492 research outputs found
The Construction and (Re)Construction of Mentoring Relations, Conversations, Observations and Cameras
The purpose of this study is to better understand mentoring as a relational process. Employing a constructionist form of Action Research called âAppreciative Inquiryâ (AI), twelve teachers, six pairs of Mentors and Newly Qualified Teachers explored through their joint actions with a digital camera, alternative forms of âobservationâ and âfeedbackâ practices. The study took a fresh theoretical approach to mentoring, enabling the teachers to focus on the âpositiveâ aspects of their mentoring experiences. This approach provided constructionist tools with which to analyse the teachersâ experiences. These included âjoint actionâ (Shotter, 1993); the application of âin-vivoâ and âvaluesâ coding (Saldana, 2009) and a form of discourse analysis known as âInterpretative Repertoiresâ (Wetherell and Potter, 1988). Emerging themes showed how the teachers developed an understanding of how they co-constructed their observation and feedback practices; developed their teaching identities; and how filming enabled them to see how their practices connected or disconnected them to childrenâs learning; resources; the environment; and to the wider school and beyond. Findings show how co-constructed learning with a digital camera can support the professional development of both Mentors and Newly Qualified Teachers as part of the induction process, through everyday local mentoring practices. It also shows how mentoring practices can be more effectively aligned with the GTCS (2012) Standards. This small co-study addresses issues raised in key âpolicyâ texts shaping mentoring practices in Scottish education. For these continue to highlight the need for coherence in the language of âmentoringâ; how âfeedbackâ might be more productive in supporting Newly Qualified Teachers; how training for Mentors is required and how pedagogical skills might be enhanced through the Mentoring Process (Evaluation of Teaching Scotlandâs Future, Scottish Government, March 2016)
Ovarian Activity and Oestrous Signs among Group-Housed, Lactating Sows: Influence of Behaviour, Environment and Production
Animal welfare concerns require the development of housing systems that allow the animals to express their natural behaviour. One example of this is the group-housing system for lactating sows. The present study aimed at exploring ovarian activity in such a system. Thirty-eight sows farrowing individually outdoors during spring and summer, and indoors during autumn and winter, and group-housed in groups of four during weeks 3â7 of the lactation period, were monitored regarding reproductive functions, behaviour and production during their first to fourth lactation period. Average ovulation frequency during lactation was 47%. Only 50% of these ovulating cases were accompanied by a standing oestrus. Lactational ovulation frequency was higher in later parities (p < 0.001). Ovulation frequency was higher (p < 0.05) during winter (74%) and spring (69%), than during summer (10%) and autumn (23%). Occurrence of lactational ovulation was associated with some aspects of suckling behaviour and also with litter weight gain (p < 0.05). Forty-nine per cent of the lactational ovulations occurred during the seventh week of lactation. Timing of ovulation seemed positively (p = 0.08) associated with weight loss during lactation. Compared with the sows that were anoestrus during lactation, oestradiol-17ÎČ values were higher (p < 0.05) only in the week before occurrence of lactational ovulation. Weaning-to-oestrous interval was prolonged (p < 0.05) among the sows that ovulated during lactation. The present study identifies several factors influencing ovarian activity among group-housed sows, thereby providing tools for the control of lactational ovulation in group-housing systems
Glycosylation spectral signatures for glioma grade discrimination using Raman spectroscopy
Abstract Background Gliomas are the most common brain tumours with the high-grade glioblastoma representing the most aggressive and lethal form. Currently, there is a lack of specific glioma biomarkers that would aid tumour subtyping and minimally invasive early diagnosis. Aberrant glycosylation is an important post-translational modification in cancer and is implicated in glioma progression. Raman spectroscopy (RS), a vibrational spectroscopic label-free technique, has already shown promise in cancer diagnostics. Methods RS was combined with machine learning to discriminate glioma grades. Raman spectral signatures of glycosylation patterns were used in serum samples and fixed tissue biopsy samples, as well as in single cells and spheroids. Results Glioma grades in fixed tissue patient samples and serum were discriminated with high accuracy. Discrimination between higher malignant glioma grades (III and IV) was achieved with high accuracy in tissue, serum, and cellular models using single cells and spheroids. Biomolecular changes were assigned to alterations in glycosylation corroborated by analysing glycan standards and other changes such as carotenoid antioxidant content. Conclusion RS combined with machine learning could pave the way for more objective and less invasive grading of glioma patients, serving as a useful tool to facilitate glioma diagnosis and delineate biomolecular glioma progression changes
Thermoremanence acquisition and demagnetization for titanomagnetite under lithospheric pressures
©2017. American Geophysical Union.The geological sources of large-scale lithospheric magnetic field anomalies are poorly constrained. Understanding the magnetic behavior of rocks and minerals under the pressures and temperatures encountered at large crustal depths is particularly important in that task. The impact of lithospheric pressure is not well known and most of the time neglected in numerical models of the geological sources of magnetic anomalies. We present thermal remanent magnetization (TRM) acquisition and stepwise thermal demagnetization on synthetic titanomagnetite dispersed powder, within an amagnetic cell under hydrostatic pressure up to 1 GPa. TRM is measured after thermal cycling within a cryogenic magnetometer. Pressure-dependent increase in the Curie temperature (initially in the 50-70°C range) is observed, mostly between 0.3 and 0.6 GPa, on the order of 20 K/GPa. TRM intensity also increases with pressure up to 200% at 675 MPa, although the pressure variation with temperature inside the cell complicates the interpretation
The effect of hydrostatic pressure up to 1.61 GPa on the Morin transition of hematite-bearing rocks: Implications for planetary crustal magnetization
© 2015. American Geophysical Union. All Rights Reserved. We present new experimental data on the dependence of the Morin transition temperature (TM) on hydrostatic pressure up to 1.61 GPa, obtained on a well-characterized multidomain hematite-bearing sample from a banded iron formation. We used a nonmagnetic high-pressure cell for pressure application and a Superconducting Quantum Interference Device magnetometer to measure the isothermal remanent magnetization (IRM) under pressure on warming from 243 K to room temperature (T0). IRM imparted at T0 under pressure in 270 mT magnetic field (IRM270mT) is not recovered after a cooling-warming cycle. Memory effect under pressure was quantified as IRM recovery decrease of 10%/GPa. TM, determined on warming, reaches T0 under hydrostatic pressure 1.38-1.61 GPa. The pressure dependence of TM up to 1.61 GPa is positive and essentially linear with a slope dTM/dP = (25 ± 2) K/GPa. This estimate is more precise than previous ones and allows quantifying the effect of a pressure wave on the upper crust magnetization, with special emphasis on Mars
New Integrated High-Resolution Dinoflagellate Cyst Stratigraphy and Litho- and Chemostratigraphy from the Paris and DieppeâHampshire Basins for the âSparnacianâ
The Paris Basin represents an historical cradle of Palaeogene stratigraphy, where during the nineteenth century the Palaeocene Series and the âSparnacian Stageâ were established. As highlighted by Aubry et al. (2005), whereas the chronostratigraphic connotation of the âSparnacian Stageâ has been controversial since its definition, modern studies of the late Palaeoceneâearly Eocene interval have revealed that the so-called âSparnacianâ deposits encompass a remarkable and short (~170 kyr) episode of the Cenozoic, the PalaeoceneâEocene Thermal Maximum (PETM, ~55.8â55.6 Ma). Dinoflagellate assemblages from the âSparnacianâ of the DieppeâHampshire and Paris basins do not contain the key species Apectodinium augustum, whereas it is present in the northern Belgian Basin Tienen Formation and is coeval there with the CIE and the Apectodinium acme interval. However, our calibration of the Apectodinium acme to the CIE in the DieppeâHampshire and Paris basins suggests its attribution to the A. augustum zone. The absence of species A. augustum in the AngloâParis Basin may be explained by its restriction to more offshore conditions
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