HI in Local Group analogs: what does it tell us about galaxy formation?

We present the results of our HI survey of six loose groups of galaxies analogous to the Local Group. The survey was conducted using the Parkes telescope and the Australia Telescope Compact Array to produce a census of all the gas-rich galaxies and potential analogs to the high-velocity clouds (HVCs) within these groups down to M(HI)<10^7 M(sun) as a test of models of galaxy formation. We present the HI mass function and halo mass function for these analogous groups and compare them with the Local Group and other environments. We also demonstrate that our non-detection of HVC analogs in these groups implies that they must have low HI masses and be clustered tightly around galaxies, including around our own Milky Way, and are not distributed throughout the Local Group.Comment: 5 pages, To appear in ESO Astrophysics Symposia: "Groups of Galaxies in the Nearby Universe

Blood-flow characteristics in a terminal basilar tip aneurysm prior to its fatal rupture

BACKGROUND AND PURPOSE: The development and validation of methods to stratify the risk of rupture of cerebral aneurysms is highly desired since current treatment risks can exceed the natural risk of rupture. Because unruptured aneurysms are typically treated before they rupture, it is very difficult to connect the proposed risk indices to the rupture of an individual aneurysm. The purpose of this case study was to analyze the hemodynamic environment of a saccular aneurysm of the terminal morphology sub-type that was imaged just prior to its rupture and to test whether the hemodynamic characteristics would designate this particular aneurysm as at high risk. METHODS: A patient-specific computational fluid dynamics model was constructed from 3D rotational angiography images acquired just hours before the aneurysm ruptured. A pulsatile flow calculation was performed and hemodynamic characteristics previously connected to rupture were analyzed. RESULTS: It was found that the aneurysm had a concentrated inflow stream, small impingement region, complex intra-aneurysmal flow structure, asymmetric flow split from the parent vessel to the aneurysm and daughter branches, and high levels of aneurysmal wall shear stress near the impaction zone. CONCLUSIONS: The hemodynamics characteristics observed in this aneurysm right before its rupture are consistent with previous studies correlating aneurysm rupture and hemodynamic patterns in saccular and terminal aneurysms. This study supports the notion that hemodynamic information may be used to help stratify the rupture risk of cerebral aneurysms

Wall motion estimation in intracranial aneurysms

The quantification of wall motion in cerebral aneurysms is becoming important owing to its potential connection to rupture, and as a way to incorporate the effects of vascular compliance in computational fluid dynamics (CFD) simulations./nMost of papers report values obtained with experimental phantoms, simulated images, or animal models, but the information for real patients is limited. In this paper, we have combined non-rigid registration (IR) with signal processing techniques to measure pulsation in real patients from high frame rate digital subtraction angiography (DSA). We have obtained physiological meaningful waveforms with amplitudes in the/nrange 0mm-0.3mm for a population of 18 patients including ruptured and unruptured aneurysms. Statistically significant differences in pulsation were found according to the rupture status, in agreement with differences in biomechanical properties reported in the literature