal in tree-ring chronologies from this region. A broader implication is that the elevations of stations contributing to gridded climate networks should be considered in the design and interpretation of field reconstructions of climate from tree rings. Finally, results suggest elevation-stratified tree-ring networks as a strategy for seasonal climate reconstruction