C6: Knowledge, attitude, and practice of senior dental students toward management of complications in exodontia

Introduction: Dental graduates have a professional responsibility of being competent in managing the complications in exodontia, a very commonly performed procedure. Aim: The aim of this paper was to assess the knowledge, attitude, and practice of senior dental students toward the management of complications in exodontia. Materials and Methods: Four hundred dental students participated in the study voluntarily. Verbal consent was obtained after elaborating the purpose of the study. A short validated questionnaire consisting of 12 close-ended multiple choice questions was distributed to all the students. The questionnaires were collected back and results from fully filled questionnaires were tabulated in Microsoft Excel 2007. Results: Nearly 93.4% of the students perform extractions in their practice on a routine basis. Among those 32.5% of the students have encountered complications, out of which only 20% of the students are confident in managing them. The remaining 64.8% of students who have not encountered complications are not confident in managing the same. Conclusion: This study revealed the need for increase in cases which will in turn help the students to transfer their theoretical knowledge into professional skills

BMI and all cause mortality: systematic review and non-linear dose-response meta-analysis of 230 cohort studies with 3.74 million deaths among 30.3 million participants

 To conduct a systematic review and meta-analysis of cohort studies of body mass index (BMI) and the risk of all cause mortality, and to clarify the shape and the nadir of the dose-response curve, and the influence on the results of confounding from smoking, weight loss associated with disease, and preclinical disease. PubMed and Embase databases searched up to 23 September 2015. Cohort studies that reported adjusted risk estimates for at least three categories of BMI in relation to all cause mortality. Summary relative risks were calculated with random effects models. Non-linear associations were explored with fractional polynomial models. 230 cohort studies (207 publications) were included. The analysis of never smokers included 53 cohort studies (44 risk estimates) with >738 144 deaths and >9 976 077 participants. The analysis of all participants included 228 cohort studies (198 risk estimates) with >3 744 722 deaths among 30 233 329 participants. The summary relative risk for a 5 unit increment in BMI was 1.18 (95% confidence interval 1.15 to 1.21; I(2)=95%, n=44) among never smokers, 1.21 (1.18 to 1.25; I(2)=93%, n=25) among healthy never smokers, 1.27 (1.21 to 1.33; I(2)=89%, n=11) among healthy never smokers with exclusion of early follow-up, and 1.05 (1.04 to 1.07; I(2)=97%, n=198) among all participants. There was a J shaped dose-response relation in never smokers (Pnon-linearity <0.001), and the lowest risk was observed at BMI 23-24 in never smokers, 22-23 in healthy never smokers, and 20-22 in studies of never smokers with ≥20 years follow-up. In contrast there was a U shaped association between BMI and mortality in analyses with a greater potential for bias including all participants, current, former, or ever smokers, and in studies with a short duration of follow-up (<5 years or <10 years), or with moderate study quality scores. Overweight and obesity is associated with increased risk of all cause mortality and the nadir of the curve was observed at BMI 23-24 among never smokers, 22-23 among healthy never smokers, and 20-22 with longer durations of follow-up. The increased risk of mortality observed in underweight people could at least partly be caused by residual confounding from prediagnostic disease. Lack of exclusion of ever smokers, people with prevalent and preclinical disease, and early follow-up could bias the results towards a more U shaped association

A Monopole-Antimonopole Solution of the SU(2) Yang-Mills-Higgs Model

As shown by Taubes, in the Bogomol'nyi-Prasad-Sommerfield limit the SU(2) Yang-Mills-Higgs model possesses smooth finite energy solutions, which do not satisfy the first order Bogomol'nyi equations. We construct numerically such a non-Bogomol'nyi solution, corresponding to a monopole-antimonopole pair, and extend the construction to finite Higgs potential.Comment: 11 pages, including 4 eps figures, LaTex format using RevTe

Effect of Lutein in the expression of PPARα and LDLR in hypercholesterolemic male Wistar Rats

Background: Hyperlipidemia is a well known risk factor for cardiovascular disease, especially atherosclerotic coronary artery disease. Peroxisome proliferator activated receptor α (PPARα), a member of this nuclear receptor family, has emerged as an important player in this scenario, with evidence supporting a central co-ordinated role in the regulation of fatty acid oxidation, lipid and lipoprotein metabolism and inflammatory and vascular responses, all of which would be predicted to reduce atherosclerotic risk. The low-density lipoprotein (LDL) receptor (LDLR) is the primary pathway for removal of cholesterol from the circulation, and its activity is meticulously governed by intracellular cholesterol levels. Hence in this study we investigated the effect of Lutein on PPARα and LDLR expression in liver of wistar rats.Methods: Male Wistar rats were divided into 6 groups of 6 each. Group I served as control. Group II III, IV, V and VI rats were received high cholesterol diet. Group III was treated with Atorvastatin 5mg/kg. Group IV, V and VI rats were treated with 25mg/kg, 50mg/kg and 100mg/kg of Lutein. After 16 weeks, liver tissue samples were collected from all the groups of animals to evaluate the expression of PPARα and LDLR.Results: The expression of Peroxisome proliferator activated receptor α and low-density lipoprotein (LDL) receptor (LDLR) was significantly increased in Lutein treated hypercholesterolemic male wistar rats.Conclusions: The results of this study indicate that Lutein activates LDL receptor and PPARα in hypercholesterolemic male wistar rats

RESEARCH ON AYURVEDA DRUGS TOWARDS THE DRUG DEVELOPMENT FOR PLASMODIUM VIVAX MALARIA

Developing countries are more vulnerable to the Vector borne diseases, than developed countries. Incidence of Malaria is steadily increasing and number of deaths as well; is a serious problem in Africa; every five (20%) childhood deaths are due to the effects of the disease and every 30 seconds a child dies from malaria. The problem of Malaria acquired new dimensions such as resistance of vectors to chemical insecticides and drug resistance in strains of Plasmodium Vivax and Plasmodium Falciparum. These are the serious obstacles in the control of Malaria and hence there is a serious need to develop alternate strategies to control Malaria.Central Council for Research in Ayurvedic Sciences is carrying out clinical trial on different Vector Borne Diseases like Malaria, Filariasis etc since seventies. Trial carried out with herbal and herbo-mineral drugs like AYUSH-64, Saptaparnatwak ghanavati, Guduci satva, Spatika Bhasma, Kiratatiktadi compound, Parijatapatra ghanavati etc. on Plasmodium Vivax Malaria. The present paper deals with the details of those drugs and concludes the best drug for control of Malaria

Marine fisheries in Gujarat

A brief account of marine fish landings in Gujarat during 1985- 95 is given in this paper. Contribution of different gears along with the CPUE and the regionwise as well as groupwise details are also presented. The status and prospect of marine fisheries ofihe state is discussed with the aid of last 5 decades landing data

Intermittency transitions to strange nonchaotic attractors in a quasiperiodically driven Duffing oscillator

Different mechanisms for the creation of strange nonchaotic attractors (SNAs) are studied in a two-frequency parametrically driven Duffing oscillator. We focus on intermittency transitions in particular, and show that SNAs in this system are created through quasiperiodic saddle-node bifurcations (Type-I intermittency) as well as through a quasiperiodic subharmonic bifurcation (Type-III intermittency). The intermittent attractors are characterized via a number of Lyapunov measures including the behavior of the largest nontrivial Lyapunov exponent and its variance as well as through distributions of finite-time Lyapunov exponents. These attractors are ubiquitous in quasiperiodically driven systems; the regions of occurrence of various SNAs are identified in a phase diagram of the Duffing system.Comment: 24 pages, RevTeX 4, 12 EPS figure

STANDARDIZATION OF BALAMULA CHURNA (SIDA CORDIFOLIA L. ROOT POWDER)

Objective: In this study, an attempt was made to generate information based on, physicochemical parameter preliminary phytochemical screening and HPTLC data needed for proper identification and authentication of Balamula Churna. Methods: The physicochemical parameters such as water-soluble extractive, alcohol soluble extractive and loss on drying at 105 °C, total ash and acid insoluble ash were determined according to standard methods. HPTLC studies were conducted and Rf values were documented. Results: Physicochemical parameter value were documented as pH (6.81%), LOD (7.5%), water-soluble extractive value (6.32%), alcohol soluble extractive value (5.92%) total Ash (9.00%) and Acid Insoluble Ash (1.60%). Preliminary phytochemical screening reveals the presence of glycoside, alkaloid, carbohydrate, phenol, flavonoid and saponin. HPTLC screening showed the presence of significant phytoconstituents with Rf value 0.02, 0.27, 0.34 and 0.96. Conclusion: All the results obtained from this study can be helpful in evaluation quality, detection of adulteration and substitution and emphasizing the importance of standardization