Tjelesne osobine sivog vuka (Canis lupus L.)

Svrha ovoga rada je dobivanje prosječnih vrijednosti tjelesnih mjera sivog vuka (Canis lupus L.) u Hrvatskoj s ciljem njihovog razlikovanja po pojedinim dobnim kategorijama. Na području Gorskog kotara, Like i Dalmacije sakupljana su tijela nađenih vukova stradalih od različitih uzroka. Mjereno je 23 tjelesnih parametara, a zbog spolnog dimorfizma kod mužjaka je mjereno 21 mjera, a kod ženki 20 mjera. Statističkom obradom tjelesnih mjera pokazano je da mužjaci za većinu mjera imaju veće vrijednost od ženki, to jest brže napreduju u rastu. Razlike između spolova postaju sve očitije s porastom dobi životinja, da bi u odraslih jedinki bile najveće. Masa, kao jedan od pokazatelja tjelesne razvijenosti, najveća je u zimskom periodu i za mužjake i za ženke zbog veće dostupnosti plijena, dok u ostatku godine ostvaruje lagani pad

Detrended Fluctuation Analysis in the prediction of type 2 diabetes mellitus in patients at risk: Model optimization and comparison with other metrics

[EN] Complexity analysis of glucose time series with Detrended Fluctuation Analysis (DFA) has been proved to be useful for the prediction of type 2 diabetes mellitus (T2DM) development. We propose a modified DFA algorithm, review some of its characteristics and compare it with other metrics derived from continuous glucose monitorization in this setting. Several issues of the DFA algorithm were evaluated: (1) Time windowing: the best predictive value was obtained including all time-windows from 15 minutes to 24 hours. (2) Influence of circadian rhythms: for 48-hour glucometries, DFA alpha scaling exponent was calculated on 24hour sliding segments (1-hour gap, 23-hour overlap), with a median coefficient of variation of 3.2%, which suggests that analysing time series of at least 24-hour length avoids the influence of circadian rhythms. (3) Influence of pretreatment of the time series through integration: DFA without integration was more sensitive to the introduction of white noise and it showed significant predictive power to forecast the development of T2DM, while the pretreated time series did not. (4) Robustness of an interpolation algorithm for missing values: The modified DFA algorithm evaluates the percentage of missing values in a time series. Establishing a 2% error threshold, we estimated the number and length of missing segments that could be admitted to consider a time series as suitable for DFA analysis. For comparison with other metrics, a Principal Component Analysis was performed and the results neatly tease out four different components. The first vector carries information concerned with variability, the second represents mainly DFA alpha exponent, while the third and fourth vectors carry essentially information related to the two "pre-diabetic behaviours" (impaired fasting glucose and impaired glucose tolerance). The scaling exponent obtained with the modified DFA algorithm proposed has significant predictive power for the development of T2DM in a high-risk population compared with other variability metrics or with the standard DFA algorithm.This study has been funded by Instituto de Salud Carlos III through the project PI17/00856 (Co-funded by the European Regional Development Fund, A way to make Europe). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Colás, A.; Vigil, L.; Vargas, B.; Cuesta Frau, D.; Varela, M. (2019). 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Diabetologia, 53(3), 435-445. doi:10.1007/s00125-009-1614-2Nathan, D. M., Davidson, M. B., DeFronzo, R. A., Heine, R. J., Henry, R. R., Pratley, R., & Zinman, B. (2007). Impaired Fasting Glucose and Impaired Glucose Tolerance: Implications for care. Diabetes Care, 30(3), 753-759. doi:10.2337/dc07-9920Ogata, H., Tokuyama, K., Nagasaka, S., Tsuchita, T., Kusaka, I., Ishibashi, S., … Yamamoto, Y. (2012). The lack of long-range negative correlations in glucose dynamics is associated with worse glucose control in patients with diabetes mellitus. Metabolism, 61(7), 1041-1050. doi:10.1016/j.metabol.2011.12.007Kohnert, K.-D. (2015). Utility of different glycemic control metrics for optimizing management of diabetes. World Journal of Diabetes, 6(1), 17. doi:10.4239/wjd.v6.i1.17García Maset, L., González, L. B., Furquet, G. L., Suay, F. M., & Marco, R. H. (2016). Study of Glycemic Variability Through Time Series Analyses (Detrended Fluctuation Analysis and Poincaré Plot) in Children and Adolescents with Type 1 Diabetes. Diabetes Technology & Therapeutics, 18(11), 719-724. doi:10.1089/dia.2016.0208Service, F. J., O’Brien, P. C., & Rizza, R. A. (1987). Measurements of Glucose Control. Diabetes Care, 10(2), 225-237. doi:10.2337/diacare.10.2.225Goldberger, A. L., Amaral, L. A. N., Hausdorff, J. M., Ivanov, P. C., Peng, C.-K., & Stanley, H. E. (2002). Fractal dynamics in physiology: Alterations with disease and aging. Proceedings of the National Academy of Sciences, 99(Supplement 1), 2466-2472. doi:10.1073/pnas.012579499Crenier, L., Lytrivi, M., Van Dalem, A., Keymeulen, B., & Corvilain, B. (2016). Glucose Complexity Estimates Insulin Resistance in Either Nondiabetic Individuals or in Type 1 Diabetes. The Journal of Clinical Endocrinology & Metabolism, 101(4), 1490-1497. doi:10.1210/jc.2015-4035Rodríguez de Castro, C., Vigil, L., Vargas, B., García Delgado, E., García Carretero, R., Ruiz-Galiana, J., & Varela, M. (2016). Glucose time series complexity as a predictor of type 2 diabetes. Diabetes/Metabolism Research and Reviews, 33(2), e2831. doi:10.1002/dmrr.2831Weber, C., & Schnell, O. (2009). The Assessment of Glycemic Variability and Its Impact on Diabetes-Related Complications: An Overview. Diabetes Technology & Therapeutics, 11(10), 623-633. doi:10.1089/dia.2009.0043Pincus, S. M., Gladstone, I. M., & Ehrenkranz, R. A. (1991). A regularity statistic for medical data analysis. Journal of Clinical Monitoring, 7(4), 335-345. doi:10.1007/bf01619355Richman, J. S. (2007). Sample Entropy Statistics and Testing for Order in Complex Physiological Signals. Communications in Statistics - Theory and Methods, 36(5), 1005-1019. doi:10.1080/03610920601036481Platiša, M. 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Application of mathematical optimization in decision making relevant to the resilience of national security: Networked society as the basis of interdependence of critical resources

Introduction/purpose: Destabilization of critical resources (CRs) or critical infrastructure (CI) important for the stability of the state can be dangerous for society, economy, and especially national security. Disruption of one CI object or one of its parts often affects and causes disruption of other dependent CI, because the modern society has become a "networked society". The paper proposes a model for quantifying and defining the interdependence between different CIs and their priorities, based on statements of experts. Methods 9 : The proposed methods that combine the Laboratory for Testing and Evaluation of Decision Making (DEMATEL) and the Analytical Network Process (ANP) have been successfully modified by fuzzy logic theory in this work. Results: Integrating multiple methods into a unique input data analysis model significantly affects the change in ranking. Conclusion: The work contributes to military science in making strategic decisions related to national security management through increasing the resilience of CRs and the societies that rely on them

Electron-impact broadening parameters for Be II, Sr II, and Ba II spectral lines

Aims. We present results of the electron-impact broadening parameters (i.e., widths and shifts) of spectral lines in singly ionized Be II, Sr II, and Ba II ions, calculated by using our relativistic quantum mechanical methods. Methods. In these calculations, Dirac R-matrix methods were used to solve (N + 1)-electron colliding systems to obtain the required scattering matrices. The dimensionless collision strength Omega(epsilon) is calculated as a function of incident electron energies epsilon. Results. The present line-broadening parameters are required for future spectral analysis by means of state-of-the-art nonlocal thermodynamic equilibrium atmospheres, which is now hampered largely by the paucity of reliable atomic and accurate line-broadening data tables. Our results for the spectral line-broadening parameters in the case of three ions obtained for a set of electron temperatures at an electron density 10(17) cm(-3) show very good agreement with other theoretical calculations, and are much closer to the available experimental measurements.Astronomy & AstrophysicsSCI(E)EI2ARTICLEnull55