The 70 S monosome accumulation and in vitro initiation complex formation by Escherichia coli ribosomes at 5 C

The inhibition of translation which is observed after shifting Escherichia coli to low temperature was investigated. 70 S ribosomes were isolated from E. coli 8 hours after a shift to 5 C synthesized protein in the absence of added mRNA (i.e., endogenous protein synthesis by 70 S monosomes) at a rate which was three times greater than the rate of endogenous protein synthesis by 70 S ribosomes which were isolated at the time of the shift to 5 C. Calculations based on the rates of endogenous protein synthesis and polyphenylalanine synthesis indicate that 70 S monosomes comprise only 0.1% of the total E. coli 70 S ribosome population after 8 hours at 5 c. Experiments designed to test initiation complex formation on ApUpG or formaldehyde treated MS-2 viral RNA demonstrated that, although the rate of formation of 30 S initiation complexes was not inhibited, the rate of formation of active 70 S initiation complexes, able to react with puromycin, was inhibited to a great extent at 5 C. A model depicting the effects of low temperature on the E. coli translation system is proposed

Agricultural Market Structure, Generic Advertising, and Welfare

This analysis begins with a definition and discussion of productive advertising. Then, following Dixit and Norman, persuasive advertising is used to study the welfare effects of generic advertising by marketing orders. The study first examines horizontal competition when the competing advertiser is a monopoly, and results show that the socially optimal level of advertising for a competitive marketing order is positive only if advertising raises monopoly output. Next, advertising choices of a marketing order which sells its output to a monopolistic distributor are considered. If the distributor is a monopolist, then marketing order advertising raises welfare. This finding is in marked contrast to the results for the horizontal case studied by Dixit and Norman.advertising, market structure, welfare, Marketing,

General Kerr-NUT-AdS Metrics in All Dimensions

The Kerr-AdS metric in dimension D has cohomogeneity [D/2]; the metric components depend on the radial coordinate r and [D/2] latitude variables \mu_i that are subject to the constraint \sum_i \mu_i^2=1. We find a coordinate reparameterisation in which the \mu_i variables are replaced by [D/2]-1 unconstrained coordinates y_\alpha, and having the remarkable property that the Kerr-AdS metric becomes diagonal in the coordinate differentials dy_\alpha. The coordinates r and y_\alpha now appear in a very symmetrical way in the metric, leading to an immediate generalisation in which we can introduce [D/2]-1 NUT parameters. We find that (D-5)/2 are non-trivial in odd dimensions, whilst (D-2)/2 are non-trivial in even dimensions. This gives the most general Kerr-NUT-AdS metric in $D$ dimensions. We find that in all dimensions D\ge4 there exist discrete symmetries that involve inverting a rotation parameter through the AdS radius. These symmetries imply that Kerr-NUT-AdS metrics with over-rotating parameters are equivalent to under-rotating metrics. We also consider the BPS limit of the Kerr-NUT-AdS metrics, and thereby obtain, in odd dimensions and after Euclideanisation, new families of Einstein-Sasaki metrics.Comment: Latex, 24 pages, minor typos correcte

Extremal Black Hole/CFT Correspondence in (Gauged) Supergravities

We extend the investigation of the recently proposed Kerr/CFT correspondence to large classes of rotating black hole solutions in gauged and ungauged supergravities. The correspondence, proposed originally for four-dimensional Kerr black holes, asserts that the quantum states in the near-horizon region of an extremal rotating black hole are holographically dual to a two-dimensional chiral theory whose Virasoro algebra arises as an asymptotic symmetry of the near-horizon geometry. In fact in dimension D there are [(D-1)/2] commuting Virasoro algebras. We consider a general canonical class of near-horizon geometries in arbitrary dimension D, and show that in any such metric, the [(D-1)/2] central charges each imply, via the Cardy formula, a microscopic entropy that agrees with the Bekenstein-Hawking entropy of the associated extremal black hole. In the remainder of the paper we show for most of the known rotating black hole solutions of gauged supergravity, and for the ungauged supergravity solutions with four charges in D=4 and three charges in D=5, that their extremal near-horizon geometries indeed lie within the canonical form. This establishes that in all these examples, the microscopic entropies of the dual CFTs agree with the Bekenstein-Hawking entropies of the extremal rotating black holes.Comment: 32 pages, references added and minor typos fixe

Brane Worlds in Collision

We obtain an exact solution of the supergravity equations of motion in which the four-dimensional observed universe is one of a number of colliding D3-branes in a Calabi-Yau background. The collision results in the ten-dimensional spacetime splitting into disconnected regions, bounded by curvature singularities. However, near the D3-branes the metric remains static during and after the collision. We also obtain a general class of solutions representing $p$-brane collisions in arbitrary dimensions, including one in which the universe ends with the mutual annihilation of a positive-tension and negative-tension 3-brane.Comment: RevTex, 4 pages, 1 figure, typos and minor errors correcte

Entanglement distribution by an arbitrarily inept delivery service

We consider the scenario where a company C manufactures in bulk pure entangled pairs of particles, each pair intended for a distinct pair of distant customers. Unfortunately, its delivery service is inept - the probability that any given customer pair receives its intended particles is S, and the customers cannot detect whether an error has occurred. Remarkably, no matter how small S is, it is still possible for C to distribute entanglement by starting with non-maximally entangled pairs. We determine the maximum entanglement distributable for a given S, and also determine the ability of the parties to perform nonlocal tasks with the qubits they receive.Comment: 5 pages, 3 figures. v2 includes minor change

Adaptive Optical Phase Estimation Using Time-Symmetric Quantum Smoothing

Quantum parameter estimation has many applications, from gravitational wave detection to quantum key distribution. We present the first experimental demonstration of the time-symmetric technique of quantum smoothing. We consider both adaptive and non-adaptive quantum smoothing, and show that both are better than their well-known time-asymmetric counterparts (quantum filtering). For the problem of estimating a stochastically varying phase shift on a coherent beam, our theory predicts that adaptive quantum smoothing (the best scheme) gives an estimate with a mean-square error up to $2\sqrt{2}$ times smaller than that from non-adaptive quantum filtering (the standard quantum limit). The experimentally measured improvement is $2.24 \pm 0.14$

The general form of supersymmetric solutions of N=(1,0) U(1) and SU(2) gauged supergravities in six dimensions

We obtain necessary and sufficient conditions for a supersymmetric field configuration in the N=(1,0) U(1) or SU(2) gauged supergravities in six dimensions, and impose the field equations on this general ansatz. It is found that any supersymmetric solution is associated to an $SU(2)\ltimes \mathbb{R}^4$ structure. The structure is characterized by a null Killing vector which induces a natural 2+4 split of the six dimensional spacetime. A suitable combination of the field equations implies that the scalar curvature of the four dimensional Riemannian part, referred to as the base, obeys a second order differential equation. Bosonic fluxes introduce torsion terms that deform the $SU(2)\ltimes\mathbb{R}^4$ structure away from a covariantly constant one. The most general structure can be classified in terms of its intrinsic torsion. For a large class of solutions the gauge field strengths admit a simple geometrical interpretation: in the U(1) theory the base is K\"{a}hler, and the gauge field strength is the Ricci form; in the SU(2) theory, the gauge field strengths are identified with the curvatures of the left hand spin bundle of the base. We employ our general ansatz to construct new supersymmetric solutions; we show that the U(1) theory admits a symmetric Cahen-Wallach$_4\times S^2$ solution together with a compactifying pp-wave. The SU(2) theory admits a black string, whose near horizon limit is $AdS_3\times S_3$. We also obtain the Yang-Mills analogue of the Salam-Sezgin solution of the U(1) theory, namely $R^{1,2}\times S^3$, where the $S^3$ is supported by a sphaleron. Finally we obtain the additional constraints implied by enhanced supersymmetry, and discuss Penrose limits in the theories.Comment: 1+29 pages, late

On the mass of a Kerr-anti-de Sitter spacetime in D dimensions

We show how to compute the mass of a Kerr-anti-de Sitter spacetime with respect to the anti-de Sitter background in any dimension, using a superpotential which has been derived from standard Noether identities. The calculation takes no account of the source of the curvature and confirms results obtained for black holes via the first law of thermodynamics.Comment: minor changes; accepted by CQ