720 research outputs found
Enterococcus cecorum septicemia in a malnourished adult patient
Enterococcus cecorum, a species typically isolated from chicken, pigs, calves, horses, ducks, cats, dogs, and canaries, was isolated from the blood of a patient with severe septicemia. The isolate was identified by conventional biochemical tests. Identity asEnterococcus cecorum was confirmed by SDS-PAGE analysis of whole cell protein. This is the first report of the isolation ofEnterococcus cecorum in a clinical settin
Structuur van de bouwvoor op het grondbewerkingssystemenproefveld Ws 38 op de proefboerderij Westmaas, in de jaren 1971 t/m 1975
Comment on 'No major role for glutathione S-transferase gene polymorphisms in sensitization to para-phenylenediamine and other xenobiotics:a study of association and a meta-analysis'
An automated workflow for high throughput MLVA using the BioNumerics® software, able to deal with varying experimental settings
Comparative genomics among members of the Streptococcus bovis/Streptococcus equinus complex
Background: Today, only one streptococcal species, i.e. Streptococcus thermophilus is recognized as food-grade. Interestingly, other
streptococci like Streptococcus macedonicus and Streptococcus infantarius belonging to the Streptococcus bovis/Streptococcus
equinus complex (SBSEC) are also found in food matrices. However, these species are phylogenetically related to Streptococcus
gallolyticus and Streptococcus pasteurianus that have been linked to endocarditis, bacteremia and colon cancer.
Objectives: To compare the available genomes of the members of the SBSEC in order to shed light onto their evolution and
phylogenetic relation and to assess in silico their pathogenic potential.
Methods: Comparative genomics analysis including full chromosome and CDS alignments, whole genome phylogeny and evaluation
of gene content (e.g. core genome, singletons, etc.) was performed with appropriate bioinformatics tools.
Conclusions: Despite the fact that the four species of the SBSEC were found tightly related based on whole genome phylogeny, there
were two different patterns of evolution among them. Streptococcus pasteurianus, S. macedonicus and S. infantarius seem to have
undergone a reductive evolution process that resulted in significantly diminished genome sizes and increased percentages of
potential pseudogenes when compared to S. gallolyticus. In addition, S. pasteurianus, S. macedonicus and S. infantarius seem to
have lost several genes previously linked to the ability of S. gallolyticus to survive in the gastrointestinal tract of herbivores and to
its pathogenicity. Our findings indicate differences in the ecological niche and the pathogenic potential among the four species
Neuropsychiatric symptoms in patients with dementia in primary care: a study protocol
BACKGROUND: Neuropsychiatric symptoms (NPS) frequently occur in patients with dementia. To date, prospective studies on the course of NPS have been conducted in patients with dementia in clinical centers or psychiatric services. The primary goal of this study is to investigate the course of NPS in patients with dementia and caregiver distress in primary care. We also aim to detect determinants of both the course of NPS in patients with dementia and informal caregiver distress in primary care. METHODS/DESIGN: This is a prospective observational study on the course of NPS in patients with dementia in primary care. Thirty-seven general practitioners (GPs) in 18 general practices were selected based on their interest in participating in this study. We will retrieve electronic medical files of patients with dementia from these general practices. Patients and caregivers will be followed for 18 months during the period January 2012 to December 2013. Patient characteristics will be collected at baseline. Time to death or institutionalization will be measured. Co-morbidity will be assessed using the Charlson index. Psychotropic drug use and primary and secondary outcome measures will be measured at 3 assessments, baseline, 9 and 18 months. The primary outcome measures are the Neuropsychiatric Inventory score for patients with dementia and the Sense of Competence score for informal caregivers. In addition to descriptive analyses frequency parameters will be computed. Univariate analysis will be performed to identify determinants of the course of NPS and informal caregiver distress. All determinants will then be tested in a multivariate regression analysis to determine their unique contribution to the course of NPS and caregiver distress. DISCUSSION: The results of this study will provide data on the course of NPS, which is clinically important for prognosis. The data will help GPs and other professionals in planning follow-up visits and in the timing for offering psycho-education, psychosocial interventions and the provision of care. In addition, these data will enlarge health professionals’ awareness of NPS in their patients with dementia
International Committee on Systematics of Prokaryotes Subcommittee on the Taxonomy of Bifidobacterium, Lactobacillus and related organisms. Minutes of the closed meeting by videoconference, 3 September 2020
International Committee on Systematics of Prokaryotes
Subcommittee on the Taxonomy of Bifidobacterium, Lactobacillus
and related organisms. Minutes of the closed meeting by
videoconference, 3 September 202
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