160 research outputs found
The application of MSWI bottom ash fines in high performance concrete
In this study, the application of municipal solid waste incineration (MSWI) bottom ash fines (0-2 mm) as aggregate in high performance concrete is experimentally evaluated. The characteristics of bottom ash fines (BA) and sand are measured and compared. The bottom ash fines are used as sand replacement in the proportion of 10%, 20% and 30% by mass of sand; the properties of concrete are investigated. The influential factors of MSWI bottom ash fines on concrete properties are analyzed, and the further research orientation is addressed
Compact graphene mode-locked wavelength-tunable erbium-doped fiber lasers: from all anomalous dispersion towards all normal dispersion
Soliton operation and soliton wavelength tuning of erbium-doped fiber lasers
mode locked with atomic layer graphene was experimentally investigated under
various cavity dispersion conditions. It was shown that not only wide range
soliton wavelength tuning but also soltion pulse width variation could be
obtained in the fiber lasers. Our results show that the graphene mode locked
erbium-doped fiber lasers provide a compact, user friendly and low cost
wavelength tunable ultrahsort pulse source
Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)
BACKGROUND:
Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control.
METHODS:
Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights.
FINDINGS:
5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease.
INTERPRETATION:
International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems
Periodicities in the Daily Proton Fluxes from 2011 to 2019 Measured by the Alpha Magnetic Spectrometer on the International Space Station from 1 to 100 GV
We present the precision measurement of the daily proton fluxes in cosmic rays from May 20, 2011 to October 29, 2019 (a total of 2824 days or 114 Bartels rotations) in the rigidity interval from 1 to 100 GV based on 5.5×109 protons collected with the Alpha Magnetic Spectrometer aboard the International Space Station. The proton fluxes exhibit variations on multiple timescales. From 2014 to 2018, we observed recurrent flux variations with a period of 27 days. Shorter periods of 9 days and 13.5 days are observed in 2016. The strength of all three periodicities changes with time and rigidity. The rigidity dependence of the 27-day periodicity is different from the rigidity dependences of 9-day and 13.5-day periods. Unexpectedly, the strength of 9-day and 13.5-day periodicities increases with increasing rigidities up to ∼10 GV and ∼20 GV, respectively. Then the strength of the periodicities decreases with increasing rigidity up to 100 GV.</p
Precision Measurement of the Proton Flux in Primary Cosmic Rays from Rigidity 1 GV to 1.8 TV with the Alpha Magnetic Spectrometer on the International Space Station
A precise measurement of the proton flux in primary cosmic rays with rigidity (momentum/charge) from 1 GV to 1.8 TV is presented based on 300 million events. Knowledge of the rigidity dependence of the proton flux is important in understanding the origin, acceleration, and propagation of cosmic rays. We present the detailed variation with rigidity of the flux spectral index for the first time. The spectral index progressively hardens at high rigidities.</p
The application of MSWI bottom ash fines in high performance concrete
In this study, the application of municipal solid waste incineration (MSWI) bottom ash fines (0-2 mm) as aggregate in high performance concrete is experimentally evaluated. The characteristics of bottom ash fines (BA) and sand are measured and compared. The bottom ash fines are used as sand replacement in the proportion of 10%, 20% and 30% by mass of sand; the properties of concrete are investigated. The influential factors of MSWI bottom ash fines on concrete properties are analyzed, and the further research orientation is addressed
Graphene mode locked ultrafast fiber lasers
10.1117/12.877514Proceedings of SPIE - The International Society for Optical Engineering7914-PSIS
Numerical investigation on ballistic performance of coarse-aggregated layered UHPFRC
The impact resistance of coarse-aggregated layered Ultra-High Performance Fiber Reinforced Concrete (UHPFRC) is investigated numerically with LS-DYNA. The Holmquist Johnson Concrete (HJC) model is employed to describe the dynamic behavior of the UHPFRC, and the effect of the coarse aggregates is reflected in the pressure-compaction relation. Mechanical tests are conducted to obtain the material-related inputs for the numerical model, and ballistic experiments are applied to calibrate the model parameter as well as to validate the simulation results. After valuation, the ballistic histories of the projectile and the penetration processes in the UHPFRC targets are analyzed. Furthermore, the study discusses the effects of the target thickness on the depth of penetration, showing the possibility to replace a thicker single-layered target by a thinner triple-layered one to achieve the same level of protection. Finally, perforation limits of the single- and tripled-layered UHPFRC at different impact velocities are estimated, based on which the ACE formulae are modified to accurately predict the perforation limit of the coarse-aggregated layered UHPFRC. The numerical simulations in this study reveal that the triple-layered target requires fewer dosages of cement and steel fibers in comparison to its single-layered counterpart with the same level of ballistic protection
A new two-party bargaining mechanism
10.1007/s10878-011-9424-0Journal of Combinatorial Optimization251135-163JCOP
GM1 improves neurofascin155 association with lipid rafts and prevents rat brain myelin injury after hypoxia-ischemia
White matter injury characterized by damage to myelin is an important process in hypoxic-ischemic brain damage (HIBD). Because the oligodendrocyte-specific isoform of neurofascin, neurofascin 155 (NF155), and its association with lipid rafts are essential for the establishment and stabilization of the paranodal junction, which is required for tight interaction between myelin and axons, we analyzed the effect of monosialotetrahexosyl ganglioside (GM1) on NF155 expression and its association with lipid rafts after HIBD in Sprague-Dawley rats, weighing 12-15 g, on day 7 post-partum (P7; N = 20 per group). HIBD was induced on P7 and the rats were divided into two groups: one group received an intraperitoneal injection of 50 mg/kg GM1 three times and the other group an injection of saline. There was also a group of 20 sham-operated rats. After sacrifice, the brains of the rats were removed on P30 and studied by immunochemistry, SDS-PAGE, Western blot analysis, and electron microscopy. Staining showed that the saline group had definite rarefaction and fragmentation of brain myelin sheaths, whereas the GM1 group had no obvious structural changes. The GM1 group had 1.9-2.9-fold more GM1 in lipid rafts than the saline group (fraction 3-6; all P < 0.05) and 0.5-2.4-fold higher expression of NF155 in lipid rafts (fraction 3-5; all P < 0.05). Injection of GM1 increased the content of GM1 in lipid rafts as well as NF155 expression and its lipid raft association in HIBD rat brains. GM1 may repair the structure of lipid rafts, promote the association of NF155 (or other important proteins) with lipid rafts, stabilize the structure of paranodes, and eventually prevent myelin sheath damage, suggesting a novel mechanism for its neuroprotective properties
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