701 research outputs found
Evolution of the N ion Jaynes-Cummings model beyond the standard rotating wave approximation
A unitary transformation of the N-ion Jaynes-Cummings hamiltonian is
proposed. It is shown that any approximate expression of the evolution operator
associated with the transformed hamiltonian retains its validity independently
from the intensity of the external driving field. In particular, using the
rotating wave approximation, one obtains a solution for the N-ion
Jaynes-Cummings model which improves the standard rotating wave approximation
solution.Comment: Presented at the Wigner Centennial Conference (Pecs, Hungary, July
2002) (to appear on Journal of Optics B, provisionally scheduled for June
2003 issue
Full characterization of Gaussian bipartite entangled states by a single homodyne detector
We present the full experimental reconstruction of Gaussian entangled states
generated by a type--II optical parametric oscillator (OPO) below threshold.
Our scheme provides the entire covariance matrix using a single homodyne
detector and allows for the complete characterization of bipartite Gaussian
states, including the evaluation of purity, entanglement and nonclassical
photon correlations, without a priori assumptions on the state under
investigation. Our results show that single homodyne schemes are convenient and
robust setups for the full characterization of OPO signals and represent a tool
for quantum technology based on continuous variable entanglement.Comment: 4 pages, 3 figures, slightly longer version of published PR
Homodyne extimation of quantum states purity by exploiting covariant uncertainty relation
We experimentally verify uncertainty relations for mixed states in the
tomographic representation by measuring the radiation field tomograms, i.e.
homodyne distributions. Thermal states of single-mode radiation field are
discussed in details as paradigm of mixed quantum state. By considering the
connection between generalised uncertainty relations and optical tomograms is
seen that the purity of the states can be retrieved by statistical analysis of
the homodyne data. The purity parameter assumes a relevant role in quantum
information where the effective fidelities of protocols depend critically on
the purity of the information carrier states. In this contest the homodyne
detector becomes an easy to handle purity-meter for the state on-line with a
running quantum information protocol.Comment: accepted for publication into Physica Script
Tapentadol in cancer pain management: a prospective open-label study.
OBJECTIVES:
The aim of this prospective, open-label study was to evaluate the efficacy and tolerability of tapentadol (TP) in the management of cancer pain.
METHODS:
A 4 weeks' prospective study was carried out in 50 opioid-naive cancer patients with moderate-severe pain. Each patient initially received twice-daily doses of slow-release TP 50 mg. Doses were then managed to maintain adequate relief or dose-limiting toxicity, on the basis of the clinical response. The following parameters were recorded at weekly intervals for 4 weeks: pain and opioid-related adverse effects, quality of life measured with the Spitzer score, TP escalation index percent (TPEI%) and TP escalation index in mg (TPEImg), calculated at the end of the study, pain mechanisms, and PainDETECT at baseline.
RESULTS:
Of 50 patients, 39 completed the entire study and 11 discontinued the treatment for different reasons. Pain intensity significantly decreased from baseline to all the week intervals (p < 0.0005), and adverse effects did not changed significantly, while quality of life improved. TP escalation indexes were low and no relationship was found with age, gender, and pain mechanisms.
CONCLUSION:
Tapentalol started in doses of 100 mg/day was well-tolerated and effective in opioid-naive patients with cancer pain, regardless of the pain mechanism. It can be considered as a flexible drug to be used in patients with moderate-severe pain.
LIMITATIONS:
This was an open-label study for exploratory purposes. Data should be confirmed in controlled studies with a larger number of patient
Optical response of a misaligned and suspended Fabry-Perot cavity
The response to a probe laser beam of a suspended, misaligned and detuned
optical cavity is examined. A five degree of freedom model of the fluctuations
of the longitudinal and transverse mirror coordinates is presented. Classical
and quantum mechanical effects of radiation pressure are studied with the help
of the optical stiffness coefficients and the signals provided by an FM
sideband technique and a quadrant detector, for generic values of the product
of the fluctuation frequency times the cavity round trip. A
simplified version is presented for the case of small misalignments. Mechanical
stability, mirror position entanglement and ponderomotive squeezing are
accommodated in this model. Numerical plots refer to cavities under test at the
so-called Pisa LF facility.Comment: 14 pages (4 figures) submitted to Phys. Rev.
Major loss of coralline algal diversity in response to ocean acidification
Calcified coralline algae are ecologically important in rocky habitats in the marine photic zone worldwide and there is growing concern that ocean acidification will severely impact them. Laboratory studies of these algae in simulated ocean acidification conditions have revealed wide variability in growth, photosynthesis and calcification responses, making it difficult to assess their future biodiversity, abundance and contribution to ecosystem function. Here, we apply molecular systematic tools to assess the impact of natural gradients in seawater carbonate chemistry on the biodiversity of coralline algae in the Mediterranean and the NW Pacific, link this to their evolutionary history and evaluate their potential future biodiversity and abundance. We found a decrease in the taxonomic diversity of coralline algae with increasing acidification with more than half of the species lost in high pCO2 conditions. Sporolithales is the oldest order (Lower Cretaceous) and diversified when ocean chemistry favoured low Mg calcite deposition; it is less diverse today and was the most sensitive to ocean acidification. Corallinales were also reduced in cover and diversity but several species survived at high pCO2; it is the most recent order of coralline algae and originated when ocean chemistry favoured aragonite and high Mg calcite deposition. The sharp decline in cover and thickness of coralline algal carbonate deposits at high pCO2 highlighted their lower fitness in response to ocean acidification. Reductions in CO2 emissions are needed to limit the risk of losing coralline algal diversity
Displacement power spectrum measurement of a macroscopic optomechanical system at thermal equilibrium
The mirror relative motion of a suspended Fabry-Perot cavity is studied in
the frequency range 3-10 Hz. The experimental measurements presented in this
paper, have been performed at the Low Frequency Facility, a high finesse
optical cavity 1 cm long suspended to a mechanical seismic isolation system
identical to that one used in the VIRGO experiment. The measured relative
displacement power spectrum is compatible with a system at thermal equilibrium
within its environmental. In the frequency region above 3 Hz, where seismic
noise contamination is negligible, the measurement distribution is stationary
and Gaussian, as expected for a system at thermal equilibrium. Through a simple
mechanical model it is shown that: applying the fluctuation dissipation theorem
the measured power spectrum is reproduced below 90 Hz and noise induced by
external sources are below the measurement.Comment: 11 pages, 9 figures, 2 tables, to be submitte
Characterization of bipartite states using a single homodyne detector
We suggest a scheme to reconstruct the covariance matrix of a two-mode state
using a single homodyne detector plus a polarizing beam splitter and a
polarization rotator. It can be used to fully characterize bipartite Gaussian
states and to extract relevant informations on generic states.Comment: 7 pages, 1 figur
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