151 research outputs found
Electrophysical and geoinformational methods of mapping the biological properties of peats
It is shown that the use of electrophysical methods and GIS technologies allows revealing soil coverage structure and spatial distribution of individual biological indicators, in particular, greenhouse gases production, in drained histosols (eutrophic peat soils) located in complex landscape and hydrological conditions of the Yakhroma Valley in the Moscow Region. The combination of GIS technologies and soil electrophysics made it possible to bring together the various aspects of the soil composition and functioning. Consequently, it generates easily readable βimageβ of soil in a given place and at certain times. The used approach is based on the idea that the electrical resistance of soils, associated with the density of mobile charges (cations and anions of soil absorbing complex and solution), is formed under the influence of soil-forming processes and it is an integral indicator of a wide range of soil properties. Taking into account that the evolution and degradation of peatlands after their drainage is a microbiological process primarily, we paid special attention to the research in this area. The experience has been obtained in the mapping of the microbial formation of CO2, N2O and CH4 in peat soils. On the one hand, it allows estimating the current intensity of organic matter decomposition and losses of nitrogen and carbon by peat soils of different botanical composition, terms and methods of meliorations, and on the other hand, to determine the contribution of these soils to the greenhouse effect. It was established that the electrical resistance of the soil, basal, substrate-induced respiration and denitrification activity (specific form of anaerobic respiration) depend on the same set of soil properties and correlate with each other within the studied area. The high speed and productivity of electrophysical methods allow them to be used for primary soil diagnostics, selection of key points for further research, detailing the cartographic contours and refining the calculations of greenhouse gas fluxes from large areas
Diversity of early flowering plants of the Ulytau mountains (Central Kazakhstan)
Early flowering plants (ephemers and ephemeroids) are an important component of the biosystem of steppes and deserts. These species form perennial pasture communities, for early grazing. The present work was conducted to evaluate the floristic checklist and ecological uniqueness of early flowering plants of Central Kazakhstan, in the forest-steppe regions of Em-Bulak region and Edige mountains, during 2021 and 2022. A total of 26 species of ephemers and ephemeroids were recorded, which belong to 16 families: Liliaceae β 3 species, Asteraceae β 3 species, Ranunculaceae β 3 species, Rosaceae β 3 species, Brassicaceae β 2 species, Boraginaceae β 2 species, the other families are represented by one species. According to ecomorphological characteristics: 8 species (31%) belong to the xerophyte group, 6 (23%) to the xeromesophyte group, 7 (27%) to the mesoxerophyte group and 5 (19%) to the mesophyte group. Also, as a result of our research we found two species of plants which are included in the Red Book of the Republic of Kazakhstan β Pulsatilla patens (L.) Mill. and Tulipa patens Agardh. ex Schult. f. The data obtained can be used for environmental monitoring and issues of rational nature management of wild plants of Central Kazakhstan
Increase professional skills of teachers of higher professional institutions in the field of physical culture
The teaching of physical culture at the University requires the teacher not only ownership of professional knowledge, abilities and skills, high physical and technical preparednessΠΡΠ΅ΠΏΠΎΠ΄Π°Π²Π°Π½ΠΈΠ΅ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΊΡΠ»ΡΡΡΡΡ Π² Π²ΡΠ·Π΅ ΡΡΠ΅Π±ΡΠ΅Ρ ΠΎΡ ΠΏΡΠ΅ΠΏΠΎΠ΄Π°Π²Π°ΡΠ΅Π»Ρ Π½Π΅ ΡΠΎΠ»ΡΠΊΠΎ Π²Π»Π°Π΄Π΅Π½ΠΈΡ ΠΏΡΠΎΡΠ΅ΡΡΠΈΠΎΠ½Π°Π»ΡΠ½ΡΠΌΠΈ Π·Π½Π°Π½ΠΈΡΠΌΠΈ, ΡΠΌΠ΅Π½ΠΈΡΠΌΠΈ ΠΈ Π½Π°Π²ΡΠΊΠ°ΠΌΠΈ, Π²ΡΡΠΎΠΊΠΎΠΉ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΈ ΡΠ΅Ρ
Π½ΠΈΡΠ΅ΡΠΊΠΎΠΉ ΠΏΠΎΠ΄Π³ΠΎΡΠΎΠ²Π»Π΅Π½Π½ΠΎΡΡΡ
Performance evaluation of physical exercise and recreational activities of the Samara State University of means of communication
Π ΡΠ°Π±ΠΎΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ Π²ΠΊΠ»Π°Π΄ ΡΠΈΠ·ΠΊΡΠ»ΡΡΡΡΠ½ΠΎ-ΠΎΠ·Π΄ΠΎΡΠΎΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ Π² Π‘Π°ΠΌΠΠ£ΠΠ‘, ΡΠ΅Π»ΠΈ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΎΡΠΏΠΈΡΠ°Π½ΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠΎΡΠ΅ΡΡ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π·Π°Π½ΡΡΠΈΠΉ Π½Π° ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΠΎΠΌ ΠΏΡΠΈΠΌΠ΅ΡΠ΅In this work the contribution of sports recreational activities in SamGUPS, physical education, as well as classes on specific exampl
The effectiveness of physical culture and health-improving activity of the Samara state University of transport
Π ΡΠ°Π±ΠΎΡΠ΅ ΡΠ°ΡΡΠΌΠ°ΡΡΠΈΠ²Π°ΡΡΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½ΠΎΡΡΡ ΡΠΈΠ·ΠΊΡΠ»ΡΡΡΡΠ½ΠΎ-ΠΎΠ·Π΄ΠΎΡΠΎΠ²ΠΈΡΠ΅Π»ΡΠ½ΠΎΠΉ Π΄Π΅ΡΡΠ΅Π»ΡΠ½ΠΎΡΡΠΈ ΠΊΠ°ΡΠ΅Π΄ΡΡ Β«Π€ΠΠ‘Β», ΡΠ΅Π»ΠΈ ΡΠΈΠ·ΠΈΡΠ΅ΡΠΊΠΎΠ³ΠΎ Π²ΠΎΡΠΏΠΈΡΠ°Π½ΠΈΡ, Π° ΡΠ°ΠΊΠΆΠ΅ ΠΏΡΠΎΡΠ΅ΡΡ ΠΎΡΠ³Π°Π½ΠΈΠ·Π°ΡΠΈΠΈ Π·Π°Π½ΡΡΠΈΠΉ Π½Π° ΠΊΠΎΠ½ΠΊΡΠ΅ΡΠ½ΠΎΠΌ ΠΏΡΠΈΠΌΠ΅ΡΠ΅, ΠΏΡΠΎΠ²Π΅Π΄Π΅Π½ SWOT-Π°Π½Π°Π»ΠΈΠ·The paper examines the effectiveness of physical culture and health-improving activities of the Department of Β«PESΒ», the objectives of physical education, as well as the process of organization of classes in a specific example, carried out a SWOT-analysi
Preferential CO oxidation in hydrogen (PROX) on ceria-supported catalysts PART II. Oxidation states and surface species on Pd/CeO2 under reaction conditions, suggested reaction mechanism
The aim of the PROX reaction is to reduce the CO content of hydrogen feed to proton-exchange membrane fuel cells (PEMFCs) by selective oxidation of CO in the presence of excess hydrogen. Both Pt and Pd on ceria are active in CO oxidation (without hydrogen), whereas Pd is poorly active in the presence of hydrogen. In this paper we explore the reasons for such behavior, using the same techniques for Pd/CeO2 as used for Pt/CeO2 in Part I: catalytic tests, in situ DRIFTS, high-pressure XPS, HRTEM, and TDS. We also examine the reaction mechanism of CO oxidation (without hydrogen), which does not occur via exactly the same mechanism on Pt and Pd/CeO2 catalysts. In the presence of hydrogen (PROX) at low temperature (T = 350β380 K), the formation of Pd Ξ²-hydride was confirmed by high-pressure in situ XPS. Its formation greatly suppressed the possibility of CO oxidation, because oxygen both from gas-phase and support sites reacted rapidly with hydride H to form water, which readily desorbed from Pd. Nevertheless, CO adsorption was not hampered here. These entities transformed mainly to surface formate and formyl (βCHO) species instead of oxidation as observed by DRIFTS. The participation of a low-temperature waterβgas shift type reaction proposed for the platinum system (see Part I) was hindered. Increasing temperature led to decomposition of the hydride phase and a parallel increase in the selectivity toward CO oxidation. This still remained lower on Pd/CeO2 than on Pt/CeO2, however
Russian registry of Infliximab.Impact of therapy on the functional status of patients with rheumatoid arthritis
Objective. To evaluate the functional state of rheumatoid arthritis (RA) patients receiving Infliximab therapy (IF) in real clinical practice and its efficiency. Subjects and methods. The analysis covered 225 patients receiving IF therapy, the follow-up duration in whom was 54 weeks. Disease activity was estimated by the DAS 28 index; functional status was assessed according to the Health Assessment Questionnaire (HAQ). The authors made an analysis of a Per-Protocol (PP) population (n = 154) at 54 weeks of treatment and an analysis that could consider the results of treatment (by the ACR and EULAR criteria) in patients who had been withdrawn before the control time - a LOCF (Last Observation Carried Forward analysis) population. Results. The mean age of the patients was 47.6Β±11.4 years; the duration of the disease was 7.8Β±6.4 years; DAS 28 activity scores were 6.6Β±1.1; the majority of patients had significant functional impairments (HAQ scores of 2.0Β±0.7), 86.7% of the patients had extraarticular manifestations; 79.6% were found to have rheumatoid factor (RF); the patients received an average of > 2 disease-modifying antirheumatic drugs (DMARDs). After 2 week-therapy, there was a reduction in RA activity by DAS 28 index in both the PP (from 6.7Β±1.1 to 4.0Β±1.4) and LOCF (6.6Β±1.1 and 4.2Β±1.4; p < 106) populations. Drug-induced remission (DAS 28 < 2.6) at 54 weeks was observed in 16.9 and 15.1% of the patients, respectively. Functional improvement was noted in the PP population: HAQ decreased from 2.0Β±0.7 to 1.7Β±0.7 scores by week 2; its reduction continued until week 14 (p < 0.05), by remaining stable later on. HAQ dropped from 2.0Β±0.7 to 1.2Β±0.7 scores in the LOCF population. At 54 weeks, normal population values of functional activity were achieved in 16.4%. Log regression analysis in the LOCF population indicated that the previous use of DMARDs and a short history of the disease were predictors of an ACR70 response to IF therapy [OR=1.61 (1.13-2.30), p = 0.008 and OR = 0.91 (0.84-0.98), p = 0.018, respectively]. RF seronegativity was a predictor for achievement of low RA activity [OR = 0.44 (0.23-0.84)]. The previous use of glucocorticoids failed to increase the probability of a good response to IF therapy and achievement of clinical remission [OR = 0.26 (0.11-0.60), p = 0.001]. Conclusion. Therapy with IF in combination with methotrexate or other DMARDs reduces RA activity and improves the functional capacities of patients with RA in real clinical practice
Π‘ΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ Π°ΡΠΏΠ΅ΠΊΡΡ ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ (ΠΎΠ±Π·ΠΎΡ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ)
The literature review highlights modern ideas about the pathogenesis, pathomorphology, and clinical manifestations of central nervous system damage in patients with HIV infection, and also touches on the problems of diagnosis and treatment of these opportunistic infections. Particular attention should be paid to patients with severe immunodeficiency (CD4+T-lymphocyte count < 200 cl/ml) due to the high risk of secondary diseases of the central nervous system. Along with the etiological verification of opportunistic diseases of the central nervous system, magnetic resonance imaging of the brain is important at the initial stage of diagnosis, with the help of which it is possible to identify changes in the brain substance characteristic of certain pathogens. In addition to the basic etiotropic therapy of opportunistic infections in HIV patients, effective antiretroviral therapy and its index of penetration into the central nervous system play a crucial role.Π ΠΎΠ±Π·ΠΎΡΠ΅ Π»ΠΈΡΠ΅ΡΠ°ΡΡΡΡ ΠΎΡΠ²Π΅ΡΠ°ΡΡΡΡ ΡΠΎΠ²ΡΠ΅ΠΌΠ΅Π½Π½ΡΠ΅ ΠΏΡΠ΅Π΄ΡΡΠ°Π²Π»Π΅Π½ΠΈΡ ΠΎ ΠΏΠ°ΡΠΎΠ³Π΅Π½Π΅Π·Π΅, ΠΏΠ°ΡΠΎΠΌΠΎΡΡΠΎΠ»ΠΎΠ³ΠΈΠΈ, ΠΊΠ»ΠΈΠ½ΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΏΡΠΎΡΠ²Π»Π΅Π½ΠΈΡΡ
ΠΏΠΎΡΠ°ΠΆΠ΅Π½ΠΈΡ ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ, Π° ΡΠ°ΠΊΠΆΠ΅ Π·Π°ΡΡΠ°Π³ΠΈΠ²Π°ΡΡΡΡ ΠΏΡΠΎΠ±Π»Π΅ΠΌΡ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΈ Π»Π΅ΡΠ΅Π½ΠΈΡ Π΄Π°Π½Π½ΡΡ
ΠΎΠΏΠΏΠΎΡΡΡΠ½ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ. ΠΡΠΎΠ±ΠΎΠ΅ Π²Π½ΠΈΠΌΠ°Π½ΠΈΠ΅ ΡΠ»Π΅Π΄ΡΠ΅Ρ ΡΠ΄Π΅Π»ΡΡΡ ΠΏΠ°ΡΠΈΠ΅Π½ΡΠ°ΠΌ Ρ ΡΡΠΆΠ΅Π»ΡΠΌ ΠΈΠΌΠΌΡΠ½ΠΎΠ΄Π΅ΡΠΈΡΠΈΡΠΎΠΌ (ΠΊΠΎΠ»ΠΈΡΠ΅ΡΡΠ²ΠΎ CD4+Π’-Π»ΠΈΠΌΡΠΎΡΠΈΡΠΎΠ² β€ 200 ΠΊΠ»/ΠΌΠΊΠ») Π² ΡΠ²ΡΠ·ΠΈ Ρ Π²ΡΡΠΎΠΊΠΈΠΌ ΡΠΈΡΠΊΠΎΠΌ ΡΠ°Π·Π²ΠΈΡΠΈΡ Π²ΡΠΎΡΠΈΡΠ½ΡΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ. ΠΠ°ΡΡΠ΄Ρ Ρ ΡΡΠΈΠΎΠ»ΠΎΠ³ΠΈΡΠ΅ΡΠΊΠΎΠΉ Π²Π΅ΡΠΈΡΠΈΠΊΠ°ΡΠΈΠ΅ΠΉ ΠΎΠΏΠΏΠΎΡΡΡΠ½ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΠΎΠΉ Π½Π΅ΡΠ²Π½ΠΎΠΉ ΡΠΈΡΡΠ΅ΠΌΡ, Π²Π°ΠΆΠ½ΠΎΠ΅ Π·Π½Π°ΡΠ΅Π½ΠΈΠ΅ Π½Π° Π½Π°ΡΠ°Π»ΡΠ½ΠΎΠΌ ΡΡΠ°ΠΏΠ΅ Π΄ΠΈΠ°Π³Π½ΠΎΡΡΠΈΠΊΠΈ ΠΈΠΌΠ΅Π΅Ρ ΠΌΠ°Π³Π½ΠΈΡΠ½ΠΎ-ΡΠ΅Π·ΠΎΠ½Π°Π½ΡΠ½Π°Ρ ΡΠΎΠΌΠΎΠ³ΡΠ°ΡΠΈΡ Π³ΠΎΠ»ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°, Ρ ΠΏΠΎΠΌΠΎΡΡΡ ΠΊΠΎΡΠΎΡΠΎΠΉ ΠΌΠΎΠΆΠ½ΠΎ Π²ΡΡΠ²ΠΈΡΡ Ρ
Π°ΡΠ°ΠΊΡΠ΅ΡΠ½ΡΠ΅ Π΄Π»Ρ ΠΎΠΏΡΠ΅Π΄Π΅Π»Π΅Π½Π½ΡΡ
Π²ΠΎΠ·Π±ΡΠ΄ΠΈΡΠ΅Π»Π΅ΠΉ ΠΈΠ·ΠΌΠ΅Π½Π΅Π½ΠΈΡ Π² Π²Π΅ΡΠ΅ΡΡΠ²Π΅ Π³ΠΎΠ»ΠΎΠ²Π½ΠΎΠ³ΠΎ ΠΌΠΎΠ·Π³Π°. ΠΠΎΠΌΠΈΠΌΠΎ Π±Π°Π·ΠΎΠ²ΠΎΠΉ ΡΡΠΈΠΎΡΡΠΎΠΏΠ½ΠΎΠΉ ΡΠ΅ΡΠ°ΠΏΠΈΠΈ ΠΎΠΏΠΏΠΎΡΡΡΠ½ΠΈΡΡΠΈΡΠ΅ΡΠΊΠΈΡ
ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠΉ, Ρ Π±ΠΎΠ»ΡΠ½ΡΡ
ΠΠΠ§-ΠΈΠ½ΡΠ΅ΠΊΡΠΈΠ΅ΠΉ ΡΠ΅ΡΠ°ΡΡΡΡ ΡΠΎΠ»Ρ ΠΈΠ³ΡΠ°ΡΡ ΡΡΡΠ΅ΠΊΡΠΈΠ²Π½Π°Ρ Π°Π½ΡΠΈΡΠ΅ΡΡΠΎΠ²ΠΈΡΡΡΠ½Π°Ρ ΡΠ΅ΡΠ°ΠΏΠΈΡ ΠΈ Π΅Π΅ ΠΈΠ½Π΄Π΅ΠΊΡ ΠΏΡΠΎΠ½ΠΈΠΊΠ½ΠΎΠ²Π΅Π½ΠΈΡ Π² ΡΠ΅Π½ΡΡΠ°Π»ΡΠ½ΡΡ Π½Π΅ΡΠ²Π½ΡΡ ΡΠΈΡΡΠ΅ΠΌΡ
CLINICAL TRIAL OF THE PANDEMIC INFLUENZA MONOVALENT VACCINE PANDEFLU
Abstract. Evaluation of reactogenicity, safety and immunogenicity of the inactivated subunit influenza vaccine adsorbed monovalent (Pandeflu) on the base of strain A/California/7/2009 (H1N1v) was conducted in 70 volunteers aged 18β60 years immunized by one or two doses. A clinical trial of the vaccine Pandeflu was conducted in the St.Petersburg Institute of Influenza. The study group included 38 women (54,3%) and 32 men (45,7%). The average age of women was 38.2 years, men β 26.9 years, mean age of all volunteers was equal to 31.7 years. This group of volunteers was randomized in 2 subgroups. The first subgroup of 50 volunteers was vaccinated with Pandeflu, but the second one of 20 volunteers was given a placebo. The strong and moderate local and systemic reactions were not observed. All local (6 volunteers) and systemic (6 volunteers) reactions were recorded after ithout any medical care. It proves the good tolerability and low reactogenicity of vaccine Pandeflu. Indicators of clinical and biochemical blood tests, a general analysis of urine during the study period were within normal limits. In the study of the immunogenicity it has been shown that after a single injection of vaccine the first vaccination. All these reactions were mild and transient and disappeared wPandeflu the seroconversion rate reached 68%, but the level of seroprotection was 52%. The multiplication factor of the geometric mean antibody titer increase in serum reached a value of 5.8. Conducting of immunization with two doses of vaccine with the interval of 28 days increases the immunogenicity: the level of seroconversion rate increases up to 96%, but the level of seroprotection β up to 74%, seroconversion factor β up to 10.8. These data confirm high immunogenic potential vaccine in case of single dose as well as double doses administration
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