1,889 research outputs found

    The Effects of Feedback Sequence on Cognitive Performance

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    The current study tested the effects of feedback sequence on performance on a visual-spatial task. Twenty-three female participants were randomly assigned to one of five feedback sequence conditions which occurred after two consecutive trials of a hole-punch task. The five feedback sequence conditions consisted of positive-positive (i.e., positive feedback followed by positive feedback), positive-negative, negative-positive, negative-negative, and a no-feedback control group. Positive feedback was presented as a 80%-90% accuracy range whereas negative feedback was a 30%-40% accuracy range. Third trial accuracy and completion time were measured as was locus of control via the Internal Control Index (ICI) survey. Analyses revealed an effect of feedback sequence on accuracy, but not on completion time. The no-feedback control group performed with lower accuracy than the negative-negative and positive-positive groups. Locus of control had no effect on performance, either by itself or as an interaction with feedback sequence. Differences in accuracy in the no-feedback group may have occurred due to heightened performance ambiguity in that condition

    Psychology of the normal and subnormal.

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    Cardiac Tamponade During Catheterization of a Dog with Congenital Heart Disease

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    Perforation of the heart, which was confirmed by contrast radiography, occurred during venous cardiac catheterization of a dog. As tamponade developed within the next hour, changing physical signs (progressive muffling of heart sounds and murmur, disappearance of a precordial thrill, fall in blood pressure, and increase in heart rate with a weakening pulse) indicated the need for surgical relief in spite of insignificant fluoroscopic evidence. Treatment by thoracotomy, pericardiotomy, and blood replacement was successful. Evidence of a bidirectional ventricular septal defect and probable pulmonic stenosis was observed in angiocardiograms made an hour after the thoracotomy. The dog was discharged in good condition 12 days later. Examination 3 months later revealed no after effects of the cardiac catheterization and thoracotomy

    Uses of Immersive Virtual Reality Distraction as an adjunct to anesthesia to decrease levels of pain in patients experiencing acute procedural pain: An Evidence-Based Educational Module

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    Background: Virtual reality (VR) is a relatively new technology that has garnered medical researchers\u27 attention. VR is a computer-generated depiction of an immersive environment that can be viewed through a headset.1 This multi-sensory immersion provided by VR hypothetically distracts the patient from pain and can reduce pain levels in patients experiencing pain. Objectives: The purpose of this study is to improve anesthesia provider knowledge on the value of virtual reality and its effects as a distraction to reduce pain levels. A literature review including primary research studies addresses the PICO question: Can immersive virtual reality be used as an adjunct to anesthesia in patients ages 10 through 70 who are experiencing acute procedural pain compared to a pharmacological approach? The literature review is used to provide the educational framework to improve provider knowledge. The overall objective is to increase awareness to improve healthcare outcomes for patients experiencing acute pain Methodology: The primary methodology of the proposed project is to administer an online educational intervention to providers focusing on the benefits of the use of virtual reality as a distraction to reduce pain levels in patients experiencing pain. Pre- and post-assessment surveys will be used to measure the improvement of provider knowledge before and after the intervention. Results: 11,198 studies were identified, nine randomized control studies were included in the review. All nine studies were at high risk of bias in at least one domain. A total of 483 patients experiencing pain participated in the nine studies. Of the ten studies examined, eight of them showed a statically significant decrease in pain level reported than the standard of care. One study showed no difference. The results of the QI project showed there was a gain in knowledge between pre-and post-test assessments. In every question, participants correctly picked the correct answer post-intervention. After participating in the educational module, participants showed increased interest and knowledge in immersive virtual reality. Conclusion: The data in this review suggests that VR may have a place in treating patients experiencing acute pain. The studies presented were heterogeneous. Further research is required to validate findings, establish optimal populations, settings, and determine the cost-efficacy of immersive virtual reality in the treatment of acute pain

    Low-frequency noise reduction of spacecraft structures

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    Low frequency noise reduction of spacecraft structure

    Increasing β-catenin/Wnt3A activity levels drive mechanical strain-induced cell cycle progression through mitosis.

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    Mechanical force and Wnt signaling activate β-catenin-mediated transcription to promote proliferation and tissue expansion. However, it is unknown whether mechanical force and Wnt signaling act independently or synergize to activate β-catenin signaling and cell division. We show that mechanical strain induced Src-dependent phosphorylation of Y654 β-catenin and increased β-catenin-mediated transcription in mammalian MDCK epithelial cells. Under these conditions, cells accumulated in S/G2 (independent of DNA damage) but did not divide. Activating β-catenin through Casein Kinase I inhibition or Wnt3A addition increased β-catenin-mediated transcription and strain-induced accumulation of cells in S/G2. Significantly, only the combination of mechanical strain and Wnt/β-catenin activation triggered cells in S/G2 to divide. These results indicate that strain-induced Src phosphorylation of β-catenin and Wnt-dependent β-catenin stabilization synergize to increase β-catenin-mediated transcription to levels required for mitosis. Thus, local Wnt signaling may fine-tune the effects of global mechanical strain to restrict cell divisions during tissue development and homeostasis
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