3 research outputs found
The role of General Assembly of the UN in the fight against apartheid
This thesis is focused on the regime of apartheid in South Africa and the action of the United Nations within the efforts of its dismantling. The aim of this thesis is to evaluate the merits of General Assembly’s operations in the combat against apartheid. The evaluation is based on the analysis of resolutions issued by General Assembly and the historical description leading to the downfall of apartheid.Tato bakalářská práce se zabývá režimem apartheidu v Jihoafrické republice a působením Organizace Spojených národů v rámci jeho rozkladu. Cílem práce je zhodnocení zásluh činnosti Valného shromáždění v boji za odstranění apartheidu. Zhodnocení je provedeno na základě analýzy rezolucí vydaných Valným shromážděním a historické deskripce okolností vedoucí k pádu režimu
The Venezuelan Migration Wave and its Impact on Colombia
The thesis deals with the effects of the Venezuelan migration wave on Colombia. The aim of the thesis was to find out what impact the Venezuelan migration crisis has had on the situation in Colombia and what is the position of the Colombian government in relation to it. In order to answer these research questions, a qualitative content analysis was applied, which examined data provided by international organizations, political institutions or Colombian government authorities describing the current situation in the country. The main theoretical concept that this thesis uses as its basis is the push-pull theory of migration, which explains migration based on the mechanism of "push" and "pull" factors that motivate the population to move. As a result of the analysis of the examined data, the hypothesis was confirmed, which assumed that the migration crisis has had a negative impact on the Colombian national situation, specifically in the institutional, economic and social spheres. The results of the content analysis revealed significant negative impacts in all three mentioned spheres and subsequently the possible future development was outlined. Furthermore, the results of the analysis reveal Colombia's historical and current approach to Venezuelan migrants and confirm the hypothesis that the..
Synthesis of Tyrosol and Hydroxytyrosol Glycofuranosides and Their Biochemical and Biological Activities in Cell-Free and Cellular Assays
Tyrosol (T) and hydroxytyrosol (HOT) and their glycosides are promising candidates for applications in functional food products or in complementary therapy. A series of phenylethanoid glycofuranosides (PEGFs) were synthesized to compare some of their biochemical and biological activities with T and HOT. The optimization of glycosylation promoted by environmentally benign basic zinc carbonate was performed to prepare HOT α-L-arabino-, β-D-apio-, and β-D-ribofuranosides. T and HOT β-D-fructofuranosides, prepared by enzymatic transfructosylation of T and HOT, were also included in the comparative study. The antioxidant capacity and DNA-protective potential of T, HOT, and PEGFs on plasmid DNA were determined using cell-free assays. The DNA-damaging potential of the studied compounds for human hepatoma HepG2 cells and their DNA-protective potential on HepG2 cells against hydrogen peroxide were evaluated using the comet assay. Experiments revealed a spectrum of different activities of the studied compounds. HOT and HOT β-D-fructofuranoside appear to be the best-performing scavengers and protectants of plasmid DNA and HepG2 cells. T and T β-D-fructofuranoside display almost zero or low scavenging/antioxidant activity and protective effects on plasmid DNA or HepG2 cells. The results imply that especially HOT β-D-fructofuranoside and β-D-apiofuranoside could be considered as prospective molecules for the subsequent design of supplements with potential in food and health protection