249 research outputs found
Computation of Gait Parameters in Post Stroke and Parkinson’s Disease: A Comparative Study Using RGB‐D Sensors and Optoelectronic Systems
Usability of the REHOME Solution for the Telerehabilitation in Neurological Diseases: Preliminary Results on Motor and Cognitive Platforms
Performance at the clock drawing test of individuals affected by Parkinson’s disease and healthy subjects: a retrospective study
A Compartmental Model for the Iron Trafficking Across the Blood-Brain Barriers in Neurodegenerative Diseases
Are the neurophysiological techniques useful for the diagnosis of diaphragmatic impairment in multiple sclerosis (MS)?
Effects of Circadian Phase Tailored Light Therapy on Sleep, Mood, and Cognition in Alzheimer’s Disease: Preliminary Findings in a Pivotal Study
In polycistronic Qβ RNA, single-strandedness at one ribosome binding site directly affects translational initiations at a distal upstream cistron
In Qβ RNA, sequestering the coat gene ribosome binding site in a putatively strong hairpin stem structure eliminated synthesis of coat protein and activated protein synthesis from the much weaker maturation gene initiation site, located 1300 nucleotides upstream. As the stability of a hairpin stem comprising the coat gene Shine–Dalgarno site was incrementally increased, there was a corresponding increase in translation of maturation protein. The effect of the downstream coat gene ribosome binding sequence on maturation gene expression appeared to have occurred only in cis and did not require an AUG start codon or initiation of coat protein synthesis. In all cases, no structural reorganization was predicted to occur within Qβ RNA. Our results suggest that protein synthesis from a relatively weak translational initiation site is greatly influenced by the presence or absence of a stronger ribosome binding site located elsewhere on the same RNA molecule. The data are consistent with a mechanism in which multiple ribosome binding sites compete in cis for translational initiations as a means of regulating protein synthesis on a polycistronic messenger RNA
Estudio estadístico del estado de conservación de pavimentos de hormigón del sector SE de Bahía Blanca (Buenos Aires)
En el presente trabajo se relevaron pavimentos de hormigón de la ciudad de Bahía Blanca con el propósito de determinar el estado de conservación y las causas de deterioro. Se presentan los resultados de 43 barrios del sector SE de la ciudad, que abarca una superficie de 13,4 km2. Se analizó el estado de las losas considerando las que necesitan reemplazo debido al avanzado estado de deterioro y el tipo de agregado que constituye el hormigón. Se determinó densidad, absorción y porosidad y se realizó un estudio petrográfico de los agregados y del estado del mortero, utilizando estereomicroscopio y microscopio óptico. Se realizó un estudio estadístico sobre un total de 32703 losas relevadas y se concluyó que el 40% presenta deterioro y de éstas, el 18% necesita reemplazo total. Las principales causas de falla están asociadas a defectos constructivos en la preparación de bases y a la falta de mantenimiento de juntas
Transoesophageal echocardiography in patients without arterial and major cardiac sources of embolism: difference between stroke subtypes.
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