956 research outputs found
Structure of a large social network
We study a social network consisting of over individuals, with a
degree distribution exhibiting two power scaling regimes separated by a
critical degree , and a power law relation between degree and
local clustering. We introduce a growing random model based on a local
interaction mechanism that reproduces all of the observed scaling features and
their exponents. Our results lend strong support to the idea that several very
different networks are simultenously present in the human social network, and
these need to be taken into account for successful modeling.Comment: 5 pages, 5 figure
The physics of spreading processes in multilayer networks
The study of networks plays a crucial role in investigating the structure,
dynamics, and function of a wide variety of complex systems in myriad
disciplines. Despite the success of traditional network analysis, standard
networks provide a limited representation of complex systems, which often
include different types of relationships (i.e., "multiplexity") among their
constituent components and/or multiple interacting subsystems. Such structural
complexity has a significant effect on both dynamics and function. Throwing
away or aggregating available structural information can generate misleading
results and be a major obstacle towards attempts to understand complex systems.
The recent "multilayer" approach for modeling networked systems explicitly
allows the incorporation of multiplexity and other features of realistic
systems. On one hand, it allows one to couple different structural
relationships by encoding them in a convenient mathematical object. On the
other hand, it also allows one to couple different dynamical processes on top
of such interconnected structures. The resulting framework plays a crucial role
in helping achieve a thorough, accurate understanding of complex systems. The
study of multilayer networks has also revealed new physical phenomena that
remain hidden when using ordinary graphs, the traditional network
representation. Here we survey progress towards attaining a deeper
understanding of spreading processes on multilayer networks, and we highlight
some of the physical phenomena related to spreading processes that emerge from
multilayer structure.Comment: 25 pages, 4 figure
The need to promote behaviour change at the cultural level: one factor explaining the limited impact of the MEMA kwa Vijana adolescent sexual health intervention in rural Tanzania. A process evaluation
Background - Few of the many behavioral sexual health interventions in Africa have been rigorously evaluated. Where biological outcomes have been measured, improvements have rarely been found. One of the most rigorous trials was of the multi-component MEMA kwa Vijana adolescent sexual health programme, which showed improvements in knowledge and reported attitudes and behaviour, but none in biological outcomes. This paper attempts to explain these outcomes by reviewing the process evaluation findings, particularly in terms of contextual factors.
Methods - A large-scale, primarily qualitative process evaluation based mainly on participant observation identified the principal contextual barriers and facilitators of behavioural change.
Results - The contextual barriers involved four interrelated socio-structural factors: culture (i.e. shared practices and systems of belief), economic circumstances, social status, and gender. At an individual level they appeared to operate through the constructs of the theories underlying MEMA kwa Vijana - Social Cognitive Theory and the Theory of Reasoned Action – but the intervention was unable to substantially modify these individual-level constructs, apart from knowledge.
Conclusion - The process evaluation suggests that one important reason for this failure is that the intervention did not operate sufficiently at a structural level, particularly in regard to culture. Recently most structural interventions have focused on gender or/and economics. Complementing these with a cultural approach could address the belief systems that justify and perpetuate gender and economic inequalities, as well as other barriers to behaviour change
A Biased Review of Sociophysics
Various aspects of recent sociophysics research are shortly reviewed:
Schelling model as an example for lack of interdisciplinary cooperation,
opinion dynamics, combat, and citation statistics as an example for strong
interdisciplinarity.Comment: 16 pages for J. Stat. Phys. including 2 figures and numerous
reference
The Interface Region Imaging Spectrograph (IRIS)
The Interface Region Imaging Spectrograph (IRIS) small explorer spacecraft
provides simultaneous spectra and images of the photosphere, chromosphere,
transition region, and corona with 0.33-0.4 arcsec spatial resolution, 2 s
temporal resolution and 1 km/s velocity resolution over a field-of-view of up
to 175 arcsec x 175 arcsec. IRIS was launched into a Sun-synchronous orbit on
27 June 2013 using a Pegasus-XL rocket and consists of a 19-cm UV telescope
that feeds a slit-based dual-bandpass imaging spectrograph. IRIS obtains
spectra in passbands from 1332-1358, 1389-1407 and 2783-2834 Angstrom including
bright spectral lines formed in the chromosphere (Mg II h 2803 Angstrom and Mg
II k 2796 Angstrom) and transition region (C II 1334/1335 Angstrom and Si IV
1394/1403 Angstrom). Slit-jaw images in four different passbands (C II 1330, Si
IV 1400, Mg II k 2796 and Mg II wing 2830 Angstrom) can be taken simultaneously
with spectral rasters that sample regions up to 130 arcsec x 175 arcsec at a
variety of spatial samplings (from 0.33 arcsec and up). IRIS is sensitive to
emission from plasma at temperatures between 5000 K and 10 MK and will advance
our understanding of the flow of mass and energy through an interface region,
formed by the chromosphere and transition region, between the photosphere and
corona. This highly structured and dynamic region not only acts as the conduit
of all mass and energy feeding into the corona and solar wind, it also requires
an order of magnitude more energy to heat than the corona and solar wind
combined. The IRIS investigation includes a strong numerical modeling component
based on advanced radiative-MHD codes to facilitate interpretation of
observations of this complex region. Approximately eight Gbytes of data (after
compression) are acquired by IRIS each day and made available for unrestricted
use within a few days of the observation.Comment: 53 pages, 15 figure
Versatile Coordination of Cyclopentadienyl-Arene Ligands and Its Role in Titanium-Catalyzed Ethylene Trimerization
Cationic titanium(IV) complexes with ansa-(η5-cyclopentadienyl,η6-arene) ligands were synthesized and characterized by X-ray crystallography. The strength of the metal-arene interaction in these systems was studied by variable-temperature NMR spectroscopy. Complexes with a C1 bridge between the cyclopentadienyl and arene moieties feature hemilabile coordination behavior of the ligand and consequently are active ethylene trimerization catalysts. Reaction of the titanium(IV) dimethyl cations with CO results in conversion to the analogous cationic titanium(II) dicarbonyl species. Metal-to-ligand backdonation in these formally low-valent complexes gives rise to a strongly bonded, partially reduced arene moiety. In contrast to the η6-arene coordination mode observed for titanium, the more electron-rich vanadium(V) cations [cyclopentadienyl-arene]V(NiPr2)(NC6H4-4-Me)+ feature η1-arene binding, as determined by a crystallographic study. The three different metal-arene coordination modes that we experimentally observed model intermediates in the cycle for titanium-catalyzed ethylene trimerization. The nature of the metal-arene interaction in these systems was studied by DFT calculations.
Mixing patterns and the spread of close-contact infectious diseases
Surprisingly little is known regarding the human mixing patterns relevant to the spread of close-contact infections, such as measles, influenza and meningococcal disease. This study aims to estimate the number of partnerships that individuals make, their stability and the degree to which mixing is assortative with respect to age. We defined four levels of putative at-risk events from casual (physical contact without conversation) to intimate (contact of a sexual nature), and asked university student volunteers to record details on those they contacted at these levels on three separate days. We found that intimate contacts are stable over short time periods whereas there was no evidence of repeat casual contacts with the same individuals. The contacts were increasingly assortative as intimacy increased. Such information will aid the development and parameterisation of models of close contact diseases, and may have direct use in outbreak investigations
Occupational exposure to gases/fumes and mineral dust affect DNA methylation levels of genes regulating expression
Many workers are daily exposed to occupational agents like gases/fumes, mineral dust or biological dust, which could induce adverse health effects. Epigenetic mechanisms, such as DNA methylation, have been suggested to play a role. We therefore aimed to identify differentially methylated regions (DMRs) upon occupational exposures in never-smokers and investigated if these DMRs associated with gene expression levels. To determine the effects of occupational exposures independent of smoking, 903 never-smokers of the LifeLines cohort study were included. We performed three genome-wide methylation analyses (Illumina 450 K), one per occupational exposure being gases/fumes, mineral dust and biological dust, using robust linear regression adjusted for appropriate confounders. DMRs were identified using comb-p in Python. Results were validated in the Rotterdam Study (233 never-smokers) and methylation-expression associations were assessed using Biobank-based Integrative Omics Study data (n = 2802). Of the total 21 significant DMRs, 14 DMRs were associated with gases/fumes and 7 with mineral dust. Three of these DMRs were associated with both exposures (RPLP1 and LINC02169 (2x)) and 11 DMRs were located within transcript start sites of gene expression regulating genes. We replicated two DMRs with gases/fumes (VTRNA2-1 and GNAS) and one with mineral dust (CCDC144NL). In addition, nine gases/fumes DMRs and six mineral dust DMRs significantly associated with gene expression levels. Our data suggest that occupational exposures may induce differential methylation of gene expression regulating genes and thereby may induce adverse health effects. Given the millions of workers that are exposed daily to occupational exposures, further studies on this epigenetic mechanism and health outcomes are warranted
E-readers and the death of the book: or, new media and the myth of the disappearing medium
The recent emergence of e-readers and e-books has b
rought the death of the book to the centre of
current debates on new media. In this article, we a
nalyse alternative narratives that surround the
possibility of the disappearance of print books, do
minated by fetishism, fears about the end of
humanism, and ideas of techno-fundamentalist progre
ss. We argue that, in order to comprehend
such narratives, we need to inscribe them in the br
oader history of media. The emergence of new
media, in fact, has often been accompanied by narra
tives about the possible disappearance of
older media: the introduction of television, for in
stance, inspired claims about the forthcoming
death of film and radio. As a recurrent narrative s
haping the reception of media innovation, the
myth of the disappearing medium helps us to make se
nse of the transformations that media
change provokes in our everyday life
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