Comparision of Different Classifiers for Prediction of Breast Cancer

The cell formed in the  breast are known as breast cancer. It occurs mainly in women and it may occur rarely in men also. It is considered as the most common ailment that can lead to large number of death in females every year. In spite of the factuality that cancer is treatable and can be relieve if treated at its early stages; many patients are screened for cancer only at a very late stage. Data mining technique such as classifications provides an efficient technique to classify data, where these methods are commonly used for diagnostic decision making. The Machine learning techniques propound various methods such as statistical and probabilistic methods which allow system to learn from past experiences to distinguish and identify patterns from a standard dataset. The research work presents a review of machine learning techniques which can be used in breast cancer disease detection by applying algorithms on breast cancer Wisconsin data set.  Algorithms such as Navies Bayes, Random Forest, Support Vector Machine, Adaboost and Decision Trees were used. The result outcome shows that Random Forest performs better than other techniques

Primary oral malignant melanoma - A case report

Melanoma arising from mucosal surfaces of the head and neck is a very rare neoplasm and it is considered among the most deadly of all human neoplasms. Although skin melanomas comprise 1.3% of all cancers, oral malignant melanoma accounts for only 0.2 to 8% of all reported melanomas, common sites of occurrence being palate and maxillary gingiva. Due to its presence at relatively obscure areas in the oral cavity, most oral malignant melanomas are diagnosed at a late stage and are associated with poor prognosis. Early diagnosis is essential for successful treatment and perhaps the key factor in improving the prognosis of oral malignant melanoma. This paper reports a case of a 42year old woman with primary malignant melanoma at a rare site, the left retromolar region involving the left side of the mandible, up to level IV ipsilateral cervical lymph nodes. The patient was treated with left hemimandibulectomy with radical neck dissection and was followed up for two years and 3months without any local recurrence or distant metastasis. It is suggested that any pigmented lesion that are suspected of undergoing changes in their clinical appearance should be biopsied

In-vitro propagation, organic farming and comparative phytochemical evaluation of Curculigo Orchioides Gaertn. (Musali)

Medicinal plants belong to the oldest known health care products that have been used by mankind all over the world in the form of folklore medicine, traditional medicines or ethnic medicines. But due to the over dependence of herbal drug industry on the plant population, wild source became depleted. Several drugs became endangered while some others had been in the verge of extinction. Musali (Curculigo orchioides) is such a plant which is facing a threat of extinction. These plants can be produced by different methods. The main 2 methods for the propagation of plants will come under the following headings viz; Conventional way of propagation and Non-conventional way of propagation (In Vitro propagation). If a small change in climate and temperature is affecting the chemical composition of plants, then obviously there may be chances for change in the same while propagating it through different techniques. In this study the preliminary analytical profile of the three samples were done in order to know whether the organic and In Vitro variety can be replaced with the wild. As Musali (Curculigo orchioides Gaertn.) is a drug used in several formulations and Musali Khadiradi Kashayam is one among the important one used for the reproductive problems. So the formulation also needs to be analysed in order to know whether the variation in cultivation techniques will affect the physicochemical and chromatographic parameters

FORMULATION AND EVALUATION OF EXTENDED RELEASE PELLETS OF PIOGLITAZONE HYDROCHLORIDE USING NATURAL AND SYNTHETIC POLYMERS BY FLUIDIZED BED COATING TECHNIQUE

Objective: The objective of the current work was to develop Pioglitazone hydrochloride (HCl) pellets coated with natural polymer extracted from peas gum and also to compare the drug release profile with coatings containing semi-synthetic and synthetic polymers. Methods: Fluidized bed coating technique was used to develop pellets. A 22 factorial design was employed to study the effect of independent variables (inlet air temperature and spray rate), on dependent variables (percentage entrapment efficiency, percentage friability, and average particle size). Optimization was done by fitting experimental data to the software program. Obtained pellets were subjected to different evaluation parameters which are critical in the development of the dosage form. An in vitro lag phase study was carried out for all batches in simulated gastric fluid (0.1N HCl) for 5 h and in vitro drug release study was carried out for optimized batch (E-2 and P-3) in simulated intestinal fluid (pH 7.4 phosphate buffer). Results: The optimized batches E-2 and P-3 showed satisfactory percentage entrapment efficiency of 92.66±1.52, percentage friability of 0.57±0.03, and average particle size of 1424±16 μm. All batches maintained lag phase for 5 h in 0.1N HCl. An optimized batch of two different sizes exhibited a burst release within 30 min in a simulated intestinal fluid with no significant difference in release rate constant (*p>0.05) and followed first-order kinetics. Conclusion: Thus, Pioglitazone HCl pulsatile pellets were successfully developed for treating diabetes mellitus by fluidized bed coating technique employing factorial design

FABRICATION AND CHARACTERIZATION OF FAST DISSOLVING FILMS OF ECLIPTA PROSTRATE LEAVES EXTRACT TO TREAT MOUTH ULCERS

Objective: This research focused on the design of fast dissolving herbal film of Eclipta Prostrate leaves extract for mouth ulcers. Methods: The extract of Eclipta Prostrata leaves was formulated as films by solvent casting method using various polymers viz., HPMC E5, HPMC E15, sodium alginate and PVA. The films were designed by using propylene glycol as a plasticizer, SSG as super disintegrate and honey as a sweetener. Furthermore, the films were evaluated for thickness, folding endurance, weight variation, % elongation, surface pH, % moisture uptake, % moisture loss, disintegration and in vitro drug release study. Results: The revealed that all the films were good in appearance and had a smooth texture. Out of all ten formulations, F3 and F5 disintegrated rapidly with a disintegration time of 27 and 32 seconds. The drug release studies revealed that all the formulations had a good release profile, but the F3 formulation showed rapid release i.e. 83.57% in 4 min. The stability studies revealed that the formulations F3 and F5 were found good with non-tackiness, easily separable and disintegrated at 29 and 33 sec respectively with no appearance and drug release. Conclusion: The research revealed that Eclipta prostrate leaves extract can be formulated into oral films for the treatment of mouth ulcers with improved bioavailability and expected patient compliance

A Study on Impact of Television Advertising towards the Selection of Branded Women's Apparel with Special Reference to Consumer at Tiruchirappalli City

A Study on the Impact of Television Advertising towards the Selection of Branded Women’s Apparel With special reference to a consumer at Tiruchirappalli City. Television Advertisement assumes a noteworthy job in present-day life. It shapes the states of mind of the general public and the individual and definitely impacts customer behavior. The customer needs to fight with a gigantic measure of data and have the capacity to settle on a decision, reach determinations and settle on critical choices. This examination plans to set up whether the Trichy City, Tamilnadu, customers affects their purchasing choices because of the impact of Apparel retailer’s TV advertisements. An advertisement is the paid type of unoriginal introduction of thoughts, products, and ventures by distinguished support. The primary goal of promoting is to advise, influence and remind the focused on shoppers with respect to the item. Consistently we go over an assortment of advertisements. When we read a daily paper or a magazine or tune in to the radio or stare at the television or stroll on a street or travel by a transport or a prepare or we see a film or go anyplace else, we run over a type of an advertisement. These advertisements fill in as the main thrust for our buy choices.The main objective of this paper is to study on the Impact of Television Advertising towards the Selection of Branded Women’s Apparel reference to a consumer at Tiruchirappalli City. A descriptive study was done on primary data collected from 125 respondents on basis of judgmental sampling. 125 respondents were given questionnaire and 110 were found to be fully usable for analysis. A questionnaire was used to collect primary data. Likert five-point scaling was given to customers for evaluating their impact of Demographical factors on Apparel retail store selection. IBM SPSS Statistic version 20.0 was used for this analysis and the following tools were administered 1) Reliability Test 2) Factor Analysis and 3) Multiple Regression 4) Chi-square goodness of fit test. The reliability test was made and the obtained coefficient alpha value (Cronbach’s alpha) was 0. 0.937, and hence the data had satisfactory reliability. Factor analysis and Multiple Regression was used to find the Impact of Television Advertising towards the Selection of Branded Women’s Apparel. In the Chi-square test, we are assessing how well the sample data fits the population proportions specified by the hypothesis

Isolation of Phytochemical and Evaluation of Antiasthmatic Potency of Ficus racemosa

The Present study reports important secondary metabolites present in Ficus racemosa The Ficus racemosa belong to the family Moraceae, it is popularly known as Glomerata, Cluster fig tree as well as ‘Udumbara’ in Marathi. Various plant parts such as bark, root, leaf, fruits are used as astringent, carminative, anti-dysentery, diabetes, leucoderma, antiasthmatic, hepatoprotective, antioxidant. The powdered Bark was subjected for extraction by using ethanol. These extract were evaluated for detection of various secondary metabolites, like Steroids, Glycosides, tannins, Terpenoids, Alkaloids, Flavonoids. This work evaluated the stem bark of this plant for its Phytochemical and Antiasthmatic activity. Keywords: Ficus racemosa, Steroids, Antiasthmatic, Moracea

Hydrolysis of proteinaceous tannery solid waste for the production of extracellular acidic protease by Selenomonas ruminantium

The objective of this study was to produce protease from Selenomonas ruminantium using animal fleshing (ANFL), an untanned tannery solid waste as the sole protein source. Optimization of the minimal medium composition for the production of protease was carried out by a statistical approach using response surface methodology (RSM) which includes the variables such as NH4Cl, K2HPO4, KH2PO4 and NaCl. The isolate was found to produce maximum protease at pH 6 and at a temperature of about 40°C. Protease was purified 56 fold with a total yield of 28.14%. The enzyme was found to be monomeric having a molecular weight around 53 kDa. The purified enzyme was stable at a pH of about 4 revealing its acid protease nature and was also found to be stable up to 40°C. The enzyme was activated by divalent cations like Ca2+ and Mg2+ and inhibited by dithiothreitol (DTT), where the latter suggested its cysteine protease nature. The enzyme had good stability in the presence of non-ionic surfactants like tween 20, tween 40, tween 80 and triton X100 and also in the presence of solvents like methanol, ethanol and isopropanol. These characteristics reveal the potential of the enzyme for different industrial applications.Keywords: Acid protease, animal fleshing, optimization, response surface methodology (RSM), Selenomonas ruminantiu

Jamming Attack Detection and Evaluating Using Wireless Application

When data is transferred from one host to another host,attacker may try to attack the packet or data which is in transit.Inorder to avoid such kind of attack in time critical wireless application and delivery message securely in wireless application. In this paper, we aim at modeling and detecting jamming attacks against time-critical wireless networks.To measure network performance ,packet loss and throughput metrics are used . To quantify the performance of time-critical applications,message invalidation ratio metric are used. This approach is inspired by the similarity between the behavior of a jammer who attempts to disrupt the delivery of a message and the behavior of a gambler who intends to win a gambling game. By gambling-based modeling and real-time modules, we can successful delivery time-critical message under a variety of jamming attacks. DOI: 10.17762/ijritcc2321-8169.15038