35 research outputs found
Nitrous oxide as a function of oxygen and archaeal gene abundance in the North Pacific
Natural Environment Research Council (NERC) (NE/E01559X/1)
Π‘ΠΊΠ»Π°Π΄ΠΎΠ²Ρ ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΈ ΠΌΠΎΠ²Π½ΠΎΡ ΠΎΡΠΎΠ±ΠΈΡΡΠΎΡΡΡ Π² ΠΊΠΎΠ½ΡΠ΅ΠΊΡΡΡ ΠΌΡΠΆΠΊΡΠ»ΡΡΡΡΠ½ΠΎΡ ΠΊΠΎΠΌΡΠ½ΡΠΊΠ°ΡΡΡ
Π‘ΡΠ°ΡΡΡ ΠΏΡΠΈΡΠ²ΡΡΠ΅Π½Π° Π°Π½Π°Π»ΡΠ·Ρ ΡΠΊΠ»Π°Π΄ΠΎΠ²ΠΈΡ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΡΠ² ΠΌΠΎΠ²Π½ΠΎΡ ΠΎΡΠΎΠ±ΠΈΡΡΠΎΡΡΡ Π² ΠΊΠΎΠ½ΡΠ΅ΠΊΡΡΡ ΠΌΡΠΆΠΊΡΠ»ΡΡΡΡΠ½ΠΎΡ ΠΊΠΎΠΌΡΠ½ΡΠΊΠ°ΡΡΡ, ΡΡ
Π²Π·Π°ΡΠΌΠΎΠ΄ΡΡ ΡΠ° ΡΡΠ½ΠΊΡΡΠΎΠ½ΡΠ²Π°Π½Π½Ρ Π· ΡΠΎΡΠΊΠΈ Π·ΠΎΡΡ ΠΏΡΠ°Π³ΠΌΠ°ΡΠΈΡΠ½ΠΎΡ ΡΠΏΡΡΠΌΠΎΠ²Π°Π½ΠΎΡΡΡ ΠΌΠΎΠ²Π»Π΅Π½Π½ΡΠ²ΠΎΠ³ΠΎ Π²ΠΏΠ»ΠΈΠ²Ρ. ΠΠ΅ΡΠ°Π»ΡΠ½ΠΎ ΡΠΎΠ·Π³Π»ΡΠ΄Π°ΡΡΡΡΡ ΡΡΠΈ ΡΡΠ²Π½Ρ ΡΡΡΡΠΊΡΡΡΠΈ ΠΌΠΎΠ²Π½ΠΎΡ ΠΎΡΠΎΠ±ΠΈΡΡΠΎΡΡΡ (ΡΡΡΡΠΊΡΡΡΠ½ΠΎ-ΠΌΠΎΠ²Π½ΠΈΠΉ, Π»ΡΠ½Π³Π²ΠΎΠΊΠΎΠ³Π½ΡΡΠΈΠ²Π½ΠΈΠΉ ΡΡ ΠΌΠΎΡΠΈΠ²Π°ΡΡΠΉΠ½ΠΈΠΉ) ΡΠ· Π²ΠΈΠ·Π½Π°ΡΠ΅Π½Π½ΡΠΌ ΡΠΏΠ΅ΡΠΈΡΡΠΊΠΈ ΡΡ
Π½ΡΡ
ΡΠΊΠ»Π°Π΄ΠΎΠ²ΠΈΡ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΡΠ².Π‘ΡΠ°ΡΡΡ ΠΏΠΎΡΠ²ΡΡΠ΅Π½Π° Π°Π½Π°Π»ΠΈΠ·Ρ ΡΠΎΡΡΠ°Π²Π»ΡΡΡΠΈΡ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ² ΡΠ·ΡΠΊΠΎΠ²ΠΎΠΉ Π»ΠΈΡΠ½ΠΎΡΡΠΈ Π² ΠΊΠΎΠ½ΡΠ΅ΠΊΡΡΠ΅ ΠΌΠ΅ΠΆΠΊΡΠ»ΡΡΡΡΠ½ΠΎΠΉ ΠΊΠΎΠΌΠΌΡΠ½ΠΈΠΊΠ°ΡΠΈΠΉ, ΠΈΡ
Π²Π·Π°ΠΈΠΌΠΎΠ΄Π΅ΠΉΡΡΠ²ΠΈΡ ΠΈ ΡΡΠ½ΠΊΡΠΈΠΎΠ½ΠΈΡΠΎΠ²Π°Π½ΠΈΡ Ρ ΡΠΎΡΠΊΠΈ Π·ΡΠ΅Π½ΠΈΡ ΠΏΡΠ°Π³ΠΌΠ°ΡΠΈΡΠ΅ΡΠΊΠΎΠΉ Π½Π°ΠΏΡΠ°Π²Π»Π΅Π½Π½ΠΎΡΡΠΈ ΡΠ΅ΡΠ΅Π²ΠΎΠ³ΠΎ Π²ΠΎΠ·Π΄Π΅ΠΉΡΡΠ²ΠΈΡ. ΠΠ΅ΡΠ°Π»ΡΠ½ΠΎ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ ΡΡΠΈ ΡΡΠΎΠ²Π½Ρ ΡΡΡΡΠΊΡΡΡΡ ΡΠ·ΡΠΊΠΎΠ²ΠΎΠΉ Π»ΠΈΡΠ½ΠΎΡΡΠΈ (ΡΡΡΡΠΊΡΡΡΠ½ΠΎ-ΡΠ·ΡΠΊΠΎΠ²ΠΎΠΉ, Π»ΠΈΠ½Π³Π²ΠΎΠΊΠΎΠ³Π½ΠΈΡΠΈΠ²Π½ΡΠΉ ΠΈ ΠΌΠΎΡΠΈΠ²Π°ΡΠΈΠΎΠ½Π½ΡΠΉ) Ρ ΠΏΠΎΡΠ»Π΅Π΄ΡΡΡΠΈΠΌ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ΠΌ ΡΠΏΠ΅ΡΠΈΡΠΈΠΊΠΈ ΠΈΡ
ΡΠΎΡΡΠ°Π²Π»ΡΡΡΠΈΡ
ΠΊΠΎΠΌΠΏΠΎΠ½Π΅Π½ΡΠΎΠ².The article is dedicated to the linguistic personality constituent components' analysis in terms of cross-cultural communication, their interaction and functioning with the speech influence pragmatic orientation taken into consideration. The three levels of the linguistic personality (that is, structural linguistic, lingo cognitive and motivation ones) are under analysis with the following their constituent components specificity determinatio
Changes in the Expression of Hypothalamic Lipid Sensing Genes in Rat Model of Intrauterine Growth Retardation (IUGR).
Intrauterine growth retardation (IUGR) has been
linked to the development of type 2 diabetes in later life. The
mechanisms underlying this phenomenon are unknown. Recent data
suggest that some of the molecular defects underlying type 2 diabetes
reside in the CNS. The enzyme carnitine palmitoyltransferase-1
(CPT1) regulates long-chain fatty acid (LCFA) entry into mitochondria,
where LCFA undergo -oxidation. Hypothalamic inhibition of
CPT1 decreases food intake and suppresses endogenous glucose
production. Our aim was to investigate the effects of uterine artery
ligation, a procedure that mimics uteroplacental insufficiency, on the
CNS expression of CPT1 and other key enzymes of LCFA metabolism.
Bilateral uterine artery ligation was performed on d 19 of gestation
in the pregnant rat; sham-operated pregnant rats served as controls.
Hypothalamus, cerebellum, hippocampus, and cortex were dissected and
analyzed at birth by real-time PCR. Nonesterified fatty acid (NEFA)
serum levels were significantly higher in IUGR pups (p 0.0001). In
IUGR rats, the hypothalamic expression of CPT1 isoform C (p 0.005)
and acetyl-CoA carboxylase (ACC) isoforms alpha (p 0.05) and beta
(p 0.005) were significantly decreased. The data presented here
support the hypothesis that an abnormal intrauterine milieu can induce
changes in hypothalamic lipid sensing