44 research outputs found

    What are the Marital Problems of Happy Couples? A Multimethod, Two‐Sample Investigation

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/162758/2/famp12483.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/162758/1/famp12483_am.pd

    A contextual process model of the associations among family vulnerabilities, life stressors, marital behavior, marital satisfaction, and personal well-being

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    "The association between marital satisfaction and spouses' personal well-being is well established in the family studies and family psychology literatures. Although models specifying the ways in which contextual variables and life stressors influence both marital satisfaction and personal well-being exist in the literature on family studies, no model had been proposed that jointly considered these variables longitudinally. The purpose of the present study was to build on and extend previous theoretical models of marriage and personal well-being to explain (a) the concurrent association between family vulnerabilities, life stressors, and marital behavior; (b) the prospective influence of marital behavior on marital satisfaction; and (c) the prospective impact of one's own marital satisfaction on personal well-being. In addition, the present study addressed previous limitations in the literature by (a) using multiple reporters for the latent constructs under study, (b) using family-level data rather than unrelated samples of husbands and wives, and (c) expanding the conceptualization of personal well-being to include self-reports of depression and life satisfaction as well as observational reports of sadness. Using the first three waves from a study on families with young adolescents (N = 338 couples), partial support was found for the study hypotheses. Results from a series of structural equation models (SEM) suggested that enduring family vulnerabilities, life events, and adaptive processes such as marital behavior exchanges do not exert their influence on spouses' personal well-being through marital satisfaction. Rather, it appears that there is a direct, significant relationship between the contextual variables and personal well-being. Although one's spouses' negative marital behaviors were not significant predictors of marital satisfaction over time, or of change in marital satisfaction, one's own marital satisfaction was predictive of personal well-being over time. Further, change in marital satisfaction was a significant predictor of change in personal well-being. Model pathways were consistent for husbands and wives."--Abstract from author supplied metadata

    Understanding breast cancer patients' preference for two types of exercise training during chemotherapy in an unblinded randomized controlled trial

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    <p>Abstract</p> <p>Background</p> <p>Patient preference for group assignment may affect outcomes in unblinded trials but few studies have attempted to understand such preferences. The purpose of the present study was to examine factors associated with breast cancer patients' preference for two types of exercise training during chemotherapy.</p> <p>Methods</p> <p>Breast cancer patients (N = 242) completed a battery of tests including a questionnaire that assessed patient preference and the theory of planned behavior (TPB) prior to being randomized to usual care, resistance exercise training (RET), or aerobic exercise training (AET).</p> <p>Results</p> <p>99 (40.9%) participants preferred RET, 88 (36.4%) preferred AET, and 55 (22.7%) reported no preference. Past exercisers (p = 0.023), smokers (p = 0.004), and aerobically fitter participants (p = 0.005) were more likely to prefer RET. As hypothesized, participants that preferred AET had more favorable TPB beliefs about AET whereas participants that preferred RET had more favorable TPB beliefs about RET. In multivariate modeling, patient preference for RET versus AET was explained (R<sup>2 </sup>= .46; p < 0.001) by the difference in motivation for RET versus AET (β = .56; p < 0.001), smoking status (β = .13; p = 0.007), and aerobic fitness (β = .12; p = 0.018). Motivational difference between RET versus AET, in turn, was explained (R<sup>2 </sup>= .48; p < 0.001) by differences in instrumental attitude (β = .27; p < 0.001), affective attitude (β = .25; p < 0.001), and perceived behavioral control (β = .24; p < 0.001).</p> <p>Conclusion</p> <p>Breast cancer patients' preference for RET versus AET during chemotherapy was predicted largely by a difference in motivation for each type of exercise which, in turn, was based on differences in their beliefs about the anticipated benefits, enjoyment, and difficulty of performing each type of exercise during chemotherapy. These findings may help explain patient preference effects in unblinded behavioral trials.</p> <p>Trial Registration</p> <p>ClinicalTrials.gov Identifier NCT00115713.</p

    Two Host Factors Regulate Persistence of H7a-Specific T Cells Injected in Tumor-Bearing Mice

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    BACKGROUND: Injection of CD8 T cells primed against immunodominant minor histocompatibility antigens (MiHA) such as H7(a) can eradicate leukemia and solid tumors. To understand why MiHA-targeted T cells have such a potent antitumor effect it is essential to evaluate their in vivo behavior. In the present work, we therefore addressed two specific questions: what is the proliferative dynamics of H7(a)-specifc T cells in tumors, and do H7(a)-specific T cells persist long-term after adoptive transfer? METHODOLOGY/PRINCIPAL FINDINGS: By day 3 after adoptive transfer, we observed a selective infiltration of melanomas by anti-H7(a) T cells. Over the next five days, anti-H7(a) T cells expanded massively in the tumor but not in the spleen. Thus, by day 8 after injection, anti-H7(a) T cells in the tumor had undergone more cell divisions than those in the spleen. These data strongly suggest that anti-H7(a) T cells proliferate preferentially and extensively in the tumors. We also found that two host factors regulated long-term persistence of anti-H7(a) memory T cells: thymic function and expression of H7(a) by host cells. On day 100, anti-H7(a) memory T cells were abundant in euthymic H7(a)-negative (B10.H7(b)) mice, present in low numbers in thymectomized H7(a)-positive (B10) hosts, and undetectable in euthymic H7(a)-positive recipients. CONCLUSIONS/SIGNIFICANCE: Although in general the tumor environment is not propitious to T-cell invasion and expansion, the present work shows that this limitation may be overcome by adoptive transfer of primed CD8 T cells targeted to an immunodominant MiHA (here H7(a)). At least in some cases, prolonged persistence of adoptively transferred T cells may be valuable for prevention of late cancer relapse in adoptive hosts. Our findings therefore suggest that it may be advantageous to target MiHAs with a restricted tissue distribution in order to promote persistence of memory T cells and thereby minimize the risk of cancer recurrence

    Associations Between Social Connectedness, Emotional Well-Being, and Self-Rated Health Among Older Adults: Difference by Relationship Status

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    The present study investigates the association between social connectedness (i.e., social network characteristics, family and friend support, and social ties with neighbors), emotional well-being, and self-rated health and whether these associations differ based on respondents’ relationship status among adults aged 62 and older. A series of multigroup generalized structural equation models (GSEMs) were conducted using data from the National Social, Health, and Aging Project. Social connectedness items were mostly positively associated with emotional well-being and self-rated health, and several of these associations are stronger for older adults who are unpartnered versus those who are cohabiting or married. Cohabiting and married individuals do not appear to have the same associations between social network size, friend support, and emotional well-being compared to unpartnered older adults. The present study lends support for how a variety of social supports are vital for older adults and their well-being

    Unforgiveness, Depression, and Health in Later Life: The Protective Factor of Forgivingness

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    Objectives: Feeling unforgiven by others has been linked to poor health outcomes. The current study examined whether feeling unforgiven by others is associated with depression and self-rated health among older adults in the United States. The potential moderating roles of forgiving others and self-forgiveness in the association between unforgiveness and both depression and self-rated health was also assessed along with gender differences. Method: Data were drawn from a sample of 1009 adults in Wave 2 of the Religion, Aging, and Health Survey, a national sample of adults aged over 67. Depression was measured using the eight item short form from the Center for Epidemiologic Studies-Depression (CES-D) scale. Self-rated health was assessed with a one-item indicator. Results: Analyses indicated that higher levels of self-forgiveness ameliorated the relationship between unforgiveness by others and depression for men and women and higher levels of forgiving others attenuated the association between unforgiveness by others and depression for women. Self-forgiveness was protective of depression for women who reported unforgiveness by others and low levels of forgiving others. Regardless of levels of self-forgiveness, men who were most likely to forgive others experienced a significant association between unforgiveness by others and depression. Neither forgiving others nor the self were significant moderators in the association between unforgiveness and self-rated health. Conclusion: Forgiving others and the self may be protective of well-being when women feel unforgiven by others. These findings have implications for forgiveness intervention programs and contribute to literature pertaining to forgiveness and health in later life

    Stayovers in emerging adulthood: Who stays over and why?

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    Emerging adulthood is an intense period of personal development and interpersonal exploration; most emerging adults engage in several romantic relationships of varying commitment levels throughout their late teens and early twenties. The current study explored whether one relationship behavior, staying over, is related to specific demographic characteristics, previous experiences, and personal beliefs and attitudes. A sample of 627 emerging adults were surveyed about their experiences with staying overnight with their romantic partners, their reasons for doing so, and their attitudes about full-time cohabitation. Participants who were older, had cohabited at some point, lived independently from family, viewed religion as unimportant, and had positive attitudes about cohabitation were found to be more likely to stay over

    Group-Based Trajectory Modeling of Marital Quality: A Critical Review

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    The predominant view in both the research literature and practice is that marital quality declines over time. Although the majority of research using variable-centered approaches such as latent growth curve modeling supports this view, contemporary research using person-centered group-based trajectory modeling techniques suggest a variety of trajectories of marital quality development, including stability, decline, and, occasionally, rebound following decline. The present review synthesizes this current body of research and summarizes the variety of trajectories found across 14 reports examining both positive and negative marital quality dimensions. The theories informing this body of research and the predictors of the various trajectories are also reviewed. We conclude with a discussion of methodological and practical implications of the findings to date and introduce the honeymoon-as-ceiling effect, a phrase we use to capture the consistent finding that marital quality rarely increases beyond its initial value

    Longitudinal Associations Between Formal Volunteering and Cognitive Functioning

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    Objectives The present study examines the association between formal volunteering and cognitive functioning over time. We also examine the moderating roles of race, sex, education, and time. Method Using 11,100 participants aged 51 years and older and nine waves of data from the Health and Retirement Survey, we simultaneously modeled the longitudinal associations between engaging in formal volunteering and changes in cognitive functioning using multilevel models. Results Formal volunteering was associated with higher levels of cognitive functioning over time, especially with aspects of cognitive functioning related to working memory and processing. This association was stronger for women than it was for men, and for those with below average levels of education. The positive association between formal volunteering and cognitive functioning weakened over time when cognitive functioning was conceptualized as memory, but strengthened over time when conceptualized as working memory and processing. Discussion Volunteering is a productive activity that is beneficial not just to society, but to volunteers\u27 levels of cognitive functioning in older age. For women and those with lower levels of education, formal volunteering appears particularly beneficial to working memory and processing
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