267 research outputs found
ANALYTICAL METHODS FOR THE DETERMINATION OF AMINOGLYCOSIDES ANTIBIOTICS BY CHROMATROGRAPHIC TECHNIQUE
Aminoglycosides antibiotics are considered to be the antimicrobial agents used frequently in the treatment of human diseases caused by a bacterial infection. Most of the aminoglycosides antibiotics are highly polar in nature and they are lacking the UV absorbing chromophore in the molecules. The present articles accentuate the analytical method associated with the analysis of aminoglycosides molecules. Various chromatographic techniques like liquid chromatography, gas chromatography; mass spectrometry were used for the detection of aminoglycosides antibiotics. However, due to its limitation in the ultraviolet-visible spectrophotometry (UV/Vis) technique, different types of detection techniques like corona-charged aerosol detector (CAD), electrochemical detector (ECD) were used as a most powerful and versatile technique for the demonstration of these molecules in the analytical field. Analytical methods help to ensure the quality of the drug products. This review paper is devoted to providing an overview of the key performance technique used for the application and detection of these aminoglycosides molecules
Effect of protein deficiency on absorption, transport and distribution of α-tocopherol in the rat
The absorption, transport and distribution of α-[3H]tocopherol were greatly decreased in protein deficiency. This was reflected in the subcellular distribution of α-[3H]tocopherol in livers of protein-deficient rats. The ratio, bound: free for α-[3H]tocopherol, also decreased in both serum and liver cytosol. After protein refeeding, absorption, transport and distribution patterns of α-[3H]tocopherol for the protein-deficient rats were restored to patterns similar to those of control animals
Sediment and water characteristics of selected prawn farming sites at Cochin during premonsoon months
This paper deals with the studies on sediment and water characteristics of selected shrimp
farming ponds located at Puthuvyppu and Valappu villages of Vypeen in the vicinity of
Cochin carried out during premonsoon period (March-May 2001). Areawise distribution of
sediment and water characteristics revealed that smaller and medium sized ponds were
relatively more fertile than the larger sized ponds. Overall mean values of nutrients in sediment
and water indicated that ponds at Puthuvyppu village (with high tidal influence) were relatively
more fertile than those ponds at Valappu. TSS and primary productivity values also showed
the same trend. Highly significant positive correlation was observed between clay and silt,
organic carbon and available potassium, nitrite-N in sediment and water, salinity and TSS and
water pH and dissolved oxygen
Is the Scyphozoan jellyfish Lychnorhiza malayensis symbiotically associated with the crucifix crab Charybdis feriatus?
Scyphozoan jellyfish (Medusae), the
gelatinous invertebrate group, plays a
vital role in the global oceanic and
coastal ecosystems. By virtue of their
floating nature, and horizontal and vertical
spread in the water column, they are
known to have varied associations with
other invertebrates and teleosts, which
make them an integral part of the marine
ecosystem
Climate change impacts on coastal lakes: an evaluation of the impact on Vembanad, Chilka and Pulicat lakes and their resources
Bivalves play key role in ecosystem stabilisation
due to inherent filter feeding capability and clams
are important components of soft bottom benthic
communities. In the Tuticorin Bay, mass mortality
of fishes and shellfishes was observed in Februay
2008. The probable cause for the large scale mortality
has been indicated as increased levels of ammonia
(Asha et al., 2009). A rapid survey was conducted in
the bay to assess the impact on the bivalve fauna
Techniques of deep learning and image processing in plant leaf disease detection: a review
Computer vision techniques are an emerging trend today. Digital image processing is gaining popularity because of the significant upsurge in the usage of digital images over the internet. Digital image processing is a practice that can help in designing sophisticated high-end machines, which can hold the ophthalmic functionality of the human eye. In agriculture, leaf examination is important for disease identification and fair warning for any deficiency within the plant. Many prominent plant species are facing extinction because of a lack of knowledge. A proper realization of computer vision techniques aid in extracting a significant amount of information from leaf image. This necessitates the requirement of an automatic leaf disease detection method to diagnose disease occurrences and severity, for timely crop management, by spraying pesticides. This study focuses on techniques of digital image processing and machine learning rendered in plant leaf disease detection, which has great potential in precision agriculture. To support this study, techniques exercised by various researchers in recent years are tabulated
Habitat destruction: a case study on the evaluation of litter in the marine zone of north Vembanad Lake, Kerala
Bivalves play key role in ecosystem stabilisation
due to inherent filter feeding capability and clams
are important components of soft bottom benthic
communities. In the Tuticorin Bay, mass mortality
of fishes and shellfishes was observed in Februay
2008. The probable cause for the large scale mortality
has been indicated as increased levels of ammonia
(Asha et al., 2009). A rapid survey was conducted in
the bay to assess the impact on the bivalve fauna
Bioavailability of rifampicin following concomitant administration of ethambutol or isoniazid or pyrazinamide or a combination of the three drugs
Background & Objectives: Poor bioavailability of rifampicin (R) in combination with other
anti-tuberculosis drugs such as isoniazid (H), pyrazinamide (Z), and ethambutol (E) is a subject of
much concern for the last few decades. This could be due to an interaction between R and other drugs.
An investigation was therefore undertaken to examine the bioavailability of R in the presence of H, Z
and E or a combination of the three drugs.
Methods: The study included eight healthy volunteers, each being investigated on four occasions at
weekly intervals once with R alone and with three of the four combinations on the three remaining
occasions. A partially balanced incomplete block design was employed and the allocation of R or the
drug combinations was random. Plasma concentrations of R at intervals upto 12 h were determined by
microbiological assay using Staphylococcus aureus as the test organism. The proportion (%) dose of R
as R plus desacetyl R (DR) in urine excreted over the periods 0-8 and 8-12 h was also determined.
Bioavailability was expressed as an index (BI) of area under time concentration curve (AUC) calculated
from the plasma concentrations or proportion of dose of R excreted as R plus DR in urine with the
combinations to that with R alone.
Results: The bioavailability indices based on AUC were 0.96 with RE, 0.76 with RH, 1.08 with RZ and
0.65 with REHZ. The indices based on urine estimations (0-8 h) were similar, the values being 0.94,
0.84, 0.94 and 0.75, respectively. A second investigation revealed that the decrease of bioavailability of
R with H was not due to the excipients present in H tablets.
Interpretation & conclusion: Isoniazid alone or in combination with E and Z reduces the bioavailability
of R. Urinary excretion data offer a simple and non invasive method for the assessment of bioavailability
of R
Implementing Mathematical Morphology Techniques to Detect Cracks in Underground Pipeline Images Automatically
An oil pipe buried under needs to be checked for their current quality before oil transportation takes place through it. The method involved for all these days were manual usin
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