539 research outputs found
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Introducing creativity techniques and software apps to the care of people with dementia
This poster reports research to introduce creative problem solving techniques and software to the care for people with dementia in residential homes
Pearling: stroke segmentation with crusted pearl strings
We introduce a novel segmentation technique, called Pearling, for the semi-automatic extraction of idealized models of networks of strokes (variable width curves) in images. These networks may for example represent roads in an aerial photograph, vessels in a medical scan, or strokes in a drawing. The operator seeds the process by selecting representative areas of good (stroke interior) and bad colors. Then, the operator may either provide a rough trace through a particular path in the stroke graph or simply pick a starting point (seed) on a stroke and a direction of growth. Pearling computes in realtime the centerlines of the strokes, the bifurcations, and the thickness function along each stroke, hence producing a purified medial axis transform of a desired portion of the stroke graph. No prior segmentation or thresholding is required. Simple gestures may be used to trim or extend the selection or to add branches. The realtime performance and reliability of Pearling results from a novel disk-sampling approach, which traces the strokes by optimizing the positions and radii of a discrete series of disks (pearls) along the stroke. A continuous model is defined through subdivision. By design, the idealized pearl string model is slightly wider than necessary to ensure that it contains the stroke boundary. A narrower core model that fits inside the stroke is computed simultaneously. The difference between the pearl string and its core contains the boundary of the stroke and may be used to capture, compress, visualize, or analyze the raw image data along the stroke boundary
Tourists’ expenditure behaviour: the influence of satisfaction and the dependence of spending categories.
A review of the literature shows that the relationship between satisfaction and tourism expenditure, as well as the dependence among different tourist expenditure categories, are under-researched topics. The aim of this study is twofold: first, to investigate the influence on tourism expenditure of tourists’ satisfaction with the destination, correcting for the effect of some socio-demographic and trip-related variables; second, to study the dependence among tourist expenditure on the different tourist categories that create the overall expenditure for the trip. This study focuses on an analysis of the expenditure behaviour of a sample of international visitors who travelled in an area around the Dolomites in Northern Italy, adopting the doublehurdle model with the Heien and Wessells estimator. In discussing the results, policy implications and managerial issues for tourism destinations are presented
An optimal battery interchange policy for an electric car powered by a mobile solar power station
The World Solar Challenge is a 3000 kilometre race from Darwin to Adelaide, across the Australian continent, for solar powered racing cars. Annesley College accompanied the 2001 event in an electric car powered by batteries. While one battery was used to power the car another was charged from a solar panel carried by a mobile solar power station. When the first battery became empty the batteries were interchanged and the first battery put on charge. The process was repeated throughout the event. In this paper we find a policy for interchanging the batteries that maximises the distance travelled each day
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A software app to support creativity in dementia care
This paper reports a new mobile software app to support creative thinking by carers for people with dementia. The design of the app was informed by both pre-studies that demonstrated the potential of investigating challenging behaviors in non-care domains to improve person-centered care, and a model of creative problem solving adapted to dementia care. The resulting app implements different versions of the Other Worlds creativity technique to generate then reflect on ideas to improve resident care. An evaluation of the app in one residential home revealed that carers were able to use the app as described in the model, and deliver novel care to one resident in the home
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Digital Creativity in Dementia Care Support
This paper reports the application of digital creativity to the care for people with dementia. A digital app
was developed for use by staff in residential homes caring for people with dementia. The app invokes a
set of computational services to undertake creative work, the results of which are presented to encourage
and support cognitive creativity by care staff. The services undertake computational work such as
retrieving resolutions to care problems encountered previously, matching care situations to situations in
analogical domains such as parenting, teaching and prison life, and automatically generating customized
creativity prompts. The app was designed so that care staff can generate contributions to resident care
plans that are novel and hence individualized to the resident as part of a shift towards more person-centred
care
Topical delivery of climbazole to mammalian skin
Dandruff is a common condition, affecting up to half the global population of immunocompetent adults at some time during their lives and it has been highly correlated with the over-expression of the fungus Malassezia spp. Climbazole (CBZ) is used as an antifungal and preservative agent in many marketed formulations for the treatment of dandruff. While the efficacy of CBZ in vitro and in vivo has previously been reported, limited information has been published about the uptake and deposition of CBZ in the skin. Hence, our aim was to investigate the skin permeation of CBZ as well as the influence of various solvents on CBZ skin delivery. Four solvents were selected for the permeability studies of CBZ, namely propylene glycol (PG), octyl salicylate (OSal), Transcutol® P (TC) and polyethylene glycol 200 (PEG). The criteria for selection were based on their wide use as excipients in commercial formulations, their potential to act as skin penetration enhancers and their favourable safety profiles. 1% (w/v) solutions of CBZ were applied under infinite and finite dose conditions using Franz type diffusion cells to human and porcine skin. In line with the topical use of CBZ as an antidandruff agent, comparatively low amounts of CBZ penetrated across the skin barrier ( 7-fold) compared with human skin (p<0.05). Nevertheless, no statistical differences were observed in the amounts that permeated across the different membranes. These preliminary results confirm the potential of simple formulations of CBZ to target the outer layers of the epidermis. The PG and OSal formulations appear to be promising vehicles for CBZ in terms of overall skin extraction and penetration. Future work will expand the range of vehicles studied and explore the reasons underlying the retention of CBZ in the outer layers of the skin
EQ-5D-5L versus 3L: the impact on cost-effectiveness
Objectives To model the relationship between EQ-5D-3L and EQ-5D-5L and examine how differences impact on cost-effectiveness in case studies. Methods We used two datasets that included both EQ-5D-3L and EQ-5D-3L from the same respondents. The EuroQoL dataset (n=3551) included patients with different diseases and a healthy cohort. The National Databank (NDB) dataset included patients with rheumatoid disease (n=5205). We estimated a system of ordinal regressions in each dataset using copula models, to link responses to the 3L instrument to 5L and its tariff, and vice versa. Results were applied to nine cost-effectiveness studies. Results Best-fitting models differed between EuroQoL and NDB datasets in terms of the explanatory variables, copulas and coefficients. In both cases the coefficients of the covariates and latent factor between -3L and -5L were significantly different, indicating that the two instruments are not a uniform realignment of the response levels for most dimensions. In the case studies, moving from 3L to 5L caused a decrease of up to 87% in incremental QALYs gained from effective technologies in almost all cases. ICERs increased, often substantially. Conversely, one technology with a significant mortality gain saw increased incremental QALYs. Conclusion 5L shifts mean utility scores up the utility scale towards full health and compresses them into a smaller range, compared to -3L. Improvements in quality of life are valued less using 5L than with 3L. 3L and 5L can produce substantially different estimates of cost effectiveness. There is no simple proportional adjustment that can be made to reconcile these differences
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