Fertimetro, a Principle and Device to Measure Soil Nutrient Availability for Plants by Microbial Degradation Rates on Differently-Spiked Buried Threads

A novel patented method (PCT/IB2012/001157: Squartini, Concheri, Tiozzo, University of Padova) and the corresponding application devices, suitable to measure soil fertility, are presented. The availability or deficiency of specific nutrients for crops is assessed by monitoring the kinetics of progressive weakening of cotton or silk threads due to in situ microbial activity. The method is based on a nutrient-primed incremented substrate degradation principle. Threads are buried as is or pre-impregnated with N or P solutions, and the acceleration of the degradation rate for the N-supplemented or P-supplemented thread, in comparison to the untreated thread, is proportional to the lack of the corresponding nutrient in that soil. Tests were validated on corn crops in plots receiving increasing fertilizer rates in a historical rotation that has been established since 1962. The measurement carried out in May significantly correlated with the subsequent crop yields recorded in October. The analysis allows an early, inexpensive, fast, and reproducible self-assessment at field level to improve fertilization rates. The device is envisaged as a user-friendly tool for agronomy, horticulture, and any environmental applications where organic matter cycling, soil quality, and specific nutrients excess or deficiency are critical considerations

A System For Visual Role-Based Policy Modelling

The definition of security policies in information systems and programming applications is often accomplished through traditional low level languages that are difficult to use. This is a remarkable drawback if we consider that security policies are often specified and maintained by top level enterprise managers who would probably prefer to use simplified, metaphor oriented policy management tools. To support all the different kinds of users we propose a suite of visual languages to specify access and security policies according to the role based access control (RBAC) model. Moreover, a system implementing the proposed visual languages is proposed. The system provides a set of tools to enable a user to visually edit security policies and to successively translate them into (eXtensible Access Control Markup Language) code, which can be managed by a Policy Based Management System supporting such policy language. The system and the visual approach have been assessed by means of usability studies and of several case studies. The one presented in this paper regards the configuration of access policies for a multimedia content management platform providing video streaming services also accessible through mobile devices

Treatment-resistant to antipsychotics. A resistance to everything? Psychotherapy in treatment-resistant schizophrenia and nonaffective psychosis. A 25-year systematic review and exploratory meta-analysis

Background: Roughly 30% of schizophrenia patients fail to respond to at least two antipsychotic trials. Psychosis has been traditionally considered to be poorly sensitive to psychotherapy. Nevertheless, there is increasing evidence that psychological interventions could be considered in treatment-resistant psychosis (TRP). Despite the relevance of the issue and the emerging neurobiological underpinnings, no systematic reviews have been published. Here, we show a systematic review of psychotherapy interventions in TRP patients of the last 25 years. Methods: The MEDLINE/PubMed, ISI WEB of Knowledge, and Scopus databases were inquired from January 1, 1993, to August 1, 2018, for reports documenting augmentation or substitution with psychotherapy for treatment-resistant schizophrenia (TRS) and TRP patients. Quantitative data fetched by Randomized Controlled Trials (RCTs) were pooled for explorative meta-analysis. Results: Forty-two articles have been found. Cognitive behavioral therapy (CBT) was the most frequently recommended psychotherapy intervention for TRS (studies, n = 32, 76.2%), showing efficacy for general psychopathology and positive symptoms as documented by most of the studies, but with uncertain efficacy on negative symptoms. Other interventions showed similar results. The usefulness of group therapy was supported by the obtained evidence. Few studies focused on negative symptoms. Promising results were also reported for resistant early psychosis. Limitations: Measurement and publication bias due to the intrinsic limitations of the appraised original studies. Conclusions: CBT, psychosocial intervention, supportive counseling, psychodynamic psychotherapy, and other psychological interventions can be recommended for clinical practice. More studies are needed, especially for non-CBT interventions and for all psychotherapies on negative symptoms

Modeling Interference for the Coexistence of 6G Networks and Passive Sensing Systems

Future wireless networks and sensing systems will benefit from access to large chunks of spectrum above 100 GHz, to achieve terabit-per-second data rates in 6th Generation (6G) cellular systems and improve accuracy and reach of Earth exploration and sensing and radio astronomy applications. These are extremely sensitive to interference from artificial signals, thus the spectrum above 100 GHz features several bands which are protected from active transmissions under current spectrum regulations. To provide more agile access to the spectrum for both services, active and passive users will have to coexist without harming passive sensing operations. In this paper, we provide the first, fundamental analysis of Radio Frequency Interference (RFI) that large-scale terrestrial deployments introduce in different satellite sensing systems now orbiting the Earth. We develop a geometry-based analysis and extend it into a data-driven model which accounts for realistic propagation, building obstruction, ground reflection, for network topology with up to $10^5$ nodes in more than $85$ km$^2$. We show that the presence of harmful RFI depends on several factors, including network load, density and topology, satellite orientation, and building density. The results and methodology provide the foundation for the development of coexistence solutions and spectrum policy towards 6G

Toward Open Integrated Access and Backhaul with O-RAN

Millimeter wave (mmWave) communications has been recently standardized for use in the fifth generation (5G) of cellular networks, fulfilling the promise of multi-gigabit mobile throughput of current and future mobile radio network generations. In this context, the network densification required to overcome the difficult mmWave propagation will result in increased deployment costs. Integrated Access and Backhaul (IAB) has been proposed as an effective mean of reducing densification costs by deploying a wireless mesh network of base stations, where backhaul and access transmissions share the same radio technology. However, IAB requires sophisticated control mechanisms to operate efficiently and address the increased complexity. The Open Radio Access Network (RAN) paradigm represents the ideal enabler of RAN intelligent control, but its current specifications are not compatible with IAB. In this work, we discuss the challenges of integrating IAB into the Open RAN ecosystem, detailing the required architectural extensions that will enable dynamic control of 5G IAB networks. We implement the proposed integrated architecture into the first publiclyavailable Open-RAN-enabled experimental framework, which allows prototyping and testing Open-RAN-based solutions over end-to-end 5G IAB networks. Finally, we validate the framework with both ideal and realistic deployment scenarios exploiting the large-scale testing capabilities of publicly available experimental platforms

Cognitive stimulation induces differential gene expression in octopus vulgaris: The key role of protocadherins

Octopuses are unique invertebrates, with sophisticated and flexible behaviors controlled by a high degree of brain plasticity, learning, and memory. Moreover, in Octopus vulgaris, it has been demonstrated that animals housed in an enriched environment show adult neurogenesis in specific brain areas. Firstly, we evaluated the optimal acclimatization period needed for an O. vulgaris before starting a cognitive stimulation experiment. Subsequently, we analyzed differential gene expression in specific brain areas in adult animals kept in tested (enriched environment), wild (naturally enriched environment), and control conditions (unenriched environment). We selected and sequenced three protocadherin genes (PCDHs) involved in the development and maintenance of the nervous system; three Pax genes that control cell specification and tissue differentiation; the Elav gene, an earliest marker for neural cells; and the Zic1 gene, involved in early neural formation in the brain. In this paper, we evaluated gene expression levels in O. vulgaris under different cognitive stimulations. Our data shows that Oct-PCDHs genes are upregulated in the learning and lower motor centers in the brain of both tested and wild animals (higher in the latter). Combining these results with our previous studies on O. vulgaris neurogenesis, we proposed that PCDH genes may be involved in adult neurogenesis processes, and related with their cognitive abilities

The blue lizard spandrel and the island syndrome

<p>Abstract</p> <p>Background</p> <p>Many small vertebrates on islands grow larger, mature later, lay smaller clutches/litters, and are less sexually dimorphic and aggressive than their mainland relatives. This set of observations is referred to as the 'Island Syndrome'. The syndrome is linked to high population density on islands. We predicted that when population density is low and/or fluctuating insular vertebrates may evolve correlated trait shifts running opposite to the Island Syndrome, which we collectively refer to as the 'reversed island syndrome' (RIS) hypothesis. On the proximate level, we hypothesized that RIS is caused by increased activity levels in melanocortin receptors. Melanocortins are postranslational products of the proopiomelanocortin gene, which controls pleiotropically pigmentation, aggressiveness, sexual activity, and food intake in vertebrates.</p> <p>Results</p> <p>We tested the RIS hypothesis performing a number of behavioral, genetic, and ontogenetic tests on a blue colored insular variant of the Italian Wall lizard <it>Podarcis sicula</it>, living on a small island off the Southern Italian coast. The population density of this blue-colored variant was generally low and highly fluctuating from one year to the next.</p> <p>In keeping with our predictions, insular lizards were more aggressive and sexually dimorphic than their mainland relatives. Insular males had wide, peramorphic heads. The growth rate of insular females was slower than growth rates of mainland individuals of both sexes, and of insular males. Consequently, size and shape dimorphism are higher on the Island. As predicted, melanocortin receptors were much more active in individuals of the insular population. Insular lizards have a higher food intake rate than mainland individuals, which is consistent with the increased activity of melanocortin receptors. This may be adaptive in an unpredictable environment such as Licosa Island. Insular lizards of both sexes spent less time basking than their mainland relatives. We suspect this is a by-product (spandrel) of the positive selection for increased activity of melanocortins receptors.</p> <p>Conclusions</p> <p>We contend that when population density is either low or fluctuating annually as a result of environmental unpredictability, it may be advantageous to individuals to behave more aggressively, to raise their rate of food intake, and allocate more energy into reproduction.</p

The influence of salinity on the toxicity of remediated seawater

Mercury (Hg) is one of the most hazardous pollutants, due to its toxicity, biological magnification and worldwide persistence in aquatic systems. Thus, new efficient nanotechnologies (e.g. graphene oxide functionalized with polyethyleneimine (GO-PEI)) have been developed to remove this metal from the water. Aquatic environments, in particular transitional systems, are also subjected to disturbances resulting from climate change, such as salinity shifts. Salinity is one of the most relevant factors that influences the distribution and survival of aquatic species such as mussels. To our knowledge, no studies assessed the ecotoxicological impairments induced in marine organisms exposed to remediate seawater (RSW) under different salinity levels. For this, the focus of the present study was to evaluate the effects of seawater previously contaminated with Hg and remediated with GO-PEI, using the species Mytilus galloprovincialis, maintained at three different salinities (30, 20 and 40). The results obtained demonstrated similar histopathological and metabolic alterations, oxidative stress and neurotoxicity in mussels under RSW treatment at stressful salinity conditions (20 and 40) in comparison to control salinity (30). On the other hand, the present findings revealed toxicological effects including cellular damage and histopathological impairments in mussels exposed to Hg contaminated seawater in comparison to non-contaminated ones, at each salinity level. Overall, these results confirm the high efficiency of GO-PEI to sorb Hg from water with no noticeable toxic effects even under different salinities, leading to consider it a promising eco-friendly approach to remediate contaminated water

The influence of temperature increase on the toxicity of mercury remediated seawater using the nanomaterial graphene oxide on the mussel mytilus galloprovincialis

Mercury (Hg) has been increasing in waters, sediments, soils and air, as a result of natural events and anthropogenic activities. In aquatic environments, especially marine systems (estuaries and lagoons), Hg is easily bioavailable and accumulated by aquatic wildlife, namely bivalves, due to their lifestyle characteristics (sedentary and filter-feeding behavior). In recent years, different approaches have been developed with the objective of removing metal(loid)s from the water, includ-ing the employment of nanomaterials. However, coastal systems and marine organisms are not ex-clusively challenged by pollutants but also by climate changes such as progressive temperature in-crement. Therefore, the present study aimed to (i) evaluate the toxicity of remediated seawater, previously contaminated by Hg (50 mg/L) and decontaminated by the use of graphene-based nano-materials (graphene oxide (GO) functionalized with polyethyleneimine, 10 mg/L), towards the mussel Mytilus galloprovincialis; (ii) assess the influence of temperature on the toxicity of decontaminated seawater. For this, alterations observed in mussels’ metabolic capacity, oxidative and neurotoxic status, as well as histopathological injuries in gills and digestive tubules were measured. This study demonstrated that mussels exposed to Hg contaminated seawater presented higher impacts than organisms under remediated seawater. When comparing the impacts at 21 °C (present study) and 17 °C (previously published data), organisms exposed to remediated seawater at a higher temperature presented higher injuries than organisms at 17 °C. These results indicate that predicted warming conditions may negatively affect effective remediation processes, with the increasing of temperature being responsible for changes in organisms’ sensitivity to pollutants or increasing pollutants toxicity