Analysis of health passports students of the second course

The article analyzes the biochemical (in blood, glucose, cholesterol) and clinical (heart rate, blood pressure) indicators of the body of medical students on the basis of 70 passports of health. Self-assessment of physical activity, eating behavior carried out by anonymous questioning 120 respondents. All studies were conducted with the voluntary consent of the respondents. Students prefer baking, "snacking". The deviation of body mass index above the standard value was found in 14%, among them in 43% - primary obesity (6% of the total number of patients). The method of paired correlations revealed a high correlation between the level of cholesterol and the systolic component of blood pressure.В статье проведен анализ биохимических (глюкоза, холестерин крови) и клинических (частота сердечных сокращений, артериальное давление) показателей организма студентов-медиков на основе 70 сведений паспортов здоровья. Самооценки физической активности, пищевого поведения осуществлены путем анонимного анкетирования 120 респондентов. Все исследования проведены при добровольном согласии анкетированных. Студенты предпочитают выпечку, «перекусы». Отклонение индекса массы тела выше стандартной величины обнаружено у 14%, среди них у 43% — первичное ожирение (6% об общего числа обследованных). Метод парных корреляций выявил высокую связь между уровнем холестерина и систолической составляющей артериального давления

Selection of parameters of machines for collection of logging waste

Abstract The article presents a methodology for a reasonable choice of parameters of a machine for collecting of logging waste, which allows to determine the possibility of the machine’s movement depending on various design parameters and natural-production factors when performing technological operations based on an assessment of the traction and coupling properties of the base chassis. A relationship has been established to determine the resistance force to dragging of logging waste, which takes into account the taxation characteristics of the plantation (liquid stock, species composition and density of wood), the parameters of technological equipment (its width) and the peculiarities of the location of the shafts of logging waste through the average distance of passes. The results of determining the resistance force of overcoming a stump with a tooth of technological equipment of a rake type are also given. The proposed nomograms allow, based on the specified operating conditions, to determine the total force of resistance to movement from technological equipment and branches. From this value, using the graphical-analytical method, based on the type of soil, the considered layout of the base chassis and the expected speed of operations, the minimum required engine power, tangential force thrust and weight of the base chassis are established. Based on the results obtained, recommendations are given on the use of various types of base chassis, depending on the type of soil.</jats:p

Edoxaban versus warfarin in patients with atrial fibrillation

Contains fulltext : 125374.pdf (publisher's version ) (Open Access)BACKGROUND: Edoxaban is a direct oral factor Xa inhibitor with proven antithrombotic effects. The long-term efficacy and safety of edoxaban as compared with warfarin in patients with atrial fibrillation is not known. METHODS: We conducted a randomized, double-blind, double-dummy trial comparing two once-daily regimens of edoxaban with warfarin in 21,105 patients with moderate-to-high-risk atrial fibrillation (median follow-up, 2.8 years). The primary efficacy end point was stroke or systemic embolism. Each edoxaban regimen was tested for noninferiority to warfarin during the treatment period. The principal safety end point was major bleeding. RESULTS: The annualized rate of the primary end point during treatment was 1.50% with warfarin (median time in the therapeutic range, 68.4%), as compared with 1.18% with high-dose edoxaban (hazard ratio, 0.79; 97.5% confidence interval [CI], 0.63 to 0.99; P<0.001 for noninferiority) and 1.61% with low-dose edoxaban (hazard ratio, 1.07; 97.5% CI, 0.87 to 1.31; P=0.005 for noninferiority). In the intention-to-treat analysis, there was a trend favoring high-dose edoxaban versus warfarin (hazard ratio, 0.87; 97.5% CI, 0.73 to 1.04; P=0.08) and an unfavorable trend with low-dose edoxaban versus warfarin (hazard ratio, 1.13; 97.5% CI, 0.96 to 1.34; P=0.10). The annualized rate of major bleeding was 3.43% with warfarin versus 2.75% with high-dose edoxaban (hazard ratio, 0.80; 95% CI, 0.71 to 0.91; P<0.001) and 1.61% with low-dose edoxaban (hazard ratio, 0.47; 95% CI, 0.41 to 0.55; P<0.001). The corresponding annualized rates of death from cardiovascular causes were 3.17% versus 2.74% (hazard ratio, 0.86; 95% CI, 0.77 to 0.97; P=0.01), and 2.71% (hazard ratio, 0.85; 95% CI, 0.76 to 0.96; P=0.008), and the corresponding rates of the key secondary end point (a composite of stroke, systemic embolism, or death from cardiovascular causes) were 4.43% versus 3.85% (hazard ratio, 0.87; 95% CI, 0.78 to 0.96; P=0.005), and 4.23% (hazard ratio, 0.95; 95% CI, 0.86 to 1.05; P=0.32). CONCLUSIONS: Both once-daily regimens of edoxaban were noninferior to warfarin with respect to the prevention of stroke or systemic embolism and were associated with significantly lower rates of bleeding and death from cardiovascular causes. (Funded by Daiichi Sankyo Pharma Development; ENGAGE AF-TIMI 48 ClinicalTrials.gov number, NCT00781391.)