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Microcirculatory blood flow: Functional implications of a complex fluid
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, Aristotle University of Thessaloniki, University of Thessaly, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute
The balanced tensor product of module categories
The balanced tensor product M (x)_A N of two modules over an algebra A is the vector space corepresenting A-balanced bilinear maps out of the product M x N. The balanced tensor product M [x]_C N of two module categories over a monoidal linear category C is the linear category corepresenting C-balanced right-exact bilinear functors out of the product category M x N. We show that the balanced tensor product can be realized as a category of bimodule objects in C, provided the monoidal linear category is finite and rigid
Decomposability of soil organic matter over time: the Soil Incubation Database (SIDb, version 1.0) and guidance for incubation procedures
Using respiration quotients to track changing sources of soil respiration seasonally and with experimental warming
A simplified particulate model for coarse-grained hemodynamics simulations
Human blood flow is a multi-scale problem: in first approximation, blood is a
dense suspension of plasma and deformable red cells. Physiological vessel
diameters range from about one to thousands of cell radii. Current
computational models either involve a homogeneous fluid and cannot track
particulate effects or describe a relatively small number of cells with high
resolution, but are incapable to reach relevant time and length scales. Our
approach is to simplify much further than existing particulate models. We
combine well established methods from other areas of physics in order to find
the essential ingredients for a minimalist description that still recovers
hemorheology. These ingredients are a lattice Boltzmann method describing rigid
particle suspensions to account for hydrodynamic long range interactions
and---in order to describe the more complex short-range behavior of
cells---anisotropic model potentials known from molecular dynamics simulations.
Paying detailedness, we achieve an efficient and scalable implementation which
is crucial for our ultimate goal: establishing a link between the collective
behavior of millions of cells and the macroscopic properties of blood in
realistic flow situations. In this paper we present our model and demonstrate
its applicability to conditions typical for the microvasculature.Comment: 12 pages, 11 figure
BMW – Mastering the Crises with “New Efficiency?”
Purpose Make a contribution on company business models and typical reactions to economic crises. Design/methodology/approach Media-analysis-based case study. Findings Crisis is handled through drawing on a strategy deriving from the typical features of the company; through the crisis these features are even intensified. Research limitations/implications Multinational companies are complex and only transparent to a small degree; the empirical data therefore rests on a database with articles. Social implications Social implications can be seen at the BMW as a functioning example for social partnership as a form of economic embeddedness at the societal level
The Migration of Elites in a Borderless World: Citizenship as an Incentive for Professionals and Managers?
Der Artikel geht der Frage nach, inwiefern die geöffneten Türen für die Immigration Hochqualifizierter in den OECD-Ländern tatsächlich zu einer verstärkten Migrationsbewegung führen. Die Analyse von Daten zu Eliten- und Hochqualifiziertenmigration in Ostasien, Europa und den USA führt zu dem Ergebnis, dass diese dem Muster einer „brain circulation“ folgt und die Staatsbürgerrechte dabei keine entscheidende Rolle spielen
The endothelial glycocalyx prefers albumin for evoking shear stress-induced, nitric oxide-mediated coronary dilatation
Background: Shear stress induces coronary dilatation via production of nitric oxide ( NO). This should involve the endothelial glycocalyx ( EG). A greater effect was expected of albumin versus hydroxyethyl starch ( HES) perfusion, because albumin seals coronary leaks more effectively than HES in an EG-dependent way. Methods: Isolated hearts ( guinea pigs) were perfused at constant pressure with Krebs-Henseleit buffer augmented with 1/3 volume 5% human albumin or 6% HES ( 200/0.5 or 450/0.7). Coronary flow was also determined after EG digestion ( heparinase) and with nitro-L-arginine ( NO-L-Ag). Results: Coronary flow ( 9.50 +/- 1.09, 5.10 +/- 0.49, 4.87 +/- 1.19 and 4.15 +/- 0.09 ml/ min/ g for `albumin', `HES 200', `HES 450' and `control', respectively, n = 5-6) did not correlate with perfusate viscosity ( 0.83, 1.02, 1.24 and 0.77 cP, respectively). NO-L-Ag and heparinase diminished dilatation by albumin, but not additively. Alone NO-L-Ag suppressed coronary flow during infusion of HES 450. Electron microscopy revealed a coronary EG of 300 nm, reduced to 20 nm after heparinase. Cultured endothelial cells possessed an EG of 20 nm to begin with. Conclusions: Albumin induces greater endothelial shear stress than HES, despite lower viscosity, provided the EG contains negative groups. HES 450 causes some NO-mediated dilatation via even a rudimentary EG. Cultured endothelial cells express only a rudimentary glycocalyx, limiting their usefulness as a model system. Copyright (c) 2007 S. Karger AG, Basel
Semiflexible polymer conformation, distribution and migration in microcapillary flows
The flow behavior of a semiflexible polymer in microchannels is studied using
Multiparticle Collision Dynamics (MPC), a particle-based hydrodynamic
simulation technique. Conformations, distributions, and radial cross-streamline
migration are investigated for various bending rigidities, with persistence
lengths Lp in the range 0.5 < Lp/Lr < 30. The flow behavior is governed by the
competition between a hydrodynamic lift force and steric wall-repulsion, which
lead to migration away from the wall, and a locally varying flow-induced
orientation, which drives polymer away from the channel center and towards the
wall. The different dependencies of these effects on the polymer bending
rigidity and the flow velocity results in a complex dynamical behavior.
However, a generic effect is the appearance of a maximum in the monomer and the
center-of-mass distributions, which occurs in the channel center for small flow
velocities, but moves off-center at higher velocities.Comment: in press at J. Phys. Condens. Matte
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