Spores, Viable Organisms, and other Tribulations in Planetary Protection Requirements for Mars and Europa

This presentation is being presented to the 15th Annual International Planetary Probe Workshop. Some of the topics of discussion will include a Brief History of Planetary Protection, U.S. Signatory to United Nations Outer Space Treaty (OST), COSPAR Panel on Planetary Protection, Validating Science and Protecting Earth's Biosphere, Viking-Level Bioload Is Still the Gold Standard, Provisions for Robotic Extraterrestrial Missions, Temporary Assay Labs, A Viable Organism Is One That Can Replicate, Non-Nominal Landing in a Special Region, Mars 2020 Category IVb, Europa and Enceladus

Bifurcated polarization rotation in bismuth-based piezoelectrics

ABO3 perovskite-type solid solutions display a large variety of structural and physical properties, which can be tuned by chemical composition or external parameters such as temperature, pressure, strain, electric, or magnetic fields. Some solid solutions show remarkably enhanced physical properties including colossal magnetoresistance or giant piezoelectricity. It has been recognized that structural distortions, competing on the local level, are key to understanding and tuning these remarkable properties, yet, it remains a challenge to experimentally observe such local structural details. Here, from neutron pair-distribution analysis, a temperature-dependent 3D atomic-level model of the lead-free piezoelectric perovskite Na0.5Bi0.5TiO3 (NBT) is reported. The statistical analysis of this model shows how local distortions compete, how this competition develops with temperature, and, in particular, how different polar displacements of Bi3+ cations coexist as a bifurcated polarization, highlighting the interest of Bi-based materials in the search for new lead-free piezoelectrics

Describing transverse dynamics and space-time evolution at RHIC in a hydrodynamic model with statistical hadronization

A hydrodynamic model coupled to the statistical hadronization code Therminator is used to study a set of observables in the soft sector at RHIC. A satisfactory description of the pT-spectra and elliptic flow is obtained, similarly to other hydrodynamic models. With the Gaussian initial conditions the transverse femtoscopic radii are also reproduced, providing a possible solution of the RHIC HBT puzzle.Comment: to appear in the conference proceedings for Quark Matter 2009, March 30 - April 4, Knoxville, Tennesse

Designing Spacecraft Power Systems to Solve Planetary Protection Challenges

This presentation of spacecraft power systems to solve planetary protection, includes topics such as Planetary Protection requirements, Enduring Authority of the Outer Space Treaty, Relationship to COSPAR, Planetary Protection Mission Categories (NASA/ESA/COSPAR Policy)

Introduction to geochemistry of metalliferous black shales

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/29848/1/0000195.pd

Association between Ophthalmic Timolol and Hospitalisation for Bradycardia

Introduction. Ophthalmic timolol, a topical nonselective beta-blocker, has the potential to be absorbed systemically which may cause adverse cardiovascular effects. This study was conducted to determine whether initiation of ophthalmic timolol was associated with an increased risk of hospitalisation for bradycardia. Materials and Methods. A self-controlled case-series study was undertaken in patients who were hospitalised for bradycardia and were exposed to timolol. Person-time after timolol initiation was partitioned into risk periods: 1–30 days, 31–180 days, and >180 days. A 30-day risk period prior to initiating timolol was also included. All remaining time was considered unexposed. Results. There were 6,373 patients with at least one hospitalisation for bradycardia during the study period; 267 were exposed to timolol. Risk of bradycardia was significantly increased in the 31–180 days after timolol initiation (incidence rate ratio (IRR) = 1.93; 95% confidence interval (CI) 1.00–1.87). No increased risk was observed in the first 30 days or beyond 180 days of continuous exposure (IRR = 1.40; 95% CI 0.87–2.26 and IRR = 1.21; 95% CI 0.64–2.31, resp.). Conclusion. Bradycardia is a potential adverse event following timolol initiation. Practitioners should consider patient history before choosing a glaucoma regime and closely monitor patients after treatment initiation with topical nonselective beta-blocker eye drops

Transport model analysis of the transverse momentum and rapidity dependence of pion interferometry at SPS energies

Based on the UrQMD transport model, the transverse momentum and the rapidity dependence of the Hanbury-Brown-Twiss (HBT) radii $R_L$, $R_O$, $R_S$ as well as the cross term $R_{OL}$ at SPS energies are investigated and compared with the experimental NA49 and CERES data. The rapidity dependence of the $R_L$, $R_O$, $R_S$ is weak while the $R_{OL}$ is significantly increased at large rapidities and small transverse momenta. The HBT "life-time" issue (the phenomenon that the calculated $\sqrt{R_O^{2}-R_S^{2}}$ value is larger than the correspondingly extracted experimental data) is also present at SPS energies.Comment: 17 pages, 11 figure

Imaging Sources with Fast and Slow Emission Components

We investigate two-proton correlation functions for reactions in which fast dynamical and slow evaporative proton emission are both present. In such cases, the width of the correlation peak provides the most reliable information about the source size of the fast dynamical component. The maximum of the correlation function is sensitive to the relative yields from the slow and fast emission components. Numerically inverting the correlation function allows one to accurately disentangle fast dynamical from slow evaporative emission and extract details of the shape of the two-proton source.Comment: 13 pages, 4 figure

System-size dependence of the pion freeze-out volume as a potential signature for the phase transition to a Quark Gluon Plasma

Hanburry-Brown-Twiss (HBT) correlation functions and radii of negatively charged pions from C+C, Si+Si, Cu+Cu, and In+In at lower RHIC/SPS energies are calculated with the UrQMD transport model and the CRAB analyzing program. We find a minimum in the excitation function of the pion freeze-out volume at low transverse momenta and around $E_{lab}\sim 20-30A$GeV which can be related to the transition from hadronic to string matter (which might be interpreted as a pre-cursor of the QGP). The existence of the minimum is explained by the competition of two mechanisms of the particle production, resonance decays and string formation/fragmentation.Comment: 12 pages, 4 fig

Recommendations for Clinical CYP2C19 Genotyping Allele Selection: A Report of the Association for Molecular Pathology

This document was developed by the Pharmacogenetics (PGx) Working Group of the Association for Molecular Pathology Clinical Practice Committee, whose aim is to recommend variants for inclusion in clinical pharmacogenetic testing panels. The goals of the Association for Molecular Pathology PGx Working Group are to define the key attributes of PGx alleles recommended for clinical testing and to define a minimum set of variants that should be included in clinical PGx genotyping assays. These recommendations include a minimum panel of variant alleles (tier 1) and an extended panel of variant alleles (tier 2) that will aid clinical laboratories when designing PGx assays. The Working Group considered variant allele frequencies in different populations and ethnicities, the availability of reference materials, and other technical considerations for PGx testing when developing these recommendations. These CYP2C19 genotyping recommendations are the first of a series of recommendations for PGx testing. These recommendations are not to be interpreted as restrictive, but they are meant to provide a helpful guide