Identifikasi Pemahaman Siswa Menggunakan Model Peta Konsep Mata Pelajaran Kelistrikan Otomotif pada Kelas XI SMK Teknologi Somba Opu Kabupaten Gowa

Identifikasi Pemahaman Siswa Dengan Menggunakan Evaluasi Model Peta Konsep Mata Pelajaran Kelistrikan Otomotif Pada Siswa Kelas XI SMK Teknologi Somba Opu Kabupaten Gowa. Skripsi. Jurusan Pendidikan Teknik Otomotif, Fakultas Teknik, Universitas Negeri Makassar. Penelitian ini merupakan penelitian ex-post facto dalam bentuk deskriptif yang melibatkan variabel tunggal, yaitu pemahaman yang diidentifikasi dengan cara evaluasi model peta konsep. populasi penelitian ini adalah siswa kelas XI SMK Teknologi Somba Opu Kabupaten Gowa pada tahun pelajaran 2010/2011 sebanyak 120 siswa yang tersebar pada 3 kelas. Sampel yang dipilih secara acak sebanyak 30 siswa. Data dalam penelitian ini dikumpulkan melalui dua cara : Nilai siswa yang diperoleh melalui evaluasi multiple choice sebagai data pembanding dan nilai siswa yang diperoleh melalui evaluasi model peta konsep. Hasil penelitian ini dianalisis menggunakan deskriptif inferential, Selanjutnya data tersebut dideskriptifkan. Berdasarkan hasil analisis data dan pembahasannya dapat disimpulkan bahwa pemahaman kelistrikan otomotif siswa kelas XI SMK Teknologi Somba Opu kabupaten gowa yang diidentifikasi dengan evaluasi multiple choice oleh guru bidang studi berada pada kategori tinggi dengan persentase skor ≥ 43,33% sedangkan identifikasi pemahaman siswa oleh peneliti menggunakan evaluasi model peta konsep berada pada kategori rendah dengan persentase skor ≤ 30,00% dengan siswa yang sama. Melihat hal tersebut maka dapat disimpulkan bahwa evaluasi model peta konsep lebih ideal digunakan dalam mengevaluasi pemahaman konsep siswa karena gambaran pemahaman siswa terlihat pada diagram pemetaan konsep

Potential of Neuraminidase from Pasteurella multocida for Inhibiting Avian Influenza Virus Subtype H9N2 Replication In Ovo

In recent decades, neuraminidase/sialidase-based antivirals have been produced to suppress respiratory viral infections, including avian influenza, which relies on sialic acid as the entry point for viruses into cells. While neuraminidase has been extensively studied as an antiviral agent, numerous neuraminidases still have not been evaluated for their antiviral activities. Among these is NanB neuraminidase derived from Pasteurella multocida, which has received limited research attention. This study aimed to assess the potential of NanB neuraminidase in inhibiting H9N2 avian influenza virus infection in ovo. The research commenced with the molecular re-identification of the H9N2 A/Layer/Indonesia/WestJava-04/17 virus isolate, followed by determining the EID50 through Rapid HA test results. The toxicity of NanB neuraminidase was assessed by administering various doses to embryonated chicken eggs (ECE). The antiviral activity of NanB neuraminidase on ECE was evaluated through challenge tests, including treatment before, during, and after the challenge. The assessment involved monitoring the time of embryo death, virus titer through HA test, and viral copy number via RT-qPCR. The results indicated that the H9N2 virus titers capable of infecting 50% of ECE amounted to 108.83 EID50/mL. A dose of 0.258 U/mL of NanB neuraminidase was found to be toxic, leading to embryo mortality after 48 hours of incubation at 37 ℃, while a non-toxic dose was determined to be 0.129 U/mL. The post-challenge treatment group exhibited the most significant reduction in virus titer in ECE. Notably, NanB neuraminidase derived from P. multocida demonstrated the ability to inhibit H9N2 avian influenza virus infection in the ovo model, with the optimal dosage of 0.129 U/mL. The observed decrease in virus titers in the hemagglutination assay and viral copy number assays suggests that NanB neuraminidase holds promise as a potential antiviral candidate for therapeutic approach

Burden and attitude to resistant and refractory migraine: a survey from the European Headache Federation with the endorsement of the European Migraine & Headache Alliance

Background: New treatments are currently offering new opportunities and challenges in clinical management and research in the migraine field. There is the need of homogenous criteria to identify candidates for treatment escalation as well as of reliable criteria to identify refractoriness to treatment. To overcome those issues, the European Headache Federation (EHF) issued a Consensus document to propose criteria to approach difficult-to-treat migraine patients in a standardized way. The Consensus proposed well-defined criteria for resistant migraine (i.e., patients who do not respond to some treatment but who have residual therapeutic opportunities) and refractory migraine (i.e., patients who still have debilitating migraine despite maximal treatment efforts). The aim of this study was to better understand the perceived impact of resistant and refractory migraine and the attitude of physicians involved in migraine care toward those conditions. Methods: We conducted a web-questionnaire-based cross-sectional international study involving physicians with interest in headache care. Results: There were 277 questionnaires available for analysis. A relevant proportion of participants reported that patients with resistant and refractory migraine were frequently seen in their clinical practice (49.5% for resistant and 28.9% for refractory migraine); percentages were higher when considering only those working in specialized headache centers (75% and 46% respectively). However, many physicians reported low or moderate confidence in managing resistant (8.1% and 43.3%, respectively) and refractory (20.7% and 48.4%, respectively) migraine patients; confidence in treating resistant and refractory migraine patients was different according to the level of care and to the number of patients visited per week. Patients with resistant and refractory migraine were infrequently referred to more specialized centers (12% and 19%, respectively); also in this case, figures were different according to the level of care. Conclusions: This report highlights the clinical relevance of difficult-to-treat migraine and the presence of unmet needs in this field. There is the need of more evidence regarding the management of those patients and clear guidance referring to the organization of care and available opportunities

Proceedings of the 3rd International Conference on Community Engagement and Education for Sustainable Development

This proceeding contains articles on the various ideas of the academic community presented at The 3rd International Conference on Community Engagement and Education for Sustainable Development (ICCEESD 2022) organized by the Universitas Gadjah Mada, Indonesia on 7th-8th December 2022.  ICCEESD is a biannual forum for sharing, benchmarking, and discussing HEI’s activities in developing Education for Sustainable Development towards community engagement. Education for Sustainability as a teaching strategy for resolving community challenges through formal, informal, or non-formal education is expected to benefit from various community service best practices by academics, researchers, and students. The 3rd ICCEESD has “Strengthening Education for Sustainability Towards Better Community Engagement” as its theme this year. It is expected that the 3rd ICCEESD will provide a forum for the presenters and participants to exchange best practices, policies, and conceptual implementation of Education for Sustainability towards better community engagement and explore ideas to address community needs.  Conference Title: 3rd International Conference on Community Engagement and Education for Sustainable DevelopmentConference Theme: Strengthening Education for Sustainability Towards Better Community EngagementConference Acronyms: ICCEESD 2022Conference Date: 7th-8th December 2022Conference Location: Grand Rohan Jogja Yogyakarta, IndonesiaConference Organizer: Universitas Gadjah Mada, Indonesi