Machine & Process Parameters for additive manufacturing of eutectic Al-Ni(-Cu)

Attached are the machine & process parameters for the additive manufacturing of eutectic Al-Ni-alloys as described in the paper "Additive Manufacturing of high strength eutectic Aluminium Nickel alloys – Processing and Mechanical Properties". Additionally the applied standard and sample dimensions for tensile testing are given

El Mercado Único. La Europa sin Fronteras Interiores: la información en el etiquetado en Sanidad y Consumo. Universidad Politécnica de Madrid

Duración del vídeo: 1h 22min 05sCiclo de conferencias sobre el Mercado Único dentro de la Acción Institucional'93 celebrado en la Universidad Politécnica de Madrid y presidido por el Secretario de Estado para las CC.EE, D. Carlos Westendorp junto con el Rector de la Universidad Politécnica de Madrid D. Rafael Portaencasa

Clinical and biometrical 12-month follow-up in patients after reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix

Many new strategies for the reconstruction of peripheral nerve injuries have been explored for their effectiveness in supporting nerve regeneration. However only a few of these materials were actually clinically evaluated and approved for human use. This open, mono-center, non-randomized clinical study summarizes the 12-month follow-up of patients receiving reconstruction of the sural nerve biopsy defect by the collagen-based nerve guide Neuromaix. Neuromaix was implanted as a micro-structured, two-component scaffold bridging 20–40 mm nerve defects after sural nerve biopsy in twenty patients (eighteen evaluated, two lost in follow-up). Safety of the material was evaluated by clinical examination of wound healing. Performance was assessed by sensory testing of modalities, pain assessment, and palpation for the Hoffmann–Tinel’s sign as well as demarcating the asensitive area at each follow-up visit. Every patient demonstrated uneventful wound healing during the complete 12-month time course of the study. Two patients reported complete return of sensation, whereas eleven out of eighteen patients reported a positive Hoffmann–Tinel’s sign at the lower leg with simultaneous reduction of the asensitive area by 12 months. Our data show that Neuromaix can be implanted safely in humans to bridge sural nerve gaps. No procedure-related, adverse events, or severe adverse events were reported. These first clinical data on Neuromaix provide promising perspectives for the bridging of larger nerve gaps in combined nerves, which should be investigated more through extensive, multi-center clinical trials in the near future

Ultrafine Fe-Fe2Ti eutectics by directed energy deposition: Insights into microstructure formation based on experimental techniques and phase field modelling

We investigated the Fe-Fe2Ti eutectic microstructure obtained by Directed Energy Deposition (DED) with a hypereutectic composition of Fe-17.6 at.% Ti. Ultrafine lamellar spacings as low as 200 nm were achieved, features which otherwise can only be obtained in thin specimens, e.g. by suction casting. However, at interlayer boundaries (ILBs) a globular morphology of the primary Fe2Ti phase is observed with halos of the Fe phase. For the given DED conditions the crystalline structure is thus discontinuous across the ILBs. Both 2D and 3D analysis methods were used to quantify the microstructure, including high resolution synchrotron holographic X-ray computed tomography (HXCT). The generic behaviour of eutectic systems under conditions that qualitatively correspond to those of laser additive manufacturing was explored by phase-field modelling for selected nucleation scenarios and alloy compositions spanning from eutectic to hyper-eutectic. While providing valuable insights into microstructure formation, the simulations point out the need to further deepen our understanding about melting under additive manufacturing conditions in order to implement suitable nucleation and / or free growth models. The simulations also show that globular ILBs can be prevented when using exactly eutectic alloy compositions