Double burden of malnutrition as a risk factor for overweight and obesity

OBJECTIVE To assess the longitudinal effect of double burden of malnutrition (DBM) on the risk of developing child and adolescent overweight or obesity. METHODS Analysis of the Peruvian Young Lives Study, younger cohort: baseline (2002) and 4 follow-ups (2006–2007, 2009–2010, 2013–2014, and 2016–2017). Outcomes were the incidence of overweight and obesity as defined by the World Health Organization standards. The exposure comprised a variable with 4 categories: non-stunted child with a non-overweight mother (reference group), non-stunted child with an overweight mother, stunted child with a non-overweight mother, and stunted child with an overweight mother (i.e., DBM). Poisson regression models were built to assess the association of interest, and relative risks (RR) and 95%CI were reported. RESULTS Data from 2,034 children; 50.0% were girls and the mean age was 12.0 (3.6) months at baseline. Non-stunted children with an overweight mother had greater risk (RR = 1.64; 95%CI: 1.35–1.99) of developing overweight, compared with the risk for stunted children with a non-overweight mother (RR = 1.38; 95%CI: 1.10–1.72), and for those with DBM (RR = 1.28; 95%CI: 1.02–1.61). When compared with the reference group, obesity risk was greater among non-stunted children with an overweight mother (RR = 2.33; 95%CI: 1.68–3.22), greater among stunted children with a non-overweight mother (RR = 2.59; 95%CI: 1.75–3.84), and greater among those with DBM (RR = 2.14; 95%CI: 1.39–3.28). CONCLUSIONS DBM is a risk factor for childhood overweight and obesity in Peru. Dual-duty policies tackling both undernutrition in children and overweight in mothers are needed to reduce DBM and its future effects in Peru

Crecimiento de renuevos y expansión de copas en claros del dosel de bosques de Nothofagus pumilio (lenga) en Chubut, Patagonia, Argentina

In the province of Chubut in Patagonia, Argentina, Nothofagus pumilio forests (locally known as lenga), are managed through selective cuts, which imply the opening of canopy gaps. This management scheme is carried out without taking into consideration the sapling requirements changes through neither a cutting cycle nor the precipitation gradient in which these forests thrive. To analyze these changes, we inferred the facilitation-competition balance between the canopy and regeneration studying the effects of precipitation levels, gap size and gap age on saplings growth in height on 45 canopy gaps artificially created between 1960 and 1993. Results shown that during the first 20 years since the gap opening, the regeneration growth is determined by light availability in mesic sites and by water availability in dry sites. However, the difference due to the precipitation levels gradually decreases over time. Moreover, in the period between 20 and 35 years after gap opening, in both mesic and xeric sites, light is the limiting factor to growth. This means that in xeric sites, saplings shift from a water-dependent to a light-dependent growth. The average closing rate of gaps due to lateral growth of trees bordering the gap is high enough so that within the proposed gap size range, the gap healing can occur before regeneration reaches the upper stratum. Consequently, in mesic sites the gap opening can be done by a single operation that generates gaps with diameters of approximately twice the average height of the canopy (D/H). While in xeric environments, lenga seedling establishment and initial growth require the cover of small gaps, but advanced regeneration requires bigger gaps to reach the canopy. For this reason, gaps should be opened in two stages: the first gaps should be opened with a D/H between 0.8 and 1, and after a cutting cycle of 35 years, these openings should be enlarged to a D/H between 1.5 and 2. The close relationship is maintained between the new cohort and the upper strata require special considerations regarding the evolution of the balance between positive and negative interactions during development. Our work highlights the need to adjust management practices to these spatial and temporal variations so as to achieve an optimal growth along the entire production cycle.En la provincia del Chubut, Patagonia Argentina, los bosques de Nothofagus pumilio (lenga) son manejados mediante cortas de selección, que implican la apertura de claros en el dosel. Este esquema de manejo es implementado sin tener en cuenta los requerimientos de los renuevos a lo largo de todo el ciclo de cortas ni el gradiente de precipitaciones presente en su distribución. Para analizar estos aspectos estimamos el balance facilitación-competencia entre el dosel y la regeneración, considerando los efectos de los niveles de precipitación, el tamaño de los claros y la antigüedad de los mismos, en 45 claros creados artificialmente entre los años 1960 y 1993. Los resultados muestran que durante los primeros 20 años desde la apertura del claro, el crecimiento de la regeneración está determinado por la disponibilidad de luz en los sitios mésicos y por la disponibilidad de agua en los sitios xéricos. Sin embargo, la diferencias entre los distintos niveles de precipitación decrece gradualmente a lo largo del tiempo y entre los 20 a 35 años luego de la apertura de los claros, tanto en los sitios mésicos como xéricos el factor limitante es la luz. Esto implica que en los sitios xéricos el crecimiento de los renuevos pasa de ser dependiente del agua a dependiente de la luz. Por otro lado, la tasa de cierre de los claros debida al crecimiento lateral de la copa de los árboles límite es lo suficientemente grande como para que pueda ocurrir el cierre antes de que los renuevos alcancen el estrato superior. Por lo tanto, en los sitios mésicos la apertura de los claros puede realizarse en una única operación que genere claros con un diámetro de aproximadamente el doble de la altura dominante del bosque (D/H ≈ 2). Por el contrario, en los sitios xéricos, el establecimiento y crecimiento inicial de los renuevos requiere la apertura de claros pequeños (D/H entre 0,8 y 1) que luego deberán ser ampliados para maximizar el crecimiento avanzado (D/H entre 1,5 y 2). La estrecha relación entre la regeneración y el dosel del bosque requiere la consideración de los posibles cambios en el balance entre los apsectos positivos y negativos de la misma a lo largo de todo su desarrollo. Nuestro trabajo resalta la necesidad de ajustar las prácticas de manejo a estas variaciones espaciales y temporales para alcanzar un desarrollo óptimo a lo largo del todo el ciclo productivo

IDENTIFICATION OF FATTY ACIDS IN SACHA INCHI OIL (CURSIVE PLUKENETIA VOLUBILIS L.) FROM ECUADOR

Objective: The aim of this study was to identify fatty acids in a sacha inchi oil sample.Methods: Sacha inchi oil was obtained of sacha inchi seeds using the cold pressing method. Fatty acids analysis was carried out using the gas chromatography with a mass selective detector and using the database Library NIST14.L to identify the compounds.Results: Sacha inchi seeds have a high content of unsaturated fatty acids with 34.98% of ɷ6 α- Linoleic and 47.04% of ɷ3 α- Linolenic. Sacha inchi seeds only have 3.98% of palmitic acid.Conclusions: Sacha inchi seed is a good source of fatty acids ɷ3 and ɷ6, being ɷ3 and ɷ6 in a good proportion. Sacha inchi oil can be used to elaborate functional foods

Narrative Review on the Therapeutic Approach to Violence against Women during the COVID-19 Pandemic in Latin America

Violence against women during the pandemic has become a problem that has affected the world and to date has caused the death of many women. Although mental health has shown a growing interest in research, it is still very susceptible to being affected. This research described the scientific literature on the challenges in the psychotherapeutic approach in victims of violence against women during the COVID-19 pandemic in Latin America. A narrative review was carried out with a search of documents in the Scopus, Web of Science and PubMed databases, using descriptors for women, violence against women, COVID-19 and Latin America. As a result, 12 studies were included, which reported that the use of helplines, digital platforms of care and teletherapy were advantageous in several Latin American countries during the pandemic; difficulties were found in the accessibility of care for cases, collapse of telephone lines, technical problems of the system and the need for training for health professionals and service providers. It can be concluded that the coping strategies most used during the pandemic were the help services, through telephone and virtual care; there was difficulty in following up and monitoring the case in the medium and long terms, so further studies could focus on it. The main limitation of this work is methodological, since a number of studies could have been excluded from the searches for not including some of the terms in the search equation

Summer diet of cattle grazing in lenga forests (Nothofagus pumilio) and flood meadows of Chubut, Argentina

Se determinó la composición de la dieta de verano de bovinos pastoreando en sistemas formados por bosques de Nothofagus pumilio (lenga) y mallines, del noroeste del Chubut. Se estimó la disponibilidad forrajera de los mallines y del sotobosque mediante cortes de biomasa aérea, y se determinó la composición dietaria mediante análisis microhistológico de heces. La dieta está integrada principalmente por especies de gramíneas y graminoides, que disminuyeron su frecuencia al final del verano, mientras que los renovales de lenga y otras especies leñosas la aumentaron. El ganado selecciona gramíneas en ambos períodos, y al final del verano también los renovales de lenga. La ganadería constituye una importante y creciente forma de subsistencia para los pobladores rurales del noroeste del Chubut. Este trabajo aporta elementos para avanzar en la búsqueda de herramientas que permitan la sustentabilidad de los bosques de lenga.Summer diet composition of cattle grazing in systems formed by Nothofagus pumilio forests (lenga) and flood meadows, in Northwest of Chubut, was determined. Forage availability in flood meadows and understory were estimated by cutting aboveground biomass. Cattle diet composition was assessed using faeces microhistological analysis. Diet consisted mainly of Poaceae and Cyperaceae species, which decreased in frequency at the end of summer grazing, on the other hand, frequency of woody species including lenga saplings, increased at the same period. Cattle selected grass species in both periods, and also lenga saplings in the end of summer. Livestock is an important economic activity for the inhabitants of the region. This paper provides information that can be for the elaboration of guideline for sustainable coexistence of forest and cattle.Fil: Quinteros, Claudia P.. Centro de Investigación y Extensión Forestal Andino Patagónico (Chubut, Argentina)Fil: Feijóo, Sandra M.. Universidad Nacional de la Patagonia San Juan Bosco. Facultad de Ciencias Naturales. Departamento de BiologíaFil: Arias, Nadia S.. Universidad Nacional de la Patagonia San Juan Bosco. Facultad de Ciencias Naturales. Departamento de BiologíaFil: López Bernal, Pablo M.. Centro de Investigación y Extensión Forestal Andino Patagónico (Chubut, Argentina)Fil: Bava, José O.. Centro de Investigación y Extensión Forestal Andino Patagónico (Chubut, Argentina

Development of a mechanism and an accurate and simple mathematical model for the description of drug release: Application to a relevant example of acetazolamide-controlled release from a bio-inspired elastin-based hydrogel

Producción CientíficaTransversality between mathematical modeling, pharmacology, and materials science is essential in order to achieve controlled-release systems with advanced properties. In this regard, the area of biomaterials provides a platform for the development of depots that are able to achieve controlled release of a drug, whereas pharmacology strives to find new therapeutic molecules and mathematical models have a connecting function, providing a rational understanding by modeling the parameters that influence the release observed. Herein we present a mechanism which, based on reasonable assumptions, explains the experimental data obtained very well. In addition, we have developed a simple and accurate “lumped” kinetics model to correctly fit the experimentally observed drug release behavior. This lumped model allows us to have simple analytic solutions for the mass and rate of drug release as a function of time without limitations of time or mass of drug released, which represents an important step-forward in the area of in vitro drug delivery when compared to the current state of the art in mathematical modeling. As an example, we applied the mechanism and model to the release data for acetazolamide from a recombinant polymer. Both materials were selected because of a need to develop a suitable ophthalmic formulation for the treatment of glaucoma. The in vitro release model proposed herein provides a valuable predictive tool for ensuring product performance and batch-to-batch reproducibility, thus paving the way for the development of further pharmaceutical devices.Este trabajo forma parte de los Proyectos de Investigación financiados por la Comisión Europea a través del Fondo Social Europeo (FSE) y de la Consejería de Educación mediante el Fondo Europeo de Desarrollo Regional (ERDF), el MINECO (Proyectos MAT2013-41723-R, MAT2013-42473-R, PRI−PIBAR-2011-1403 y MAT2012-38043), la Junta de Castilla y León (Proyectos VA155A12, VA152A12, and VA244U13), el CIBER-BBN y el Instituto de Salud Carlos III mediante el Centro de Medicina Regenerativa y Terapia Celular de Castilla y León

Transient magnetic domain wall ac dynamics by means of magneto-optical Kerr effect microscopy

The domain wall response under constant external magnetic fields reveals a complex behavior where sample disorder plays a key role. Furthermore, the response to alternating magnetic fields has only been explored in limited cases and analyzed in terms of the constant field solution. Here we unveil phenomena in the evolution of magnetic domain walls under the application of alternating magnetic fields within the creep regime, well beyond a small fuctuation limit of the domain wall position. Magnetic field pulses were applied in ultra-thin ferromagnetic films with perpendicular anisotropy, and the resulting domain wall evolution was characterized by polar magneto-optical Kerr effect microscopy. Whereas the DC characterization is well predicted by the elastic interface model, striking unexpected features are observed under the application of alternating square pulses: magneto-optical images show that after a transient number of cycles, domain walls evolve toward strongly distorted shapes concomitantly with a modification of domain area. The morphology of domain walls is characterized with a roughness exponent when possible and contrasted with alternative observables which result to be more suitable for the characterization of this transient evolution. The final stationary convergence as well as the underlying physics is discussed.Comment: 9 pages, 8 figure

Evaluation of Natural Technological Interfaces for Children with Psychomotor Disabilities

population with disabilities, there is a group that has intellectual, sensory, motor disabilities, or a combination of them. The International Classification of Functioning, Disability and Health (ICF) defines disability as an umbrella term for impairments, activity limitations and participation restrictions. It is estimated that over 15 % of the world´s population is afflicted by disability in some form. In Argentina this prevalence reaches 7.1%. When these people want to use any technological device, usually find that its physical interfaces are not accessible. Often they need adaptations, raising costs but accessibility is not totally guaranteed. Current technologies allow "more natural" interfaces, where the feedback is immediate. The application of appropriate technology with natural or intuitive interfaces, allow greater accessibility than adaptations commonly used for the overall development of students with psychomotor disorders. The objective of this work is to facilitate the comprehensive development of students with senso psychomotor disorders attending the Special School Beatriz Martinez A. Allio, through the incorporation and implementation of natural interfaces for working with computers in education, offering teaching a complementary tool for the development of their daily activities. The interfaces of hardware and software implementation are proposed to achieve the overall goal. It is intended to make at least a touch screen and at least one interface with the Kinect camera game console Xbox 360.Fil: Beltramone, D. A. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Ingeniería Biomédica; Argentina.Fil: Tula, S. M. Ministerio de Educación de la Provincia de Córdoba. Escuela Especial B. A. Martínez Allio; Argentina.Fil: Rivarola, M. F. Universidad Nacional de Córdoba. Facultad de Ciencias Médicas. Escuela Kinesiología y Fisioterapia; Argentina.Fil: Hidalgo, M. B. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Ingeniería Biomédica; Argentina.Fil: Tancredi, P. D. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Ingeniería Biomédica; Argentina.Fil: Quinteros Quintana, M. L. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Ingeniería Biomédica; Argentina.Fil: Diaz, J. M. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Ingeniería Biomédica; Argentina.Fil: Marcotti, A. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Ingeniería Biomédica; Argentina.Fil: Atea, J. J. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas, Físicas y Naturales. Departamento de Electrónica; Argentina.Ingeniería Médic

Comparative analysis of MIS capacitance structures with high-k dielectrics under gamma, 16O and p Radiation

MIS capacitance structures, with Hafnium Oxide, Alumina and nanolaminate as dielectrics were studied under gamma photons Co, 25 MeV oxygen ions and 10 MeV protons radiation using capacitance-voltage (C-V) characterization. The main trend of the results shows that the nanolaminates stack presents the highest levels of hysteresis and stretch-out of the C-V curves, suggesting that interface layers between dielectrics could play a relevant role in the study of the radiation response.Fil: Quinteros, C. P.. Comisión Nacional de Energía Atómica; ArgentinaFil: Sambuco Salomone, Lucas Ignacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires; ArgentinaFil: Redin, Eduardo Gabriel. Universidad de Buenos Aires; ArgentinaFil: Rafí, J. M.. Consejo Superior de Investigaciones Científicas; EspañaFil: Zabala, M.. Consejo Superior de Investigaciones Científicas; EspañaFil: Faigón, A.. Universidad de Buenos Aires; ArgentinaFil: Palumbo, Félix Roberto Mario. Comisión Nacional de Energía Atómica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Campabadal, F.. Consejo Superior de Investigaciones Científicas; Españ