Two-Stream Instability Model With Electrons Trapped in Quadrupoles

We formulate the theory of the two-stream instability (e-cloud instability) with electrons trapped in quadrupole magnets. We show that a linear instability theory can be sensibly formulated and analyzed. The growth rates are considerably smaller than the linear growth rates for the two-stream instability in drift spaces and are close to those actually observed

Om Enges Frugtbargjørelse ved Sænkning af deres Overflade.

Om Enges Frugtbargjørelse ved Sænkning af deres Overflade

Metamaterials: optical activity without chirality

We report that the classical phenomenon of optical activity, which is traditionally associated with chirality (helicity) of organic molecules, proteins, and inorganic structures, can be observed in artificial planar media which exhibit neither 3D nor 2D chirality. We observe the effect in the microwave and optical parts of the spectrum at oblique incidence to regular arrays of nonchiral subwavelength metamolecules in the form of strong circular dichroism and birefringence indistinguishable from those of chiral three-dimensional media

26-Desmethyl-2-methylene-22-ene-19-nor-1 alpha,25-dihydroxyvitamin D-3 compounds selectively active on intestine

Six new analogs of 2-methylene-19-nor-1 alpha,25-dihydroxyvitamin D-3, 6-7 and 8a,b-9a,b, have been synthesized. All compounds are characterized by a trans double bond located in the side chain between C-22 and C-23. While compounds 6 and 7 possess C-26 and C-27 methyls, compounds 8a,b and 9a,b lack one of these groups. A Lythgoe-based synthesis, employing the Wittig-Horner reaction was used for these preparations. Two different types of Delta E-22-25-hydroxy Grundmann's ketone, having either only one stereogenic center located at position C-20 (20 and 21), or two stereogenic centers located at 20- and 25-positions (24a,b-25a,b) were obtained by a multi-step procedure from commercial vitamin D-2. The introduction of a double bond at C-22 appeared to lower biological activity in vitro and in vivo. Further removal of a 26-methyl in these analogs had little effect on receptor binding, HL-60 differentiation and CYP24A expression but markedly diminished or eliminated in vivo activity on bone calcium mobilization while retaining activity on intestinal calcium transport. (C) 2014 Elsevier Inc. All rights reserved

2-methylene-(20S,25S)-19,27-dinor-(22E)-vitamin D analogs

This invention discloses 2-methylene-(20S,25S)-19,27-dinor-(22E)-vitamin D analogs, and specifically 2-methylene-(20S,25S)-19,27-dinor-(22E)-1.alpha.,25-dihydroxyvitamin D.sub.3, and pharmaceutical uses therefor. This compound exhibits pronounced activity in arresting the proliferation of undifferentiated cells and inducing their differentiation to the monocyte thus evidencing use as an anti-cancer agent and for the treatment of skin diseases such as psoriasis as well as skin conditions such as wrinkles, slack skin, dry skin and insufficient sebum secretion. This compound also has little, if any, calcemic activity and therefore may be used to treat autoimmune disorders or inflammatory diseases in humans as well as renal osteodystrophy. This compound may also be used for the treatment or prevention of obesity

Nonlinear Elasticity of Single Collapsed Polyelectrolytes

Nonlinear elastic responses of short and stiff polyelectrolytes are investigated by dynamic simulations on a single molecule level. When a polyelectrolyte condensate undergoes a mechanical unfolding, two types of force-extension curves, i.e., a force plateau and a stick-release pattern, are observed depending on the strength of the electrostatic interaction. We provide a physical interpretation of such force-extension behavior in terms of intramolecular structures of the condensates. We also describe a charge distribution of condensed counterions onto a highly stretched polyelectrolyte, which clarifies a formation of one-dimensional strongly correlated liquid at large Coulomb coupling regime where a stick-release pattern is observed. These findings may provide significant insights into the relationship between a molecular elasticity and a molecular mechanism of like-charge attractions observed in a wide range of charged biopolymer systems.Comment: 5pages, 5figure

Randomly addressable reconfigurable photonic metamaterials

We report on randomly addressable reconfigurable metamaterials that can be driven by thermal, Lorentz or Coulomb forces. Simultaneous spatial and temporal modulation of optical material properties enables various metadevices on demand

Экспериментальные исследования периодического способа питания забоя скважин дробью

High power diode lasers have become an established source for numerous direct applications like metal hardening and polymer welding due to their high efficiency, small size, low cost and high reliability. These laser sources are also used for efficient pumping of solid state lasers as Nd:YAG lasers. To increase the output power of diode lasers up to several kilowatts, the emitters are scaled laterally by forming a diode laser bar and vertically by forming a diode laser stack. For most applications like hardening and illumination, though, the undefined far field distribution of most commercially available high power diode laser stacks states a major drawback of these devices. As single emitters and bars can fail during their lifetime, the near field distribution does not remain constant. To overcome these problems, the intensity distribution can be homogenized by a waveguide or by microoptic devices. The waveguide segments the far field distribution by several total internal reflections, and these segments are overlaid at the waveguide's exit surface. By the microoptic device, the near field is divided into beamlets which are overlaid by a field lens. Both approaches are presented, and realized systems are described