Scrotal Lipoma - A Case Study

Lipoma is one of the commonest benign mesenchymal tumor. It occurs with an incidence of 1% of the population. It is composed of fat cells of adult type. It may occur any where in the body, hence called Universal tumor or ubiquitous tumor. But lipomas with in the scrotum are rare and are included under para testicular or extra testicular tumors. To date, definite etiology of lipoma remains uncertain. One theory suggests cytokine release may trigger pre-adipocyte differentiation and maturation. Here we report a case of scrotal lipoma presented as a painless swelling in the scrotum

COMPARATIVE PHARMACOGNOSTIC STUDIES OF ROOTS OF ASHWAGANDHA (WILD, NAGORI AND POSHITHA VAR)

Background: Ashwagandha is a very well-known herb in Ayurveda. It is widely used in pharmaceutical, cosmetic, agricultural, food industries, and is a constituent of over 200 Ayurvedic formulations. The annual demand of Ashwagandha is 7000 tons but its actual availability is just 1500 tons, this demand is not met by using the wildly grown Ashwagandha. To meet this demand, it has been brought under cultivation many centuries ago, in India. Numerous cultivated varieties of Ashwagandha are developed for high yield and better quality roots. Amongst them, Nagori Ashwagandha is a popular variety, cultivated for its demand. Poshitha Ashwagandha is a high yielding and improved variety released by CSIR-CIMAPS. The current study aims at comparing the roots of wildly grown Ashwagandha, Nagori Ashwagandha and Poshitha Ashwagandha, pharmacognostically. Methodology: The study deals with macroscopic parameters, microscopic study of transverse sections physicochemical, phytochemical analysis and powder microscopy of roots of the three varieties of Ashwagandha. Results: Significant macroscopic differences were noted between the wild and the two cultivated varieties of Ashwagandha roots, there was no much variation in the physico-chemical and phyto-chemical parameters amongst the three, also there was no much difference found between the two cultivated varieties- morphologically and phyto-chemically

Design and implementation of DA FIR filter for bio-inspired computing architecture

This paper elucidates the system construct of DA-FIR filter optimized for design of distributed arithmetic (DA) finite impulse response (FIR) filter and is based on architecture with tightly coupled co-processor based data processing units. With a series of look-up-table (LUT) accesses in order to emulate multiply and accumulate operations the constructed DA based FIR filter is implemented on FPGA. The very high speed integrated circuit hardware description language (VHDL) is used implement the proposed filter and the design is verified using simulation. This paper discusses two optimization algorithms and resulting optimizations are incorporated into LUT layer and architecture extractions. The proposed method offers an optimized design in the form of offers average miminimizations of the number of LUT, reduction in populated slices and gate minimization for DA-finite impulse response filter. This research paves a direction towards development of bio inspired computing architectures developed without logically intensive operations, obtaining the desired specifications with respect to performance, timing, and reliability

Multiple median nerve abscesses: A rare presentation of leprosy

A 25 year old male presented with swellings around the left elbow and forearm since 2 years. Examination showed 4 swellings along the course of median nerve over the left arm, elbow and forearm. They were circumscribed, soft to firm nodules with tenderness. There were no cutaneous lesions suggesting of leprosy. Histopathological examination of a biopsy from a swelling showed granulomas in the epineurium suggesting the diagnosis of leprosy neuritis. With these clinico-pathological features diagnosis of median nerve abscesses was confirmed. The patient was treated with multi drug therapy for leprosy and oral steroids

An Altered Pulmonary Function – A Cause or Consequence of Gastro Esophageal Reflux Disease (GERD)

Objective: To evaluate the pulmonary function in Gastroesophageal reflux disease (GERD) patients without respiratory symptoms. Background: GERD is reported to adversely impact the pulmonary functions. GERD is associated with symptomatic asthma and chronic cough. Pulmonary functions are studied in symptomatic asthma patients with GERD. Treatment of GERD improves the respiratory symptoms and decreases the medication needed for the management of asthma. This study was undertaken to evaluate the pulmonary functions in GERD patients without respiratory symptoms. Methods: A cross sectional study was conducted in clinically diagnosed GERD cases (18 males and 15 females), confirmed by endoscopic examination without respiratory symptoms. Age, gender and anthropometrically matched healthy subjects served as controls. Pulmonary functions (FVC, FEV1, FEV1/FVC ratio and PEFR) were recorded using a computerized spirometer (Spirobank G) in sitting position. Percentage of predicted values was expressed as mean ± SD and was used for comparison. Results: There was a statistically significant reduction in FVC, FEV1 and PEFR in GERD patients without respiratory symptoms compared to controls (p < 0.05). Conclusion: It can be concluded that subjects suffering from GERD without respiratory symptoms also have an altered pulmonary function showing predominantly obstructive type with mild to moderate restrictive airway changes

Super capacitor, electrochemical measurement and sun light driven photocatalytic applications of CuFe2O4 NPs synthesized from bio-resource extract

The CuFe2O4 nanoparticle has been successfully synthesized from bio-mediated (Aloe-Vera) combustion process. The structural characterization of synthesized nanoparticle was achieved by spectral-characterizations viz; XRD, SEM, FT-IR and optical examinations. The XRD studies displays a spinel cubic phase development of nanoparticle and its average-particle size (19.3 ​nm). Low band gap energy of synthesized nanoparticle has been recorded to be 2.84 ​eV using UV–Visible absorption spectroscopy, which impacts to higher photodegradation efficiency. The potential photocatalytic activity of synthesized nanoparticle was examined using Malachite Green (MG) organic dye as a model, which is performed under specific quantities of stock solution (60 ​ppm) and obtained nanoparticle (50 ​mg). The photodegradation efficiency of synthesized material was evaluated for MG dye degradation achieved with 87.5% at 140 ​min under Sun-light. The excellent oxidation-reduction peak potentials were observed for synthesized spinel ferrite nanoparticle modified with carbon paste investigated by electrochemical analysis using 0.1 ​M KCl in the different scan rates 0.01–0.05 ​V/s. The charge-discharge studies of CuFe2O4-graphite electrode at current density (0.4 A/g) was discussed which is well correspondence to pseudo-capacitive behaviour. The synthesized NPs through bio-resources extract has become a potential new insight into multiple practical applications