33 research outputs found

    La vegetación riparia en Sierra Nevada. I: La cuenca alta del río Genil, Catenas edáficas

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    Se realiza una síntesis de las catenas edáficas reconocidas en la cuenca alta del río Genil, incluyendo tres láminas y un mapa de localización geográfica del área estudiada.A synthesis of edafiques sequences recognized at the high basin of river Genil is realized encluding three prints and map of geographic localitation of area studied

    Los cultivos de la cuenca alta del río Genil: relaciones con la bioclimatología y la vegetación potencial

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    En esta nota se recogen nuestras observaciones sobre el aprovechamiento agropecuario de la cuenca alta del río Genil, en relación con los pisos bioclimáticos existentes y las distintas formaciones clímax.lo this papel' we afford sorne remarks about the farming develbpment of natural resources in the high basin of Genil river (Sierra Nevada. Spain), in relation to the bioclimatic taged and the c1imax vegetation

    Los cultivos de la cuenca alta del río Genil: relaciones con la bioclimatología y la vegetación potencial

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    ln this paper we afford sorne remarks about the farming development of natural resources in the high basin of Genil river (Sierra Nevada. Spain), in relation to the bioclimatic taged and the climax vegetation.En esta nota se recogen nuestras observaciones sobre el aprovechamiento agropecuario de la cuenca alta del río Genil, en relación con los pisos bioclimáticos existentes y las distintas formaciones clímax

    La vegetación riparia en Sierra Nevada. I: La cuenca alta del río Genil, Catenas edáficas

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    A synthesis of edafiques sequences recognized at the high basin of river Genil is realized encluding three prints and map of geographic localitation of area studied.Se realiza una síntesis de las catenas edáficas reconocidas en la cuenca alta del río Genil, incluyendo tres láminas y un mapa de localización geográfica del área estudiada

    Cyclophosphamide Chemotherapy Sensitizes Tumor Cells to TRAIL-Dependent CD8 T Cell-Mediated Immune Attack Resulting in Suppression of Tumor Growth

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    Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to generate anti-tumor immune responses in the context of chemotherapy. Methods and Findings: We used a mouse model of malignant mesothelioma, AB1-HA, to investigate T cell-dependent tumor resolution after chemotherapy. Established AB1-HA tumors were cured by a single dose of cyclophosphamide in a CD8 T cell- and NK cell-dependent manner. This treatment was associated with an IFN-α/β response and a profound negative impact on the anti-tumor and total CD8 T cell responses. Despite this negative effect, CD8 T cells were essential for curative responses. The important effector molecules used by the anti-tumor immune response included IFN-γ and TRAIL. The importance of TRAIL was supported by experiments in nude mice where the lack of functional T cells could be compensated by agonistic anti-TRAIL-receptor (DR5) antibodies. Conclusion: The data support a model in which chemotherapy sensitizes tumor cells for T cell-, and possibly NK cell-, mediated apoptosis. A key role of tumor cell sensitization to immune attack is supported by the role of TRAIL in tumor resolution and explains the paradox of successful CD8 T cell-dependent anti-tumor responses in the absence of CD8 T cell expansion

    Studies on the relationship between characteristics of ram semen and fertility / by Pablo Ignacio Quintana Casares.

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    Includes bibliographical references (leaves 274-316)xxii, 333 leaves : ill. (chiefly col.) ; 30 cm.Examines several aspects of male reproduction in the sheep, and how these are related to fertility in the female when semen is introduced by natural mating or artificial insemination.Thesis (Ph.D.)--University of Adelaide, Dept. of Animal Sciences, 199

    Ram sperm motility after intermittent scrotal insulation evaluated by manual and computer-assisted methods

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    © 2006, Asian Journal of Andrology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences. All rights reserved.To study whether additional measurements of motility characteristics of spermatozoa by computer assisted semen analysis (CASA) were more sensitive indicators of reduced semen quality than estimates of percentages of motile, rapid or progressive cells. Methods: Intermittent scrotal insulation was applied to 6 rams for 16 h per day for 21 days or to 2 of these for 12 h per day for 28 days in the following year. Semen was collected and evaluated by CASA immediately and either frozen or stored at 30°C or 5°C before re-evaluation. Results: Intermittent scrotal insulation caused falls in the percentage of motile, progressive and rapid sperm, as did freezing-thawing and storage at 30°C or 5°C. Motility characteristics (amplitude of lateral head displacement, mean path velocity, mean progressive velocity and curvilinear velocity), as determined by CASA fell only when the percentage of motile sperm was already reduced. Freezing and thawing or liquid storage of the semen from insulated rams caused a greater fall in the percentage of motile and rapid sperm than control semen, but only affected the motility characteristics when the percentage of motile sperm was already reduced. Conclusion: Intermittent scrotal insulation affected not only the motility of the freshly collected sperm, but also their ability to withstand the additional stress of storage. The additional data on motility characteristics obtained by CASA appeared to be no more a sensitive indicator than the percentage of motile cells of reductions in semen quality
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