A novel radial basis function neural network for fault section estimation in transmission network

In this paper, the application of Radial Basis Function Neural Network (RBF NN) to fault section estimation in power systems is addressed. The orthogonal least square algorithm has been extended to optimize the parameters of RBF NN. In order to assess the effectiveness of RBF NN, a classical Back-Propagation Neural Network (BP NN) has been developed to solve the same problem for comparison. Computer test is conducted on a 4-bus test system and the test results show that the RBF NN is quite effective and superior to BP NN in fault section estimation.published_or_final_versio

Study on the anti-cerebral ischemia effect of borneol and its mechanism

Background: Borneol is the processed item from resin of Dryobalanops aromatica Gaertn. f. It can enhance the activity of antioxidant enzymes in brain tissue and reduce inflammatory response by improving the energy metabolism of ischemic brain regions, and thereby reduces brain tissue damage. The objective of this paper was to study the anti-cerebral ischemia effect of borneol and its mechanism.Materials and Methods: The anti-cerebral ischemia effect of borneol was studied by ligation of bilateral common carotid arteries (CCA), and vagus nerves in mice and the acute cerebral ischemia-reperfusion experiment in rats.Results: Compared with the blank and solvent control groups, the borneol low-; medium-; and high-dose groups can significantly prolong the gasping time of mice after decapitation, and extend the survival time of mice after ligation of bilateral CCA, and vagus nerves.Conclusion: Compared with the Xueshuantong injection group, the prolongation of survival time of mice after ligation of bilateral CCA, and vagus nerves was more apparent in the high-dose borneol experimental group; each experimental group can significantly reduce the number of leukocyte infiltration, the number of ICAM-1-positive vessels, as well as the number of TNF-α-positive cells.Conclusion: Borneol has an anti-cerebral ischemia effect.Key words: borneol; cerebral ischemia-reperfusion; IL-1β, TNF-α; ICAM-

Individually Frequency Tunable Dual- and Triple-band Filters in a Single Cavity

© 2013 IEEE. This paper presents a new class of second-order individually and continuously tunable dual- and triple-band bandpass filters in a single metal cavity. Each passband is realized by two identical metal posts. These dual- and triple-band tunable filters are achieved by putting two or three identical sets of metal-post pair in a single metal cavity. Metal screws are co-designed as a part of the metal posts to control their insertion depth inside the cavity. In this way, the resonant frequencies can be continuously controlled and designed at the desired frequency bands. Moreover, the distance between the two metal posts in a post pair can be freely tuned. Thus, the external quality factor (Qe) and coupling coefficient (k) between the adjacent modes can be easily adjusted to meet the specified requirement in synthesis design. At the bottom of the cavity, some grooves are used to extend the tunable frequency range and make the resonant frequency linearly varied with the height of the metal post. The center frequency of each passband can be independently tuned with a frequency range of 0.8-3.2 GHz and tunable ratio of 4. Finally, the continuously tunable dual- and triple-band bandpass filters prototypes with second order response are designed and fabricated, of which each passband can be individually tuned with a large tuning range

Verification of a cable element for cable parametric vibration of one-cable-beam system subject to harmonic excitation and random excitation

Author name used in this publication: You-lin Xu2010-2011 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Investigation of therapeutic efficacy and mechanisms of polysaccharide of dendrobium officinale in alleviating cigarette-induced pulmonary inflammation

Posters: no. 13PS36Dendrobium officinale is a medicinal plant from the Orchidaceae family. It has been listed in the latest edition of the Chinese Pharmacopoeia as medicinal material Dendrobii Officinalis Caulis (Tiepishihu) because of its treatment efficacy. According to the Pharmacopoeia it benefits the stomach, promotes the production of body fluid, nourishes yin and eliminates evil-heat. Consequently it com...published_or_final_versio

Molecular Dynamics Simulations of the Roller Nanoimprint Process: Adhesion and Other Mechanical Characteristics

Molecular dynamics simulations using tight-binding many body potential are carried out to study the roller imprint process of a gold single crystal. The effect of the roller tooth’s taper angle, imprint depth, imprint temperature, and imprint direction on the imprint force, adhesion, stress distribution, and strain are investigated. A two-stage roller imprint process was obtained from an imprint force curve. The two-stage imprint process included the imprint forming with a rapid increase of imprint force and the unloading stage combined with the adhesion stage. The results show that the imprint force and adhesion rapidly increase with decreasing taper angle and increasing imprint depth. The magnitude of the maximum imprint force and the time at which this maximum occurs are proportional to the imprint depth, but independent of the taper angle. In a comparison of the imprint mechanisms with a vertical imprint case, while high stress and strain regions are concentrated below the mold for vertical imprint, they also occur around the mold in the case of roller imprint. The regions were only concentrated on the substrate atoms underneath the mold in vertical imprint. Plastic flow increased with increasing imprint temperature

Male Germ Cell Apoptosis and Epigenetic Histone Modification Induced by Tripterygium wilfordii Hook F

Multiglycosides of Tripterygium wilfordii Hook f (GTW), a Chinese herb-derived medicine used as a remedy for rheumatoid arthritis, are considered to be a reversible anti-fertility drug affecting the mammalian spermatids. However, the mechanism behind this effect is still unknown. To study the possible mechanism behind the impact of GTW on spermatogenesis, we administered 4 groups of 4-week-old male mice with different doses of GTW. We found a dose-dependent decrease in the number of germ cells after 40 days of GTW treatment, and an increase in apoptotic cells from the low-dose to the high-dose group. During this same period the dimethylated level of histone H3 lysine 9 (H3K9me2) in GTW-treated testes germ cells declined. Additionally, spermatogonial stem cells (SSCs) from 6-day-old mice were isolated to evaluate the possible effect of GTW or triptolide on development of SSCs. We found a significantly higher incidence of apoptosis and lower dimethylation level of H3K9me2 in the SSCs of GTW or triptolide treatment than in controls. Thus, these data suggest that the GTW-induced apoptosis might be responsible for the fertility impairment in mice. This damage could be traced back to the early stages of spermatogenesis. GTW also affected the epigenetic modification of H3K9 in spermatogenesis. Molecular dynamics simulation suggested that triptolide and dimethylated or trimethylated H3K9 might have similar interaction mechanisms with EED (embryonic ectoderm development). These candidate activation mechanisms provide the first glimpse into the pathway of GTW-induced gonad toxicity, which is crucial for further research and clinical application

Reversibility of apoptosis in cancer cells

Apoptosis is a cell suicide programme characterised by unique cellular events such as mitochondrial fragmentation and dysfunction, nuclear condensation, cytoplasmic shrinkage and activation of apoptotic protease caspases, and these serve as the noticeable apoptotic markers for the commitment of cell demise. Here, we show that, however, the characterised apoptotic dying cancer cells can regain their normal morphology and proliferate after removal of apoptotic inducers. In addition, we demonstrate that reversibility of apoptosis occurs in various cancer cell lines, and in different apoptotic stimuli. Our findings show that cancer cells can survive after initiation of apoptosis, thereby revealing an unexpected potential escape mechanism of cancer cells from chemotherapy