2,963 research outputs found
Search for Intermediate Mass Magnetic Monopoles and Nuclearites with the SLIM experiment
SLIM is a large area experiment (440 m2) installed at the Chacaltaya cosmic
ray laboratory since 2001, and about 100 m2 at Koksil, Himalaya, since 2003. It
is devoted to the search for intermediate mass magnetic monopoles (107-1013
GeV/c2) and nuclearites in the cosmic radiation using stacks of CR39 and
Makrofol nuclear track detectors. In four years of operation it will reach a
sensitivity to a flux of about 10-15 cm-2 s-1 sr-1. We present the results of
the calibration of CR39 and Makrofol and the analysis of a first sample of the
exposed detector.Comment: Presented at the 22nd ICNTS, Barcelona 200
Search for massive rare particles with the SLIM experiment
The search for magnetic monopoles in the cosmic radiation remains one of the
main aims of non-accelerator particle astrophysics. Experiments at high
altitude allow lower mass thresholds with respect to detectors at sea level or
underground. The SLIM experiment is a large array of nuclear track detectors at
the Chacaltaya High Altitude Laboratory (5290 m a.s.l.). The results from the
analysis of 171 m exposed for more than 3.5 y are here reported. The
completion of the analysis of the whole detector will allow to set the lowest
flux upper limit for Magnetic Monopoles in the mass range 10 - 10
GeV. The experiment is also sensitive to SQM nuggets and Q-balls, which are
possible Dark Matter candidates.Comment: Presented at the 29-th ICRC, Pune, India (2005
Somatization among ethnic minorities and immigrants: Why does it matter to Consultation Liaison Psychiatry?
The article describes the reasons why psychiatrists working in the field of consultation-liaison should be trained and aware of the relevance of culture in their everyday work. Moreover, the article aims at advertising the special-interest group on cultural CLP, a network of clinicians and researchers within the European Association of Psychosomatic Medicine that share their interest and activities in this subject
Iron bioavailability in two commercial cultivars of wheat: a comparison between wholegrain and white flour and the effects of nicotianamine and 2'-deoxymugineic acid on iron uptake into Caco-2 cells
Iron bioavailability in unleavened white and wholegrain bread made from two commercial wheat varieties was assessed by measuring ferritin production in Caco-2 cells. The breads were subjected to simulated gastrointestinal digestion and the digests applied to the Caco-2 cells. Although Riband grain contained a lower iron concentration than Rialto, iron bioavailability was higher. No iron was taken up by the cells from white bread made from Rialto flour or from wholegrain bread from either variety, but Riband white bread produced a small ferritin response. The results probably relate to differences in phytate content of the breads, although iron in soluble monoferric phytate was demonstrated to be bioavailable in the cell model. Nicotianamine, an iron chelator in plants involved in iron transport, was a more potent enhancer of iron uptake into Caco-2 cells than ascorbic acid or 2'-deoxymugineic acid, another metal chelator present in plants
Opposing brain differences in 16p11.2 deletion and duplication carriers
Deletions and duplications of the recurrent âŒ600 kb chromosomal BP4âBP5 region of 16p11.2 are associated with a broad variety of neurodevelopmental outcomes including autism spectrum disorder. A clue to the pathogenesis of the copy number variant (CNV)'s effect on the brain is that the deletion is associated with a head size increase, whereas the duplication is associated with a decrease. Here we analyzed brain structure in a clinically ascertained group of human deletion (N = 25) and duplication (N = 17) carriers from the Simons Variation in Individuals Project compared with age-matched controls (N = 29 and 33, respectively). Multiple brain measures showed increased size in deletion carriers and reduced size in duplication carriers. The effects spanned global measures of intracranial volume, brain size, compartmental measures of gray matter and white matter, subcortical structures, and the cerebellum. Quantitatively, the largest effect was on the thalamus, but the collective results suggest a pervasive rather than a selective effect on the brain. Detailed analysis of cortical gray matter revealed that cortical surface area displays a strong dose-dependent effect of CNV (deletion > control > duplication), whereas average cortical thickness is less affected. These results suggest that the CNV may exert its opposing influences through mechanisms that influence early stages of embryonic brain development
C5 Palsy After Cervical Spine Surgery: A Multicenter Retrospective Review of 59 Cases.
STUDY DESIGN: A multicenter, retrospective review of C5 palsy after cervical spine surgery.
OBJECTIVE: Postoperative C5 palsy is a known complication of cervical decompressive spinal surgery. The goal of this study was to review the incidence, patient characteristics, and outcome of C5 palsy in patients undergoing cervical spine surgery.
METHODS: We conducted a multicenter, retrospective review of 13â946 patients across 21 centers who received cervical spine surgery (levels C2 to C7) between January 1, 2005, and December 31, 2011, inclusive. P values were calculated using 2-sample t test for continuous variables and Ï(2) tests or Fisher exact tests for categorical variables.
RESULTS: Of the 13â946 cases reviewed, 59 patients experienced a postoperative C5 palsy. The incidence rate across the 21 sites ranged from 0% to 2.5%. At most recent follow-up, 32 patients reported complete resolution of symptoms (54.2%), 15 had symptoms resolve with residual effects (25.4%), 10 patients did not recover (17.0%), and 2 were lost to follow-up (3.4%).
CONCLUSION: C5 palsy occurred in all surgical approaches and across a variety of diagnoses. The majority of patients had full recovery or recovery with residual effects. This study represents the largest series of North American patients reviewed to date
Hemispherical power asymmetry: parameter estimation from CMB WMAP5 data
We reexamine the evidence of the hemispherical power asymmetry, detected in
the CMB WMAP data using a new method. At first, we analyze the hemispherical
variance ratios and compare these with simulated distributions. Secondly,
working within a previously-proposed CMB bipolar modulation model, we constrain
model parameters: the amplitude and the orientation of the modulation field as
a function of various multipole bins. Finally, we select three ranges of
multipoles leading to the most anomalous signals, and we process corresponding
100 Gaussian, random field (GRF) simulations, treated as observational data, to
further test the statistical significance and robustness of the hemispherical
power asymmetry. For our analysis we use the Internally-Linearly-Coadded (ILC)
full sky map, and KQ75 cut-sky V channel, foregrounds reduced map of the WMAP
five year data (V5). We constrain the modulation parameters using a generic
maximum a posteriori method.
In particular, we find differences in hemispherical power distribution, which
when described in terms of a model with bipolar modulation field, exclude the
field amplitude value of the isotropic model A=0 at confidence level of ~99.5%
(~99.4%) in the multipole range l=[7,19] (l=[7,79]) in the V5 data, and at the
confidence level ~99.9% in the multipole range l=[7,39] in the ILC5 data, with
the best fit (modal PDF) values in these particular multipole ranges of A=0.21
(A=0.21) and A=0.15 respectively. However, we also point out that similar or
larger significances (in terms of rejecting the isotropic model), and large
best-fit modulation amplitudes are obtained in GRF simulations as well, which
reduces the overall significance of the CMB power asymmetry down to only about
94% (95%) in the V5 data, in the range l=[7,19] (l=[7,79]).Comment: 24 pages, 10 figures; few typos corrected; published in JCA
A Quintessentially Geometric Model
We consider string inspired cosmology on a solitary -brane moving in the
background of a ring of branes located on a circle of radius . The motion of
the -brane transverse to the plane of the ring gives rise to a radion field
which can be mapped to a massive non-BPS Born-Infeld type field with a cosh
potential. For certain bounds of the brane tension we find an inflationary
phase is possible, with the string scale relatively close to the Planck scale.
The relevant perturbations and spectral indices are all well within the
expected observational bounds. The evolution of the universe eventually comes
to be dominated by dark energy, which we show is a late time attractor of the
model. However we also find that the equation of state is time dependent, and
will lead to late time Quintessence.Comment: 11 pages, 3 figures. References and comments adde
Electronic Structure Calculation by First Principles for Strongly Correlated Electron Systems
Recent trends of ab initio studies and progress in methodologies for
electronic structure calculations of strongly correlated electron systems are
discussed. The interest for developing efficient methods is motivated by recent
discoveries and characterizations of strongly correlated electron materials and
by requirements for understanding mechanisms of intriguing phenomena beyond a
single-particle picture. A three-stage scheme is developed as renormalized
multi-scale solvers (RMS) utilizing the hierarchical electronic structure in
the energy space. It provides us with an ab initio downfolding of the global
band structure into low-energy effective models followed by low-energy solvers
for the models. The RMS method is illustrated with examples of several
materials. In particular, we overview cases such as dynamics of semiconductors,
transition metals and its compounds including iron-based superconductors and
perovskite oxides, as well as organic conductors of kappa-ET type.Comment: 44 pages including 38 figures, to appear in J. Phys. Soc. Jpn. as an
invited review pape
Choice in the context of informal care-giving
Extending choice and control for social care service users is a central feature of current English policies. However, these have comparatively little to say about choice in relation to the informal carers of relatives, friends or older people who are disabled or sick. To explore the realities of choice as experienced by carers, the present paper reviews research published in English since 1985 about three situations in which carers are likely to face choices: receiving social services; the entry of an older person to long-term care; and combining paid work and care. Thirteen electronic databases were searched, covering both the health and social care fields. Databases included: ASSIA; IBSS; Social Care Online; ISI Web of Knowledge; Medline; HMIC Sociological Abstracts; INGENTA; ZETOC; and the National Research Register. The search strategy combined terms that: (1) identified individuals with care-giving responsibilities; (2) identified people receiving help and support; and (3) described the process of interest (e.g. choice, decision-making and self-determination). The search identified comparatively few relevant studies, and so was supplemented by the findings from another recent review of empirical research on carers' choices about combining work and care. The research evidence suggests that carers' choices are shaped by two sets of factors: one relates to the nature of the care-giving relationship; and the second consists of wider organisational factors. A number of reasons may explain the invisibility of choice for carers in current policy proposals for increasing choice. In particular, it is suggested that underpinning conceptual models of the relationship between carers and formal service providers shape the extent to which carers can be offered choice and control on similar terms to service users. In particular, the exercise of choice by carers is likely to be highly problematic if it involves relinquishing some unpaid care-giving activities
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