112 research outputs found

    Transformational Leadership and IS Extended Use-The Mediating Role of Job Autonomy and Moderating Role of IT Innovativeness

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    Drawing upon transformational leadership and job characteristics theory, this study develops a research model to examine the impact mechanism of direct supervisor’s leadership behaviors on employees’ extended use of information systems. A field survey was conducted in China and empirical data was collected from 299 employees from both IT and non-IT industries. Structural equation modelling analysis results suggest that transformational leadership is positively associated with employees’ perception of job autonomy, which in turn promote IS extended use. Specifically, IT innovativeness is identified as a significant moderator that strengthens the relationship between transformational leadership and IS extended use. Theoretical and practical implications are discussed in the final section

    A multiple more accurate Hardy-Littlewood-Polya inequality

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    By introducing multi-parameters and conjugate exponents and using Euler-Maclaurin’s summation formula, we estimate the weight coefficient and prove a multiple more accurate Hardy-Littlewood-Polya (H-L-P) inequality, which is an extension of some earlier published results. We also prove that the constant factor in the new inequality is the best possible, and obtain its equivalent forms

    Knowledge-Driven Semantic Segmentation for Waterway Scene Perception

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    Semantic segmentation as one of the most popular scene perception techniques has been studied for autonomous vehicles. However, deep learning-based solutions rely on the volume and quality of data and knowledge from specific scene might not be incorporated. A novel knowledge-driven semantic segmentation method is proposed for waterway scene perception. Based on the knowledge that water is irregular and dynamically changing, a Life Time of Feature (LToF) detector is designed to distinguish water region from surrounding scene. Using a Bayesian framework, the detector as the likelihood function is combined with U-Net based semantic segmentation to achieve an optimized solution. Finally, two public datasets and typical semantic segmentation networks, FlowNet, DeepLab and DVSNet are selected to evaluate the proposed method. Also, the sensitivity of these methods and ours to dataset is discussed

    Hydrogen jet diffusion modeling by using physics-informed graph neural network and sparsely-distributed sensor data

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    Efficient modeling of jet diffusion during accidental release is critical for operation and maintenance management of hydrogen facilities. Deep learning has proven effective for concentration prediction in gas jet diffusion scenarios. Nonetheless, its reliance on extensive simulations as training data and its potential disregard for physical laws limit its applicability to unseen accidental scenarios. Recently, physics-informed neural networks (PINNs) have emerged to reconstruct spatial information by using data from sparsely-distributed sensors which are easily collected in real-world applications. However, prevailing approaches use the fully-connected neural network as the backbone without considering the spatial dependency of sensor data, which reduces the accuracy of concentration prediction. This study introduces the physics-informed graph deep learning approach (Physic_GNN) for efficient and accurate hydrogen jet diffusion prediction by using sparsely-distributed sensor data. Graph neural network (GNN) is used to model the spatial dependency of such sensor data by using graph nodes at which governing equations describing the physical law of hydrogen jet diffusion are immediately solved. The computed residuals are then applied to constrain the training process. Public experimental data of hydrogen jet is used to compare the accuracy and efficiency between our proposed approach Physic_GNN and state-of-the-art PINN. The results demonstrate our Physic_GNN exhibits higher accuracy and physical consistency of centerline concentration prediction given sparse concentration compared to PINN and more efficient compared to OpenFOAM. The proposed approach enables accurate and robust real-time spatial consequence reconstruction and underlying physical mechanisms analysis by using sparse sensor data

    Retrograde intrarenal surgery with intelligent control of renal pelvic pressure for staghorn calculi: a case report

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    Percutaneous nephrolithotomy is the gold standard treatment for staghorn calculi. However, this study reviews a case of an almost complete removal of staghorn calculi following one session of retrograde intrarenal surgery with intelligent control of renal pelvic pressure (RIRS-ICP). A 45 years-old female patient with an 8.3 × 4.5 cm complete staghorn stone was infected with Proteus mirabilis. Two sensitive antibiotics, piperacillin tazobactam and etimicin, were administered for 3 days. Semirigid 7/8.4 Fr ureteroscope was used to treat the renal pelvis and upper calyceal calculi for 57 min. A 550 μm holmium laser fiber with 2.0 J × 30 Hz was set. Next, a disposable flexible ureteroscope of 8.4 Fr was used to address residual middle and lower calyx stones for 94 min. A 200 μm holmium laser fiber with 1.0 J × 30 Hz was set. The renal pelvis pressure was controlled within 15 mmHg. A 2 mm CT scan on the first postoperative day showed inferior caliceal residue of approximately 1.0 × 0.6 cm. No complications occurred. This suggests that RIRS-ICP is a safe and effective treatment for staghorn calculi

    Trehalose induced drought tolerance in plants: physiological and molecular responses

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    Drought stress is significant abiotic stress that limits crop growth and productivity across the globe. The intensity of drought stress continuously rises due to rapid climate change. Drought-induced alterations in physiological and bio-chemical processes by generating membrane dis-stability, oxidative stress, nutritional imbalance and leading to substantial reduction in growth and productivity. Plants accumulate various osmolytes that protect themselves from abiotic stresses' harmful effects. Trehalose (Tre) is a non-reducing sugar found in multiple microbes ranging from bacteria to yeast and in plants and it possesses an excellent ability to improve drought tolerance. Trehalose appreciably enhanced the plant growth, and counter the drought induced damages by maintaining cellular membranes, plant water relations, stomatal regulation, photosynthetic activities, nutrient uptake, osmolyte accumulation, activating stress proteins and detoxifying the reactive oxygen species (ROS) by strengthening the anti-oxidant system. Therefore, it is essential to understand the mechanism of exogenous and endogenous Tre in mitigating the drought-induced damages and to identify the potential research questions that must be answered in the future. Therefore, to better appraise the potential benefits of Tre in drought tolerance in this review, we discussed the diverse physiological and molecular mechanisms regulated by Tre under drought stress. We have a complete and updated picture on this topic to orientate future research directions on this topic

    Heat-Shock Protein 90 Promotes Nuclear Transport of Herpes Simplex Virus 1 Capsid Protein by Interacting with Acetylated Tubulin

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    Although it is known that inhibitors of heat shock protein 90 (Hsp90) can inhibit herpes simplex virus type 1 (HSV-1) infection, the role of Hsp90 in HSV-1 entry and the antiviral mechanisms of Hsp90 inhibitors remain unclear. In this study, we found that Hsp90 inhibitors have potent antiviral activity against standard or drug-resistant HSV-1 strains and viral gene and protein synthesis are inhibited in an early phase. More detailed studies demonstrated that Hsp90 is upregulated by virus entry and it interacts with virus. Hsp90 knockdown by siRNA or treatment with Hsp90 inhibitors significantly inhibited the nuclear transport of viral capsid protein (ICP5) at the early stage of HSV-1 infection. In contrast, overexpression of Hsp90 restored the nuclear transport that was prevented by the Hsp90 inhibitors, suggesting that Hsp90 is required for nuclear transport of viral capsid protein. Furthermore, HSV-1 infection enhanced acetylation of α-tubulin and Hsp90 interacted with the acetylated α-tubulin, which is suppressed by Hsp90 inhibition. These results demonstrate that Hsp90, by interacting with acetylated α-tubulin, plays a crucial role in viral capsid protein nuclear transport and may provide novel insight into the role of Hsp90 in HSV-1 infection and offer a promising strategy to overcome drug-resistance
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