Implementation of Application Packaging Technology in Healthcare Industry

Application packaging bundles applications for operating systems into a single file called a distribution unit (.msi), which makes the administrator work easier to deploy and install them on user\u27s computers. This project was about repackaging Adobe Reader and after successful repackaging of the application, the customization of Adobe was done with the help of Adobe Customization Wizard. By applying Software Development Life Cycle (SDLC) methodology based on the requirement the packagers were able to create detailed analysis on Adobe Reader to support each step involved in managing a desktop application from deployment through retirement. The main objective of this project was to analyze the data to make the required and necessary customizations to the Adobe Reader to save time and effort. Application packaging can be important component for efficiently managing the increased volume of software on desktop and notebook systems. By streamlining software installation, uninstallation, repair, and patching, application packaging can help reduce costs associated with each phase of the application deployment and support life cycle

Bioactive Peptides from Milk

Milk is a major source of dietary energy, protein and fat. Due to their specific biological properties leading to health benefits, bioactive peptides (BAPs) derived from milk proteins have been a subject of intensive research during past two decades. These peptide sequences, encrypted within proteins, are liberated in vivo during gastrointestinal digestion or in vitro by fermentation with proteolytic starter cultures or using proteases. BAP generally comprises 2–20 amino acid (AA) residues. Isolation and characterization of BAP of different bioactivities from milk protein hydrolysates of cow, buffalo, camel, goat, mare, sheep, donkey and yak milks have been reported. Bioactivities of BAP, which depend on constituent AAs and the sequence, include mineral binding, opioid, angiotensin-converting enzyme (ACE) inhibition, immunomodulatory, cytotoxicity, antibacterial and antithrombotic. This chapter focuses on the methodologies adopted to produce BAPs and their prospective role in health enhancing nutraceuticals/pharmaceuticals

Cost variation analysis of various brands of anti-retroviral agents currently available in Indian market: an economic perspective study

Background: The aim was to analyze the percentage cost variations among different brands of the commonly prescribed anti-retroviral agents in the treatment of human immunodeficiency virus.Methods: The cost of different brands of commonly used Anti-Retroviral agents was sorted out by referring latest Indian drug index online, drug today, current index of medical specialties, Indian drug review.Results: The percentage variation in the cost was above 100% with most of the commonly used anti-retroviral agents. Overall sequinafir 500 mg shows maximum cost variation of 1490.3%, while nelfinavir (625 mg) shows minimum cost variation of 6.1% in single drug therapy. Lamivudine 300 mg and tenofovir 300 mg combination shows maximum cost variation of 14055% whereas, lamivudine 150 mg, zidovudine 300 mg and efavirenz 600 mg shows minimum cost variation of 10% in combination drug therapy.Conclusions: HIV is the most common infectious, life-threatening disease and drugs are to be prescribed for life-long period. If a costly brand is prescribed, the patients cannot afford to pay more money for their treatment. This also leads to poor patient compliance, dissatisfaction and failure of the treatment. Ideally, therefore, the drugs should be prescribed in such a way, to save the patient's economic burden and enhance the compliance of the treatment

Combining depth and intensity images to produce enhanced object detection for use in a robotic colony

Robotic colonies that can communicate with each other and interact with their ambient environments can be utilized for a wide range of research and industrial applications. However amongst the problems that these colonies face is that of the isolating objects within an environment. Robotic colonies that can isolate objects within the environment can not only map that environment in de-tail, but interact with that ambient space. Many object recognition techniques ex-ist, however these are often complex and computationally expensive, leading to overly complex implementations. In this paper a simple model is proposed to isolate objects, these can then be recognize and tagged. The model will be using 2D and 3D perspectives of the perceptual data to produce a probability map of the outline of an object, therefore addressing the defects that exist with 2D and 3D image techniques. Some of the defects that will be addressed are; low level illumination and objects at similar depths. These issues may not be completely solved, however, the model provided will provide results confident enough for use in a robotic colony

A comparative study to assess the effectiveness of structured teaching programme on knowledge, attitude and practice regarding menarche and menstrual management among school girls in selected urban and rural schools at Coimbatore

OBJECTIVES: The main objective of my study was to assess the average age at menarche, assess the effectiveness of structured teaching programme, compare and associate the knowledge, attitude and practice between rural and urban school girls. DESIGN: The quasi experimental pre test and post test design. SAMPLING TECHNIQUE: Non probability purposive sampling technique. CONCEPTUAL FRAMEWORK: modified weidenbach’s theory of helping art of clinical nursing. TOOL FOR DATA COLLECTION: Structured self administered questionnaire to assess the knowledge, likert scale to assess the attitude, checklist to assess the practice. INTERVENTION: LCD teaching was given to both schools after pre test assessment. RESULTS: In rural school the average age at menarche was 12.11 and in the urban school 12.12 and it shows girls attained menarche at minimum age of 10 yrs. The paired t test value of pre test and post test of urban and rural school shows highly significant at p < 0.01 regarding knowledge, attitude and practice. The comparison between rural and urban school shows that it was significant in pre test of knowledge, attitude and practice but post test shows that there was no significant difference between post test attitude and practice. The association of rural school shows that there was significant association between types of family, BMI, family income at p < 0.05. In urban school there was no significant association between family incomes and there was significant association between types of family, BMI at p < 0.05. CONCLUSION: The study concluded after teaching programme there were a marked difference between the knowledge, attitude and practice among rural and urban school girls regarding menstrual management. The study highlights that as professionals we have to conduct this kind of school health programme to ensure the quality of health

Effectiveness of Nanoparticle Based Acidulated Phosphate Fluoride (APF) Gel on Surface Enamel Fluoride Uptake: An Interventional study

AIM OF THE STUDY: To assess the effectiveness of nanoparticle based acidulated phosphate fluoride (APF) gel on surface enamel fluoride uptake. OBJECTIVES: 1. To assess the surface enamel fluoride uptake in the tooth pre-operatively using acid etch biopsy method given by Brunn et al 1975. 2. To assess the change in the surface enamel fluoride uptake after the application of nanoparticle based APF gel after a period of 24hrs and 30 days using acid etch biopsy method given by Brunn et al 1975. 3. To assess the change in the surface enamel fluoride uptake after the application of conventional APF gel after a period of 24hrs and 30 days using acid etch biopsy method given by Brunn et al 1975. 4. To compare the difference in surface enamel fluoride uptake between nanoparticles based APF and conventional APF. 5. To determine the depth of penetration of nanoparticles based APF and conventional APF from the extracted teeth surface and compare the same with the help of scanning electron microscope (SEM). METHODOLOGY: The intervention split mouth study was conducted over a period of six months from May to November 2018, on patients undergoing orthodontic treatment and indicated for bilateral extraction of premolars on at least one of the arch. Each participant received one application of 4 minutes duration of both the intervention: Right half of the mouth received nanoparticle based APF gel, and left half of the mouth received conventional APF gel (16 Oz Pascal Corp.; Strawberry Flavour). A total of 30 participants were included in the study. Oral examination and prophylaxis prior to the commencement of the study as all the subjects were patients undergoing orthodontic treatment. Acid etch enamel biopsy was taken for all the study subjects preoperatively and post-operatively, bilaterally on the buccal and palatal/lingual surface of maxillary or mandibular premolars indicated for extraction, using 1 µl of 0.5M perchloric acid according to the method suggested by Brunn et. Al., in 1975. The surface enamel fluoride uptake and biopsy depth were estimated at 3 intervals of time namely baseline, 24hrs and 30 days. After the premolars were extracted, scanning electron microscope (SEM) analysis was done to determine the surface characteristics of enamel in both the nanoparticles based APF and conventional APF gel group. The data was collected and analyzed using SPSS software and results were generated. RESULTS: The mean levels of surface enamel fluoride at the baseline were found to be 1487.69±826.8 ppm, 1509.39±844.83 ppm in the nanoparticle based gel group and conventional APF group respectively. The biopsy depths were found to be 71.15±3.18 µ and 70.92±2.95 µ respectively in both groups at the baseline. Overall comparison of the two groups using Generalized Estimating Equations (GEE) showed, both fluoride uptake and depth of biopsy remained significant even after controlling for the covariates (time, group) individually and simultaneously with p value < 0.001. Further analysis between the groups at individual time points showed that fluoride uptake was significantly increased in the nanoparticle based APF gel group at 24 hour evaluation with a mean value of 5495.25±2171.12 ppm and biopsy depth significantly decreased in the nanoparticle based APF group, with a mean value of 69.33 ± 2.11 µ at the 30 day evaluation. CONCLUSION: The overall study results showed a marked increase in the surface enamel fluoride uptake and decrease in the mean depth of biopsy on using nanoparticle APF gel. Further clinical evaluation should be done to alter the duration of application time and frequency of application with respect to conventional APF gel in order to establish the efficacy of this new formulation

Modified Context Aware Middleware Architecture for Precision Agriculture

The opportunities for researchers are enhanced with the progression in the technology of communication and computing. The ease in life of many people like farmers, educators, administers, managers, etc., is increased with more inventions of the researchers using this new technology. The progressive technology for data management is providing more amount of information. However, is the user able to access the needed information when required? This question rises to the more questions like, how to identify whether the information is as per the requirement? Whether a user is authorized or not? The answer for all the questions is to make the support aware of the context. Therefore, the present technology needs to be modified to make the system aware about the context. The process of demonstrating the services based on the context using Wireless Sensor Networks (WSN) with the help of illustration on mango crop is emphasized in this paper. There are many serious problems like unsuitable fertilizer use, wrong selection of crops in wrong seasons, water waste, poor publicizing in the case of farming. These problems are addressed using the ubiquitous context aware middleware architecture for precision agriculture in mango crop

Cyclohepta[de]naphthalenes and the Rearranged Abietane Framework of Microstegiol via Nicholas Reaction Chemistry

Nicholas reactions on 2,7-dioxygenated naphthalenes give C-1 monosubstitution and C-1/C-8 disubstitution in most cases. From gamma-carbonyl cation monocondensation product 3b or alkyne-unsubstituted dicondensation product 4a, cyclohepta[de]naphthalenes bearing no substituents, gem-dimethyl substituents, and a ketone function, and the rearranged abietane framework of microstegiol may be prepared

Nutritional requirement at high-altitude with special emphasises to behaviour of gastro-intestinal tract and hormonal changes

When people are exposed to the extreme environmental conditions, such as high altitude (HA) where there is decrease in temperature and partial pressure of oxygen induces fatigue, insomnia, loss of appetite and increased cardiac output. Hence there is need to improve the appetite through the diet and digestion clout of the individual. In the present review paper we have discussed the efficiency of digestion is compromised at HA. Also about, Hypoxia, resulting by decreased partial pressure of oxygen can be classified into acute hypoxia and chronic hypoxia based on the exposure time. There is increased formation of reactive oxygen species (ROS) due to less oxygen available in the air at HA which leads to oxidative stress. Lipid peroxidation caused by oxidative stress. Hypoxia is mediated through hypoxia inducible factors which maintain oxygen haemostasis in the body. At HA diet rich in carbohydrates have been found to be beneficial as it increases glucose metabolism. Requirement of nutrients such as vitamin A, vitamin E and vitamin C as well as micronutrients such as zinc, iron, selenium, copper and manganese will be required at HA. Hypoxia effect on the intestine leads to malabsorption and the lipid storage is stimulated and lipid catabolism is inhibited through β-oxidation