131 research outputs found

    Accompagnement virtuel personnalisé: motivation et réussite scolaire

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    Titre de l'Ă©cran-titre (visionnĂ© le 21 juin 2007)Également disponible en format papierMĂ©diagraphi

    Accompagnement virtuel personnalisé motivation et réussite scolaire : rapport de recherche PREP /

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    Titre de l'Ă©cran-titre (visionnĂ© le 21 juin 2007)Également disponible en format papierMĂ©diagraphi

    Multiframe Scene Flow with Piecewise Rigid Motion

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    We introduce a novel multiframe scene flow approach that jointly optimizes the consistency of the patch appearances and their local rigid motions from RGB-D image sequences. In contrast to the competing methods, we take advantage of an oversegmentation of the reference frame and robust optimization techniques. We formulate scene flow recovery as a global non-linear least squares problem which is iteratively solved by a damped Gauss-Newton approach. As a result, we obtain a qualitatively new level of accuracy in RGB-D based scene flow estimation which can potentially run in real-time. Our method can handle challenging cases with rigid, piecewise rigid, articulated and moderate non-rigid motion, and does not rely on prior knowledge about the types of motions and deformations. Extensive experiments on synthetic and real data show that our method outperforms state-of-the-art.Comment: International Conference on 3D Vision (3DV), Qingdao, China, October 201

    Rock magnetic investigation of possible sources of the Bangui magnetic anomaly

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    International audienceThe Bangui magnetic anomaly (BMA) is the largest lithospheric magnetic field anomaly on Earth at low latitudes. Previous studies investigated its geological source using constraints from satellite and ground magnetic field measurements, as well as from surface magnetic susceptibility measurements on rocks from the Panafrican Mobile Belt Zone (PMBZ). Here we combine magnetic field data modelling and rock magnetic property measurements (susceptibility and natural remanent magnetization, NRM) on many samples from this PMBZ and the surrounding formations. It reveals that NRM is a significant component of the total magnetization (Mt) of the BMA source, which reaches 4.3 A/m with maximum thicknesses of 38 and 54 km beneath the western and eastern parts of the BMA. Only the isolated and relatively thin banded iron formations and some migmatites show such Mt values. Thus we suggest that the thick BMA source may be composed either by overlapped slices of such metamorphic rocks, or by an iron-rich mafic source, or by a combination of these two geological structures

    Final Report on the Consequences of LHC Civil Engineering for the SPS and LEP

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    The excavation of the shafts and caverns for the ATLAS and CMS experiments and the transfer lines between the SPS and LHC will start whilst LEP and the SPS are running. This will be during a period when LEP should be at its peak performance and the SPS will be providing beams for LEP, fixed target physics and LHC test beams. Simulations show that movements of the machine tunnels can be expected during the excavation and it is essential that this does not affect the performance of the SPS and LEP. The predicted movements are of sufficient amplitude to prevent machine operation if no precautions are taken. This report contains the conclusions of the working group which has been studying these problems

    A fiber-modified adenoviral vector interacts with immunoevasion molecules of the B7 family at the surface of murine leukemia cells derived from dormant tumors

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    Tumor cells can escape the immune system by overexpressing molecules of the B7 family, e.g. B7-H1 (PD-L1 or CD86), which suppresses the anti-tumor T-cell responses through binding to the PD-1 receptor, and similarly for B7.1 (CD80), through binding to CTLA-4. Moreover, direct interactions between B7-H1 and B7.1 molecules are also likely to participate in the immunoevasion mechanism. In this study, we used a mouse model of tumor dormancy, DA1-3b leukemia cells. We previously showed that a minor population of DA1-3b cells persists in equilibrium with the immune system for long periods of time, and that the levels of surface expression of B7-H1 and B7.1 molecules correlates with the dormancy time. We found that leukemia cells DA1-3b/d365 cells, which derived from long-term dormant tumors and overexpressed B7-H1 and B7.1 molecules, were highly permissive to Ad5FB4, a human adenovirus serotype 5 (Ad5) vector pseudotyped with chimeric human-bovine fibers. Both B7-H1 and B7.1 were required for Ad5FB4-cell binding and entry, since (i) siRNA silencing of one or the other B7 gene transcript resulted in a net decrease in the cell binding and Ad5FB4-mediated transduction of DA1-3b/d365; and (ii) plasmid-directed expression of B7.1 and B7-H1 proteins conferred to Ad5FB4-refractory human cells a full permissiveness to this vector. Binding data and flow cytometry analysis suggested that B7.1 and B7-H1 molecules played different roles in Ad5FB4-mediated transduction of DA1-3b/d365, with B7.1 involved in cell attachment of Ad5FB4, and B7-H1 in Ad5FB4 internalization. BRET analysis showed that B7.1 and B7-H1 formed heterodimeric complexes at the cell surface, and that Ad5FB4 penton, the viral capsomere carrying the fiber projection, could negatively interfere with the formation of B7.1/B7-H1 heterodimers, or modify their conformation. As interactors of B7-H1/B7.1 molecules, Ad5FB4 particles and/or their penton capsomeres represent potential therapeutic agents targeting cancer cells that had developed immunoevasion mechanisms

    Preliminary Report on the Consequences of LHC Civil Engineering for the SPS and LEP

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    The excavation of the shafts and caverns for the ATLAS and CMS experiments of the LHC will start whilst LEP and the SPS are running. This will be at a period when LEP should be at its peak performance and the SPS will be providing beams for LEP, fixed target physics and LHC test beams. Simulations show that movements of the machine tunnels can be expected during the excavation and it is essential that this does not affect the performance of the SPS and LEP. These movements are of sufficient amplitude to prevent machine operation if no precautions are taken. This preliminary report outlines the problems and suggests what actions should be taken to ensure efficient operation of the SPS and LEP during the critical period

    The LHC test string: first operational experience

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    CERN operates the first version of the LHC Test String which consists of one quadrupole and three 10-m twin aperture dipole magnets. An experimental programme aiming at the validation of the LHC systems started in February 1995. During this programme the string has been powered 100 times 35 of which at 12.4 kA or above. The experiments have yielded a number of results some of which, like quench recovery for cryogenics, have modified the design of subsystems of LHC. Others, like controlled helium leaks in the cold bore and quench propagation bewteen magnets, have given a better understanding on the evolution of the phenomena inside a string of superconducting magnets cooled at superfluid helium temperatures. Following the experimental programme, the string will be powered up and powered down in one hour cycles as a fatigue test of the structure thus simulating 20 years of operation of LHC
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