Marketing competition on a new product introduction - a structural analysis using systems thinking

Launching a new product on the market is a strategic activity that needs specific investments and a specific organisation. There are multiple factors that determine the success of a new product on the market but their direct effects are not often very well observable (marketing for example). With this study, we analysed the systemic structure underlying the dynamics related to the introduction of a new product on the market. In particular, we built a qualitative model based on the systems thinking methodology of causal-loop diagrams (CLDs), starting from the main structure and assumptions of the well-known Bass model. The model provides a systemic perspective on the interdependencies among various aspects that interact in important organisational areas. The presented causal-loop diagram tries to describe the systems structure which is intrinsic to the introduction and diffusion of a new product on the market, and how ultimately the related dynamics could be manage

Training in systems thinking and system dynamics as an effective way to tackle complexity in the management of organisations

The biggest challenge for today’s organisations is to address the growing complexity of their internal and external environment while gaining a competitive advantage. To do this, the leaders of the organisations must be able to understand this complexity through the knowledge of the environment and the implementation of a governance system based on a decision-making process that considers the enormous amount of data available. Such data must lead to the availability of information that guides the organisations themselves in the learning process. Sustainable development requires organisations to rethink their goals and/or business models, with effects on their day-to-day activities. Pursuing to become more sustainable is not only a need for marketing reasons but also an opportunity for growth and alignment with emerging trends. However, managing the complexity of sustainability is not straightforward and requires cognitive and practical tools that are able to capture and jointly consider a wide variety of interrelated factors. Modelling the processes that characterise complex organisations is not an easy task. The aim of this contribution is thus to identify a methodology that helps managers in tackling the challenges that organisations have to adopt when faced with a growing complexity of their internal and external environment, and that might help managers at all levels when analysing various business and management situations, to account for non-linearities, path-dependency and time lags, and that may allow also for organisational and social learning. The study shows how the System Dynamics approach, identified as a methodology for modelling and simulation, is able to lead to the development of effective skills and strategic learning for the management of organisations and hence support the dynamic evaluations of strategies and performance. The System Thinking and System Dynamics approach may prove a useful combined tool for next-generation decision-makers, but this approach needs to be understood and learned in order to develop the necessary skills. In particular, this study will show the results of a test conducted with the collaboration of undergraduate university students, who have attended a course about System Dynamics, in order to test their ability to understand the dynamics underlying counterintuitive system behaviour

A systemic perspective on racism in football: the experience of the BRISWA project

The objective of this paper is to present the process for the development of a causal loop diagram that captures the relevant aspects of racism in football, through a holistic, top-down approach. To do so, a series of workshops/sessions has been organised with experts in the field and with the purpose of designing a tool that could be used to get better insights into how racism in football emerges and where are the potential areas where policymakers could use as leverage for effective counter-measures. The diagram demonstrated the multi-faceted nature of racism, the phenomena that might give rise to it and the elements that could serve as leverage in potential counter-measures. Some of the most interesting results include the following: the power structures of society and football should adapt to represent the actual demographic make-up of each country. Furthermore, policymakers should involve media more directly in every attempt to fight racism. Finally, racism in football is a mirror of racism in society. Hence, any attempt to combat racism in football should be interlinked with corresponding efforts to fight discrimination in society

Use of System Dynamics Models as Part of a Game-based, Urban Sustainability Course for Students in Higher Education (SUSTAIN Project)

The difficulty with sustainability arises from its abstract nature and the fact that these problems have long term horizons. The objective of the SUSTAIN course is to promote sustainability literacy among students of higher education through an innovative and student-centered education that makes use of system dynamics (SD) models embedded in game-based learning. In this project, as part of the SUSTAIN course, we try to develop small illustrative SD simulation models that will allow for experimentation in a consequence-free environment. These simulation models will then be translated to game elements, mechanics and potential playing scenarios for a table top / board game that deal with sustainability issues. The purpose of this project under development is to help students of higher education achieve competences such as the ability of constantly assessing the environment, operating and adapting to it through continuous and iterative individual process of revision from their frames of reference, and to provide the material to comprehend systemic complexity. We expect these competences to allow them to deal with complex decisions and decision making processes in their future careers in private and public organizations, and provide insights into the complexity and the effort required to achieve the Sustainable Development Goals (SDGs)

The Rural-Urban Food Systems’ Links with the Agenda 2030: From FAO Guidelines on Food Supply and Distribution Systems to a Dairy Sector Application in the Area of Bogota

What should be the policy to meet urban food needs in developing countries and those in transition? This is a key question of the Food and Agriculture Organization of the United Nations (FAO), which was posed into the “FAO’s methodological and operational guide to study and understand Food Supply and Distribution Systems (FSDS) to cities in developing countries and countries in transition” in order to face the current overwhelming increase of urban population and the increasing urbanization pressures on food systems. Following some previous work in the field where it was argued that clarifying the various problems and structure behind Food Supply and Distribution Systems (FSDS) in urban environments is vital to assess policies that aim at meeting urban food needs, the purpose of this paper is to show that the methodological approach known as system dynamics modeling and simulation can lead, in terms of knowledge and/or theoretical contribution, to the unfolding of complexity in this area of research as well as bring into the analysis the relationships across a few goals of the Agenda 2030. As an additional result, we show how the developed model can be applied (case of the production of milk for consumption in the city of Bogota, Colombia) to analyze the dynamics of food supply and distribution systems in urban environments

Kinematic and stellar population properties of the counter-rotating components in the S0 galaxy NGC 1366

Context. Many disk galaxies host two extended stellar components that rotate in opposite directions. The analysis of the stellar populations of the counter-rotating components provides constraints on the environmental and internal processes that drive their formation. Aims. The S0 NGC 1366 in the Fornax cluster is known to host a stellar component that is kinematically decoupled from the main body of the galaxy. Here we successfully separated the two counter-rotating stellar components to independently measure the kinematics and properties of their stellar populations. Methods. We performed a spectroscopic decomposition of the spectrum obtained along the galaxy major axis and separated the relative contribution of the two counter-rotating stellar components and of the ionized-gas component. We measured the line-strength indices of the two counter-rotating stellar components and modeled each of them with single stellar population models that account for the \u3b1/Fe overabundance. Results. We found that the counter-rotating stellar component is younger, has nearly the same metallicity, and is less \u3b1/Fe enhanced than the corotating component. Unlike most of the counter-rotating galaxies, the ionized gas detected in NGC 1366 is neither associated with the counter-rotating stellar component nor with the main galaxy body. On the contrary, it has a disordered distribution and a disturbed kinematics with multiple velocity components observed along the minor axis of the galaxy. Conclusions. The different properties of the counter-rotating stellar components and the kinematic peculiarities of the ionized gas suggest that NGC 1366 is at an intermediate stage of the acquisition process, building the counter-rotating components with some gas clouds still falling onto the galaxy. \ua9 ESO 2017

An innovative game-based approach for teaching urban sustainability

This paper is based on SUSTAIN, an ERASMUS+ project with an innovative perspective on urban transportation, and its target is to promote the importance of sustainability on the everyday problem of urban transportation among the students of higher education (and not only), who are the policy makers of tomorrow. In order to achieve its goals, the research team is currently developing a course that will be based on an interactive serious board game with an analytical style of education. SUSTAIN's purpose is to create a game that will allow students to learn about transportation sustainability and societal metabolism through playing. The project partners develop small and illustrative simulation models, which will make the definitions more concrete and allow students to experiment largely in a consequence-free environment. The simulation models can be used to identify scenario exemplars on how we can achieve sustainable urban transportation and consequently a balanced societal metabolism, while on the same time taking into account formal decision making processes. In this paper, we are going to explain a Stocks & Flows Diagram for the above mentioned model, with a system dynamics approac

Off–label long acting injectable antipsychotics in real–world clinical practice: a cross-sectional analysis of prescriptive patterns from the STAR Network DEPOT study

Introduction: Information on the off–label use of Long–Acting Injectable (LAI) antipsychotics in the real world is lacking. In this study, we aimed to identify the sociodemographic and clinical features of patients treated with on– vs off–label LAIs and predictors of off–label First– or Second–Generation Antipsychotic (FGA vs. SGA) LAI choice in everyday clinical practice. Method: In a naturalistic national cohort of 449 patients who initiated LAI treatment in the STAR Network Depot Study, two groups were identified based on off– or on–label prescriptions. A multivariate logistic regression analysis was used to test several clinically relevant variables and identify those associated with the choice of FGA vs SGA prescription in the off–label group. Results: SGA LAIs were more commonly prescribed in everyday practice, without significant differences in their on– and off–label use. Approximately 1 in 4 patients received an off–label prescription. In the off–label group, the most frequent diagnoses were bipolar disorder (67.5%) or any personality disorder (23.7%). FGA vs SGA LAI choice was significantly associated with BPRS thought disorder (OR = 1.22, CI95% 1.04 to 1.43, p = 0.015) and hostility/suspiciousness (OR = 0.83, CI95% 0.71 to 0.97, p = 0.017) dimensions. The likelihood of receiving an SGA LAI grew steadily with the increase of the BPRS thought disturbance score. Conversely, a preference towards prescribing an FGA was observed with higher scores at the BPRS hostility/suspiciousness subscale. Conclusion: Our study is the first to identify predictors of FGA vs SGA choice in patients treated with off–label LAI antipsychotics. Demographic characteristics, i.e. age, sex, and substance/alcohol use co–morbidities did not appear to influence the choice towards FGAs or SGAs. Despite a lack of evidence, clinicians tend to favour FGA over SGA LAIs in bipolar or personality disorder patients with relevant hostility. Further research is needed to evaluate treatment adherence and clinical effectiveness of these prescriptive patterns

Off-label long acting injectable antipsychotics in real-world clinical practice: a cross-sectional analysis of prescriptive patterns from the STAR Network DEPOT study

Introduction Information on the off-label use of Long-Acting Injectable (LAI) antipsychotics in the real world is lacking. In this study, we aimed to identify the sociodemographic and clinical features of patients treated with on- vs off-label LAIs and predictors of off-label First- or Second-Generation Antipsychotic (FGA vs. SGA) LAI choice in everyday clinical practice. Method In a naturalistic national cohort of 449 patients who initiated LAI treatment in the STAR Network Depot Study, two groups were identified based on off- or on-label prescriptions. A multivariate logistic regression analysis was used to test several clinically relevant variables and identify those associated with the choice of FGA vs SGA prescription in the off-label group. Results SGA LAIs were more commonly prescribed in everyday practice, without significant differences in their on- and off-label use. Approximately 1 in 4 patients received an off-label prescription. In the off-label group, the most frequent diagnoses were bipolar disorder (67.5%) or any personality disorder (23.7%). FGA vs SGA LAI choice was significantly associated with BPRS thought disorder (OR = 1.22, CI95% 1.04 to 1.43, p = 0.015) and hostility/suspiciousness (OR = 0.83, CI95% 0.71 to 0.97, p = 0.017) dimensions. The likelihood of receiving an SGA LAI grew steadily with the increase of the BPRS thought disturbance score. Conversely, a preference towards prescribing an FGA was observed with higher scores at the BPRS hostility/suspiciousness subscale. Conclusion Our study is the first to identify predictors of FGA vs SGA choice in patients treated with off-label LAI antipsychotics. Demographic characteristics, i.e. age, sex, and substance/alcohol use co-morbidities did not appear to influence the choice towards FGAs or SGAs. Despite a lack of evidence, clinicians tend to favour FGA over SGA LAIs in bipolar or personality disorder patients with relevant hostility. Further research is needed to evaluate treatment adherence and clinical effectiveness of these prescriptive patterns

Comparing Long-Acting Antipsychotic Discontinuation Rates Under Ordinary Clinical Circumstances: A Survival Analysis from an Observational, Pragmatic Study

Background: Recent guidelines suggested a wider use of long-acting injectable antipsychotics (LAI) than previously, but naturalistic data on the consequences of LAI use in terms of discontinuation rates and associated factors are still sparse, making it hard for clinicians to be informed on plausible treatment courses. Objective: Our objective was to assess, under real-world clinical circumstances, LAI discontinuation rates over a period of 12 months after a first prescription, reasons for discontinuation, and associated factors. Methods: The STAR Network ‘Depot Study’ was a naturalistic, multicentre, observational prospective study that enrolled subjects initiating a LAI without restrictions on diagnosis, clinical severity or setting. Participants from 32 Italian centres were assessed at baseline and at 6 and 12 months of follow-up. Psychopathology, drug attitude and treatment adherence were measured using the Brief Psychiatric Rating Scale, the Drug Attitude Inventory and the Kemp scale, respectively. Results: The study followed 394 participants for 12 months. The overall discontinuation rate at 12 months was 39.3% (95% confidence interval [CI] 34.4–44.3), with paliperidone LAI being the least discontinued LAI (33.9%; 95% CI 25.3–43.5) and olanzapine LAI the most discontinued (62.5%; 95% CI 35.4–84.8). The most frequent reason for discontinuation was onset of adverse events (32.9%; 95% CI 25.6–40.9) followed by participant refusal of the medication (20.6%; 95% CI 14.6–27.9). Medication adherence at baseline was negatively associated with discontinuation risk (hazard ratio [HR] 0.853; 95% CI 0.742–0.981; p = 0.026), whereas being prescribed olanzapine LAI was associated with increased discontinuation risk compared with being prescribed paliperidone LAI (HR 2.156; 95% CI 1.003–4.634; p = 0.049). Conclusions: Clinicians should be aware that LAI discontinuation is a frequent occurrence. LAI choice should be carefully discussed with the patient, taking into account individual characteristics and possible obstacles related to the practicalities of each formulation