3 research outputs found
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Suicide and self-harm in Nigeria: a Patient and Public Involvement (PPI) activity to co-develop learning through play plus culturally adapted manual assisted brief psychological intervention for refugee mothers
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Mental health experiences of mothers in Jos, Nigeria: an interpretative phenomenological analysis
Objectives: There is an increasing mental health disease burden in mothers with infants and young children, especially in low- and middle-income countries such as Nigeria. Children of distressed mothers suffer early-life exposure from the effects of maternal distress which contributes to the risk of physical and mental health problems in their childhood and beyond. This study explored mental health lived experiences of mothers in Jos, Nigeria.
Methods: Purposive and Snowball sampling techniques were adopted, and a total of 40 mothers participated with 8 to 11 participants in one of the four focus group discussions. Participants were between the ages of 18 and 43 years, self-identified as mothers with each having a child between the ages of 3 and 48months. Each focus group lasted approximately 60min and was audio-recorded. Interviews were transcribed verbatim and analysed using interpretative phenomenological analysis.
Results: Three overarching themes emerged from the data set such as (1) experience of persisting psychological distress from the time of labour/birth; (2) cultural practices that influence feelings; and (3) anxiety due to limited knowledge about childcare, access to support and healthy food.
Conclusion: Maternal mental health in Nigeria is under-researched and distressed mothers have limited knowledge about evidence-based early child development. The study recommends developing and testing culturally appropriate parenting interventions in Jos, Nigeria. This is likely to be beneficial for the mother and may also improve child outcomes
Production and efficacy testing of live attenuated and inactivated vaccines against experimental Salmonella Kentucky infection in broiler chickens
Background: Salmonella Kentucky is of great veterinary and public health concern and exhibits the capacities to emerge as the most prominent Salmonella serotype in human disease. The objective of this study is to evaluate the efficacy of prepared live attenuated and inactivated vaccines against experimentally induced salmonellosis caused by S. Kentucky in broiler chickens.
Methods: Field isolate of S. Kentucky was obtained from the National Veterinary Research Institute Vom, Nigeria and used in the preparation of experimental vaccines. Broiler chickens purchased and ascertained to be free of Salmonellae were randomly distributed into three experimental groups of 20 chicks each. Five-bromouracil at a concentration of 1000μg/ml was used in attenuation of S. Kentucky in preparation of the live vaccine and 0.6% formaldehyde was used in inactivation of S. Kentucky for preparation of the inactivated vaccine. Group 1 chicks were immunized with the live vaccine subcutaneously at 0.5ml per bird, group 2 received 1ml of the inactivated vaccine subcutaneously, and group 3 served as unvaccinated/control.
Results: There was 100% faecal inhibition and 100% vaccinal efficacy in broiler chickens immunized with the live vaccine on day 56 of age, and 49.6% faecal inhibition and 82.8% vaccinal efficacy in broiler chickens immunized with the inactivated vaccine on day 56 of age when compared with the unvaccinated control. The vaccinated birds also showed higher antibody (IgY) titre levels from day 21 to day 56 of age (p<0.001) on all sampling days when values were compared with the unvaccinated birds.
Conclusion: The interplay between vaccination protocol that includes administration of live attenuated or inactivated S. Kentucky vaccines and developed antibody (IgY) can reduce intestinal colonization by S. Kentucky and subsequent shedding of the serovar in faeces.
Keywords: Salmonella Kentucky, 5-bromouracil, IgY, Antibody, Vaccin