1,511 research outputs found

    Exile: A collection of short stories

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    These stories follow the lives of people, many of whom are expatriates, living in Spain and the United States. The stories take place in no specific period, no determinable place. Except for Humera and Pozuelo, two adjacent towns outside Madrid, the locales are completely fictional

    Using Molecular Markers to Help Predict Who Will Fail after Radical Prostatectomy

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    Recent phase III trial data clearly demonstrate that adjuvant therapy can reduce recurrence and increase survival after prostatectomy for prostate cancer. There is great interest in being able to accurately predict who is at risk of failure to avoid treating those who may not benefit. The standard markers consisting of prostate specific antigen (PSA), Gleason score, and pathological stage are not very specific, so there is an unmet need for other markers to aid in prognostic stratification. Numerous studies have been conducted with various markers and more recently gene signatures, but it is unclear whether any of them are really useful. We conducted a comprehensive review of the literature to determine the current status of molecular markers in predicting outcome after radical prostatectomy

    Heat transfer characteristics of non-Newtonian suspensions

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    This project was undertaken to collect additional information on the heat transfer coefficients of pseudo-plastic suspensions and to test the exponents of the equation of Salamone (12). Using the same equation as derived by Salamone by dimensional analysis, a better correlation of this data was obtained by changing some of the exponents to give the following equation: LD/Kf=0.346(Dvp/M`)0.7(CfM`/Kf)0.72(Ds/D)0.15(Cs/Cf)0.35(ks/kf)0.08 (1) The authors believe that a better correlation is possible and that additional data should be collected on a greater variety of solids in suspension over a large range of Reynolds Numbers

    Prototype Vent Gas Heat Exchanger for Exploration EVA - Performance and Manufacturing Characteristics

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    NASA is developing new portable life support system (PLSS) technologies, which it is demonstrating in an unmanned ground based prototype unit called PLSS 2.0. One set of technologies within the PLSS provides suitable ventilation to an astronaut while on an EVA. A new component within the ventilation gas loop is a liquid-to-gas heat exchanger to transfer excess heat from the gas to the thermal control system's liquid coolant loop. A unique bench top prototype heat exchanger was built and tested for use in PLSS 2.0. The heat exchanger was designed as a counter-flow, compact plate fin type using stainless steel. Its design was based on previous compact heat exchangers manufactured by United Technologies Aerospace Systems, but was half the size of any previous heat exchanger model and one third the size of previous liquid-to-gas heat exchangers. The prototype heat exchanger was less than 40 cubic inches and weighed 2.6 lb. The water side and gas side pressure drops were 0.8 psid and 0.5 inches of water, respectively. Performance of the heat exchanger at the nominal pressure of 4.1 psia was measured at 94%, while a gas inlet pressure of 25 psia resulted in an effectiveness of 84%. These results compared well with the model, which was scaled for the small size. Modeling of certain phenomena that affect performance, such as flow distribution in the headers was particularly difficult due to the small size of the heat exchanger. Data from the tests has confirmed the correction factors that were used in these parts of the model

    MaGICC-WDM: the effects of warm dark matter in hydrodynamical simulations of disc galaxy formation

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    We study the effect of warm dark matter (WDM) on hydrodynamic simulations of galaxy formation as part of the Making Galaxies in a Cosmological Context (MaGICC) project. We simulate three different galaxies using three WDM candidates of 1, 2 and 5 keV and compare results with pure cold dark matter simulations. WDM slightly reduces star formation and produces less centrally concentrated stellar profiles. These effects are most evident for the 1 keV candidate but almost disappear for mWDM>2m_{\mathrm{WDM}}>2 keV. All simulations form similar stellar discs independent of WDM particle mass. In particular, the disc scale length does not change when WDM is considered. The reduced amount of star formation in the case of 1 keV particles is due to the effects of WDM on merging satellites which are on average less concentrated and less gas rich. The altered satellites cause a reduced starburst during mergers because they trigger weaker disc instabilities in the main galaxy. Nevertheless we show that disc galaxy evolution is much more sensitive to stellar feedback than it is to WDM candidate mass. Overall we find that WDM, especially when restricted to current observational constraints (mWDM>2m_{\mathrm{WDM}}>2 keV), has a minor impact on disc galaxy formation.Comment: 13 pages, 9 figures, 2 tables; minor clarifications added in results section, conclusions unchanged; accepted for publication in MNRA

    Phase Change Material Trade Study: A Comparison Between Wax and Water for Manned Spacecraft

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    Phase change material heat sinks have been recognized as an important tool in optimizing thermal control systems for space exploration vehicles and habitats that must deal with widely varying thermal loads and environments. In order to better focus technology investment in this arena, NASA has supported a trade study with the objective of identifying where the best potential pay-off can be found among identified aqueous and paraffin wax phase change materials and phase change material heat sink design approaches. The study used a representative exploration mission with well understood parameters to support the trade. Additional sensitivity studies were performed to ensure the applicability of study results across varying systems and destinations. Results from the study indicate that replacing a wax PCM heat sink with a water ice PCM heat sink has the potential to decrease the equivalent system mass of the mission s vehicle through a combination of a smaller heat sink and a slight 5% increase in radiator size or the addition of a lightweight heat pump. An evaluation of existing and emerging PCM heat sink technologies indicates that further mass savings should be achievable through continued development of those technologies. The largest mass savings may be realized by eliminating the melting and freezing pressure of wax and water, respectively

    Becoming Someone Different: A Grounded Theory Study of How Nurses Integrate Pregnancy and Full Time Employment

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    In the United States, 40% of the contemporary nursing workforce is comprised of women of childbearing age, 65% of whom are employed full-time. Hence, the likelihood of pregnancy occurring for this population at some point in their employment is high. A holistic exploration of how nurses integrate pregnancy and full-time employment has been lacking. The purpose of this research was to explore how primiparous nurses managed pregnancy and full-time employment. Using a grounded theory approach, nurses who were pregnant and delivered their first baby, while employed full-time on 12-hour work shifts, provided a firsthand account of how they incorporated pregnancy with employment. Nurses, as social actors, experience many interactions in their workplace environment. The basic social process, becoming someone different, emerged to explain those interactions and allowed a substantive grounded theory to be developed. From that exploration, the researcher will present the basic social process, becoming someone different, and the four core categories that arose from the analysis: 1) looking different, feeling different – to explain how the physical and emotional changes of pregnancy result in nurses looking and feeling differently about themselves as nurses; 2) expectations while expecting – where the nurse, with previous experiences and ideas about what is expected of her and what she expects from others, changes how she sees herself, based upon her interactions in the workplace with her peers and coworkers; 3) connecting differently – explains how the nurse, while pregnant, develops new relationships and interactions with the people in her environment, specifically her peers, coworkers and patients, and 4) transitioning labor – where, despite challenges from interactions within the workplace from coworkers or tasks, the participant nurses began to focus on their eventual maternity leave and working as long as possible up to the time of delivery in order to prolong that maternity leave

    Portable Life Support System 2.5 Fan Design and Development

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    NASA is building a high-fidelity prototype of an advanced Portable Life Support System (PLSS) as part of the Advanced Exploration Systems Program. This new PLSS, designated as PLSS 2.5, will advance component technologies and systems knowledge to inform a future flight program. The oxygen ventilation loop of its predecessor, PLSS 2.0, was driven by a centrifugal fan developed using specifications from the Constellation Program. PLSS technology and system parameters have matured to the point where the existing fan will not perform adequately for the new prototype. In addition, areas of potential improvement were identified with the PLSS 2.0 fan that could be addressed in a new design. As a result, a new fan was designed and tested for the PLSS 2.5. The PLSS 2.5 fan is a derivative of the one used in PLSS 2.0, and it uses the same nonmetallic, canned motor, with a larger volute and impeller to meet the higher pressure drop requirements of the PLSS 2.5 ventilation loop. The larger impeller allows it to operate at rotational speeds that are matched to rolling element bearings, and which create reasonably low impeller tip speeds consistent with prior, oxygen-rated fans. Development of the fan also considered a shrouded impeller design that could allow larger clearances for greater oxygen safety, assembly tolerances and particle ingestion. This paper discusses the design, manufacturing and performance testing of the new fans

    Braze Development of Graphite Fiber for Use in Phase Change Material Heat Sinks

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    Hamilton Sundstrand (HS), together with NASA Johnson Space Center, developed methods to metallurgically join graphite fiber to aluminum. The goal of the effort was to demonstrate improved thermal conductance, tensile strength and manufacturability compared to existing epoxy bonded techniques. These improvements have the potential to increase the performance and robustness of phase change material heat sinks that use graphite fibers as an interstitial material. Initial work focused on evaluating joining techniques from 4 suppliers, each consisting of a metallization step followed by brazing or soldering of one inch square blocks of Fibercore graphite fiber material to aluminum end sheets. Results matched the strength and thermal conductance of the epoxy bonded control samples, so two suppliers were down-selected for a second round of braze development. The second round of braze samples had up to a 300% increase in strength and up to a 132% increase in thermal conductance over the bonded samples. However, scalability and repeatability proved to be significant hurdles with the metallization approach. An alternative approach was pursued which used nickel and active braze allows to prepare the carbon fibers for joining with aluminum. This approach was repeatable and scalable with improved strength and thermal conductance when compared with epoxy bonding

    A Stirling Encounter with Harmonic Numbers

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