15 research outputs found
DroidAutoML: A Microservice Architecture to Automate the Evaluation of Android Machine Learning Detection Systems
Part 4: Machine Learning for SystemsInternational audienceThe mobile ecosystem is witnessing an unprecedented increase in the number of malware in the wild. To fight this threat, actors from both research and industry are constantly innovating to bring concrete solutions to improve security and malware protection. Traditional solutions such as signature-based anti viruses have shown their limits in front of massive proliferation of new malware, which are most often only variants specifically designed to bypass signature-based detection. Accordingly, it paves the way to the emergence of new approaches based on Machine Learning (ML) technics to boost the detection of unknown malware variants. Unfortunately, these solutions are most often underexploited due to the time and resource costs required to adequately fine tune machine learning algorithms. In reality, in the Android community, state-of-the-art studies do not focus on model training, and most often go through an empirical study with a manual process to choose the learning strategy, and/or use default values as parameters to configure ML algorithms. However, in the ML domain, it is well known admitted that to solve efficiently a ML problem, the tunability of hyper-parameters is of the utmost importance. Nevertheless, as soon as the targeted ML problem involves a massive amount of data, there is a strong tension between feasibility of exploring all combinations and accuracy. This tension imposes to automate the search for optimal hyper-parameters applied to ML algorithms, that is not anymore possible to achieve manually. To this end, we propose a generic and scalable solution to automatically both configure and evaluate ML algorithms to efficiently detect Android malware detection systems. Our approach is based on devOps principles and a microservice architecture deployed over a set of nodes to scale and exhaustively test a large number of ML algorithms and hyper-parameters combinations. With our approach, we are able to systematically find the best fit to increase up to 11% the accuracy of two state-of-the-art Android malware detection systems
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Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.
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Subcortical brain volume abnormalities in 2028 individuals with schizophrenia and 2540 healthy controls via the ENIGMA consortium.
The profile of brain structural abnormalities in schizophrenia is still not fully understood, despite decades of research using brain scans. To validate a prospective meta-analysis approach to analyzing multicenter neuroimaging data, we analyzed brain MRI scans from 2028 schizophrenia patients and 2540 healthy controls, assessed with standardized methods at 15 centers worldwide. We identified subcortical brain volumes that differentiated patients from controls, and ranked them according to their effect sizes. Compared with healthy controls, patients with schizophrenia had smaller hippocampus (Cohen's d=-0.46), amygdala (d=-0.31), thalamus (d=-0.31), accumbens (d=-0.25) and intracranial volumes (d=-0.12), as well as larger pallidum (d=0.21) and lateral ventricle volumes (d=0.37). Putamen and pallidum volume augmentations were positively associated with duration of illness and hippocampal deficits scaled with the proportion of unmedicated patients. Worldwide cooperative analyses of brain imaging data support a profile of subcortical abnormalities in schizophrenia, which is consistent with that based on traditional meta-analytic approaches. This first ENIGMA Schizophrenia Working Group study validates that collaborative data analyses can readily be used across brain phenotypes and disorders and encourages analysis and data sharing efforts to further our understanding of severe mental illness