24 research outputs found

    A Critical Evaluation on Akala Palitam

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    Hair color reflects the health of an individual and the discolored hair indicates the pathological state. Palitam is a physiological process when it occurring in old age. Whereas Akala Palitam (premature graying) is a pathological condition manifests in early stages of life. It is characterized byVivarna Kesha (discolored hair) along with altered hair texture and the predominant Dosha attributes Vivarnata to Kesha. Hair color is determined by a pigment called melanin (relative proportions of eumelanins and phaeomelanins) in hair follicles. Diffuse loss of hair melanin during early stages of liferesults in premature graying. In Ayurveda, Bhrajaka Pitta, one among the five types of Pitta located in skin is responsible for the attribution of hair colour. Thus it performs the function similar to melanin pigment in hair follicles. When there is Pitta dosha Vridhi in Rasadhatu along with vitiation of other two Doshas it leads to manifestation of Vivarna Kesha with altered hair texture thus results in Akala Palitam. It is a type of Raspradoshajavikara in which the signs and symptoms varies based on the predominant Dosha. Treatment option for Akala Palitam is also specific based on predominant Dosha. So a critical evaluation on Akala Palitam is essential to understand the etio-pathogenesis of the disease for its better management

    A Clinical Approach to Hirsutism

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    Hirsutism is a condition of hyper androgenism, which is defined as androgen- dependent excessive male- pattern hair growth, affects approximately 10% of women with or without complex underlying pathology. It is a physiological phenomenon if it occurs with a familial history and is considered as a serious condition if it is due to various metabolic and genetic causes along with androgen secreting tumors. Hence an apt treatment is only possible after a proper diagnosis. In our classics, there is no direct term for hirsutism is mentioned. But we can decipher relative aspects from multiple references regarding hair and hair growth. Even though, based on the Dushya involvement it can be considered as a condition of Kapha Pradhana Tridosha Kopa. Hence based on a proper diagnosis through an apt diagnostic technique Abhyantara (internal) as well as Bahya (external) Chikitsa (treatment) like depilation techniques, use of Lepa (topical medicaments), oil etc

    Iodine-catalyzed stereoselective synthesis of allylglycosides, glycosyl cyanides and glycosyl azides

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    Iodine efficiently catalyzes the glycosidation of glycals with allyltrimethylsilane, trimethylsilyl cyanide and trimethylsilyl azide in dichloromethane at ambient temperature to afford the corresponding 2,3-unsaturated allyl glycosides, glycosyl cyanides and glycosyl azides in excellent yields with high α-selectivity
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