306 research outputs found

    Analysis of disease-related T cell receptors and their antigens in GABAA receptor encephalitis

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    Making design decisions under uncertainties: probabilistic reasoning and robust product design

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    Making design decisions is characterized by a high degree of uncertainty, especially in the early phase of the product development process, when little information is known, while the decisions made have an impact on the entire product life cycle. Therefore, the goal of complexity management is to reduce uncertainty in order to minimize or avoid the need for design changes in a late phase of product development or in the use phase. With our approach we model the uncertainties with probabilistic reasoning in a Bayesian decision network explicitly, as the uncertainties are directly attached to parts of the design artifact′s model. By modeling the incomplete information expressed by unobserved variables in the Bayesian network in terms of probabilities, as well as the variation of product properties or parameters, a conclusion about the robustness of the product can be made. The application example of a rotary valve from engineering design shows that the decision network can support the engineer in decision-making under uncertainty. Furthermore, a contribution to knowledge formalization in the development project is made

    Patron-Driven Acquisition (PDA) - ein Modell mit Zukunft?

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    Gestützt auf eine dreijährige Erfahrung mit der nutzergesteuerten Erwerbung an der UB Erlangen-Nürnberg beleuchtet der Beitrag die verschiedenen Rollen der an dieser Erwerbungsform beteiligten Akteure. Vor dem Hintergrund geänderter Geschäftsmodelle werden die zukünftigen Perspektiven der nutzergesteuerten Erwerbung in Deutschland kritisch hinterfragt. Based on a three years experience with Patron-Driven Acquisition at University library Erlangen-Nuremberg the article discusses the roles of the protagonists at this acquisition form. Regarding to modified business models the perspectives of Patron-Driven Acquision in Germany seems to be unconfident.

    Neuer Vorstand des VDB Landesverband Bayern

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