Estimation of Performance Indices for the Planning of Sustainable Transportation Systems

In simple words, the objective of this research is the estimation of performance indices for the planning of sustainable transportation systems Sustainability is achieved when the Transportation system, Activity system and Environmental system have all reached minimum and stable levels of quality so that they can continue operating in perpetuity at less than these level

Architecture for an Interactive Motion-based Traffic Simulation Environment

In simple words, the objective of this research is to identify the effect of human behavior on traffic To enhance the traffic simulation modeling realism by involving actual human beings navigating the system along with simulated entities in an immersive environmen

Estimation of Performance Indices for the Planning of Sustainable Transportation Systems

In the context of sustainable transportation systems, previous studies have either focused only on the transportation system or have not used a methodology that enables the treatment of incomplete, vague, and qualitative information associated with the available data. This study proposes a system of systems (SOS) and a fuzzy logic modeling approach. The SOS includes the Transportation, Activity, and Environment systems. The fuzzy logic modeling approach enables the treatment of the vagueness associated with some of the relevant data. Performance Indices (PIs) are computed for each system using a number of performance measures. The PIs illustrate the aggregated performance of each system as well as the interactions among them. The proposed methodology also enables the estimation of a Composite Sustainability Index to summarize the aggregated performance of the overall SOS. Existing data was used to analyze sustainability in the entire United States. The results showed that the Transportation and Activity systems follow a positive trend, with similar periods of growth and contractions; in contrast, the environmental system follows a reverse pattern. The results are intuitive and are associated with a series of historic events, such as depressions in the economy as well as policy changes and regulations

CryoEM structure of the human SLC4A4 sodium-coupled acid-base transporter NBCe1.

Na+-coupled acid-base transporters play essential roles in human biology. Their dysfunction has been linked to cancer, heart, and brain disease. High-resolution structures of mammalian Na+-coupled acid-base transporters are not available. The sodium-bicarbonate cotransporter NBCe1 functions in multiple organs and its mutations cause blindness, abnormal growth and blood chemistry, migraines, and impaired cognitive function. Here, we have determined the structure of the membrane domain dimer of human NBCe1 at 3.9 Å resolution by cryo electron microscopy. Our atomic model and functional mutagenesis revealed the ion accessibility pathway and the ion coordination site, the latter containing residues involved in human disease-causing mutations. We identified a small number of residues within the ion coordination site whose modification transformed NBCe1 into an anion exchanger. Our data suggest that symporters and exchangers utilize comparable transport machinery and that subtle differences in their substrate-binding regions have very significant effects on their transport mode

Animales en la poesía : una selección

RESUMEN : La presente es una antología de poemas sobre animales que hemos decidido llamar así, simplemente, Animales en la poesía, distinto al título de Bestiario, que contemplamos inicialmente, debido a cierta generalización que, bajo ese nombre, se reúne animales de toda índole, incluso aquellos pequeños animales que poco prefiguran un bestiario. Esta designación, justamente, designaría una reunión de bestias y estas están definidas, genéricamente, como animales de cuatro patas; entonces ello desmentiría o se prestaría para equívocos...CONTENIDO : Animales en la poesía. -- Kuyata. -- Poema con caballos rojos. -- Un cruce. -- Insectos en la misa. -- Gato casero. -- El gallinazo gira sobre los árboles. -- La serpiente que danza. -- El dragón azulado. -- A un perro. -- Ciervo. -- Cervatillo. -- Avechucho. -- Necoclí. -- Pez muerto. -- En el bosque, al lado del mar. -- Sobre las colinas. -- La perrita coja. -- El loro. -- Giran, giran. -- Pájaros. -- Cangrejos en el Morrosquillo. -- Garcilla bueyera. -- El burro. -- El gatopájaro. -- Bestia mía. -- Habla la vaca (fragmento). -- Un pueblo de amos... -- La mosca. -- Una avispa sobre el agua. -- Hormiga y faraona. -- Tulipanes rojos. -- La mariposa. -- El armadillo. -- Olvidadas ya la libertad y la floresta. -- Verdor. -- Reciclando. -- Milacos. -- Respuesta al párroco. -- La más pequeña abeja. -- El cóndor. -- La canción de los osos. -- Espíritu de pájaro. -- Aves de mar. -- La sirena. -- Un mono

Comedy about Tsar Boris and Grishka Otrepiev

BG dramatic tex