X-ray Sources and their Optical Counterparts in the Globular Cluster M4

We report on the Chandra X-ray Observatory ACIS-S3 imaging observation of the Galactic globular cluster M4 (NGC 6121). We detect 12 X-ray sources inside the core and 19 more within the cluster half-mass radius. The limiting luminosity of this observation is Lx~10e29 erg/sec for sources associated with the cluster, the deepest X-ray observation of a globular cluster to date. We identify 6 X-ray sources with known objects and use ROSAT observations to show that the brightest X-ray source is variable. Archival data from the Hubble Space Telescope allow us to identify optical counterparts to 16 X-ray sources. Based on the X-ray and optical properties of the identifications and the information from the literature, we classify two (possibly three) sources as cataclysmic variables, one X-ray source as a millisecond pulsar and 12 sources as chromospherically active binaries. Comparison of M4 with 47 Tuc and NGC 6397 suggests a scaling of the number of active binaries in these clusters with the cluster (core) mass.Comment: 11 pages, 6 figures, accepted for publication in ApJ. Figure 1 and 5 are of reduced qualit

Low Luminosity X-ray Sources And Their Optical Counterparts In The Globular Cluster NGC 362: The Chandra/HST Perspective

Item does not contain fulltextAAS Meeting #213, 4 januari 200

IR observations of the double quasar 0957 + 561 A, B and the intervening galaxy

The properties of the remarkable double quasar 0957 + 561 were first described by Walsh et al. Recently Young et al. have described CCD observations of a distant galaxy associated with the quasar pair, and have identified this galaxy as a gravitational lens forming a double image of a single quasar. We report here 1.2–2.2-µm observations of the system that support the conclusion that the twin quasars are a pair of images of a single object; the quasar has an energy distribution that is unusual. The intervening galaxy is shown to be highly luminous with a bolometric luminosity of about 2 × 10^(11) L

The association between HTR2C gene polymorphisms and the metabolic syndrome in patients with schizophrenia.

Contains fulltext : 53650.pdf (publisher's version ) (Closed access)The use of antipsychotics is associated with metabolic side effects, which put patients with schizophrenia or related disorders at risk for cardiovascular morbidity. The high interindividual variability in antipsychotic-induced metabolic abnormalities suggests that genetic makeup is a possible determinant. In this cross-sectional study, we investigated whether genotypes of the HTR2C receptor are associated with the metabolic syndrome in patients using antipsychotics. Patients were identified from a schizophrenia disease management program. In this program, patients' blood pressure, triglycerides, high-density lipoprotein-cholesterol, and waist circumference are measured regularly during follow-up. The primary end point of our study was the prevalence of the metabolic syndrome as classified by a modified version of the National Cholesterol Education Program's Adult Treatment Panel III. Primary determinants were polymorphisms in the HTR2C receptor gene (HTR2C:c.1-142948[GT]n, rs3813928 [-997 G/A], rs3813929 [-759 C/T], rs518147 [-697 G/C], and rs1414334 [C > G]). The included patients (n = 112) mainly (>80%) used atypical antipsychotics (clozapine, olanzapine, and risperidone). Carriership of the variant alleles of the HTR2C polymorphisms rs518147, rs1414334, and HTR2C:c.1-142948(GT)n was associated with an increased risk of the metabolic syndrome (adjusted odds ratio [OR], 2.62 [95% confidence interval {CI}, 1.00-6.85]; OR, 4.09 [95% CI, 1.41-11.89]; and OR, 3.12 [95% CI, 1.13-8.16]), respectively. Our findings suggest that HTR2C genotypes are associated with antincreased risk of metabolic syndrome in patients taking antipsychotics