Supporting diamond open access journals: Interest and feasibility of direct funding mechanisms

As Article Processing Charges (APC) has been a growing concern in academia and policy making, the need for a model where both authors and readers do not pay – the so-called Diamond, or non-APC model – is regularly called for. However, this call is often combined with questions about its sustainability, particularly in financial terms. To answer this concern, this article explores the practical conditions to implement a direct funding mechanism to Diamond open access journals, that is recurrent money provided by funders to support the publication process. Based on a questionnaire survey sent to more than 1,000 Diamond OA journals, it investigates their financial needs, as well as their capacity to interact with research funding organizations (RFOs). The results are structured around four issues regarding the implementation of a direct funding model. First, most Diamond OA journals already make use of money rather than exclusively relying on support and volunteering. Second, those needs would be fulfilled in the eventuality of a regular income from research funders. Third, under this hypothesis, a vast majority of Diamond OA journals can receive and spend money. Finally, most of these journals could develop funding acknowledgments for each article with the promise of regular income through a direct funding mechanism. The conclusion addresses the challenges that such a recurrent financial stream would spur

A survey on real-time 3D scene reconstruction with SLAM methods in embedded systems

The 3D reconstruction of simultaneous localization and mapping (SLAM) is an important topic in the field for transport systems such as drones, service robots and mobile AR/VR devices. Compared to a point cloud representation, the 3D reconstruction based on meshes and voxels is particularly useful for high-level functions, like obstacle avoidance or interaction with the physical environment. This article reviews the implementation of a visual-based 3D scene reconstruction pipeline on resource-constrained hardware platforms. Real-time performances, memory management and low power consumption are critical for embedded systems. A conventional SLAM pipeline from sensors to 3D reconstruction is described, including the potential use of deep learning. The implementation of advanced functions with limited resources is detailed. Recent systems propose the embedded implementation of 3D reconstruction methods with different granularities. The trade-off between required accuracy and resource consumption for real-time localization and reconstruction is one of the open research questions identified and discussed in this paper

Supporting diamond open access journals. Interest and feasibility of direct funding mechanisms

De plus en plus d’universitaires et de gouvernements considèrent que le modèle de libre accès basé sur l’article est problématique, non seulement en raison des inégalités qu’il génère et renforce, mais aussi parce qu’il est devenu insoutenable et même opposé aux valeurs de libre accès

Polynucleotide phosphorylase has an impact on cell biology of Campylobacter jejuni

Polynucleotide phosphorylase (PNPase), encoded by the pnp gene, is known to degrade mRNA, mediating post-transcriptional regulation and may affect cellular functions. The role of PNPase is pleiotropic. As orthologs of the two major ribonucleases (RNase E and RNase II) of Escherichia coli are missing in the Campylobacter jejuni genome, in the current study the focus has been on the C. jejuni ortholog of PNPase. The effect of PNPase mutation on C. jejuni phenotypes and proteome was investigated. The inactivation of the pnp gene reduced significantly the ability of C. jejuni to adhere and to invade Ht-29 cells. Moreover, the pnp mutant strain exhibited a decrease in C. jejuni swimming ability and chick colonization. To explain effects of PNPase on C. jejuni 81-176 phenotype, the proteome of the pnp mutant and parental strains were compared. Overall, little variation in protein production was observed. Despite the predicted role of PNPase in mRNA regulation, the pnp mutation did not induce profound proteomic changes suggesting that other ribonucleases in C. jejuni might ensure this biological function in the absence of PNPase. Nevertheless, synthesis of proteins which are involved in virulence (LuxS, PEB3), motility (N-acetylneuraminic acid synthetase), stress-response (KatA, DnaK, Hsp90), and translation system (EF-Tu, EF-G) were modified in the pnp mutant strain suggesting a more specific role of PNPase in C. jejuni. In conclusion, PNPase deficiency induces limited but important consequences on C. jejuni biology that could explain swimming limitation, chick colonization delay, and the decrease of cell adhesion/invasion ability

Infected breast milk associated with late-onset and recurrent group B streptococcal infection in neonatal twins: a genetic analysis

The original publication is available at www.springerlink.comInternational audienceAsymptomatic excretion of group B streptococcus (GBS) in breast milk may be an underrecognized cause of neonatal and recurrent infection. We report the case of late-onset and recurrent infection in newborn twins resulting from ingestion of maternal breast milk infected with GBS. Genetic analysis of isolates is equally presented