Profile of susceptibility in vitro of Trichosporon asahii and Trichosporon inkin strains against cyclic imides

In vitro susceptibility testing of Trichosporon asahii (13 strains) and T. inkin (13 strains) against cyclic imides (succinimides, naphtalimides and maleimides) in concentrations of 200 to 6,25 µg/mL was performed according to the diffusion agar method. By the results obtained, the antifungal activity of the cyclic imides: 3,4-dichloro-N-phenyl-maleimide; 3,4-dichloro-N-phenyl-ethyl-maleimide and 3,4-dichloro-N-phenyl-propyl-maleimide (50 µg/mL) over T. asahii and T. inkin was important and it may be helpful in showing perspectives in a search for new antimicotic products.O perfil de sensibilidade in vitro de Trichosporon asahii (13 cepas) e T. inkin (13 cepas) frente a imidas cíclicas (naftalimidas, succinimidas e maleimidas) nas concentrações de 6,25 a 200 µg/mL foi realizado pelo método de difusão em agar. Pelos resultados obtidos, a atividade antifúngica das imidas cíclicas: 3,4-dicloro-N-fenil-maleimida; 3,4-dicloro-N-fenil-etil-maleimida e 3,4-dicloro-N-fenil-propil-maleimida (50 µg/mL) sobre T. asahii e T. inkin foi importante e pode abrir perspectivas na busca de novos produtos antimicóticos

Clinical and mycological study of scalp white piedra in the State of Paraíba, Brazil

White piedra is a superficial mycoses characterized by nodules on the hair shaft, caused by the basidiomycetous yeasts. In the present study, clinical and mycological findings of scalp white piedra caused by Trichosporon spp. are related. Twenty three cases of scalp white piedra were observed with a high incidence in women (87%) and preschool children from 2 to 6 (74%) years old. These groups presented a relationship of dependence with this infection. Despite the low socio-economic status, poor standards of hygiene, (48% of the patients) as well as the fact that 30.4% of the children shared the same nursery, these factors were not significant for the transmission of the mycosis. These were the first reports of scalp white piedra in João Pessoa city, Paraíba, Brazil