PENYULUHAN TENTANG PENERAPAN ROLL O’PACK DI RUANG PENYIMPANAN REKAM MEDIS DI RUMAH SAKIT UMUM SEMBIRING

The confidentiality of the contents of medical records is strengthened by the Republic of Indonesia Minister of Health Regulation No. 269 / Menkes / Per / III / 2008 article 10 paragraph 1 which states  "Information  about  the  identity,  diagnosis,  medical  history,  examination  history  and treatment  history  of  the patient  must  be  kept  confidential by doctors,  dentists,  certain  health workers, management officers and leaders of service facilities. Health ”The medical record file storage system in public hospitals while using a centralized management system where outpatient and inpatient medical record files become one. The storage device uses an open wooden shelf. According to the Ministry of Health, RI (1991) in Ahmadi (2011: 16), that the medical record file storage room must pay attention to the following matters: The medical record storage room should be separated from other office rooms to maintain the safety of these medical records. Roll O Pack is a Push Filing cabinet for storing large capacity documents that can be moved manually or by mechanical drive. The results showed that before conducting counseling, the officers did not know the advantages and disadvantages of using the o'pack roll, before implementing the o'pack roll at the RSU Sembiring, the officer had to know first what the advantages and disadvantages of the o'pack roll were, if the o'pack roll gave more There are many advantages for officers and services, so the implementation of roll o'pack is very much needed and must be realized as soon as possible so that the storage system at the RSU Sembiring becomes rapid and the files are not damaged so that the useful value of medical record files is better

Photon shot-noise limited transient absorption soft X-ray spectroscopy at the European XFEL

Femtosecond transient soft X-ray Absorption Spectroscopy (XAS) is a very promising technique that can be employed at X-ray Free Electron Lasers (FELs) to investigate out-of-equilibrium dynamics for material and energy research. Here we present a dedicated setup for soft X-rays available at the Spectroscopy & Coherent Scattering (SCS) instrument at the European X-ray Free Electron Laser (EuXFEL). It consists of a beam-splitting off-axis zone plate (BOZ) used in transmission to create three copies of the incoming beam, which are used to measure the transmitted intensity through the excited and unexcited sample, as well as to monitor the incoming intensity. Since these three intensity signals are detected shot-by-shot and simultaneously, this setup allows normalized shot-by-shot analysis of the transmission. For photon detection, the DSSC imaging detector, which is capable of recording up to 800 images at 4.5 MHz frame rate during the FEL burst, is employed and allows approaching the photon shot-noise limit. We review the setup and its capabilities, as well as the online and offline analysis tools provided to users.Comment: 11 figure

The Helsinki bike‐sharing system—Insights gained from a spatiotemporal functional model

Understanding the usage patterns for bike-sharing systems is essential in terms of supporting and enhancing operational planning for such schemes. Studies have demonstrated how factors such as weather conditions influence the number of bikes that should be available at bike-sharing stations at certain times during the day. However, the influences of these factors usually vary over the course of a day, and if there is good temporal resolution, there could also be significant effects only for some hours/minutes (rush hours, the hours when shops are open and so forth). Thus, in this paper, an analysis of Helsinki's bike-sharing data from 2017 is conducted that considers full temporal and spatial resolutions. The station hire data are analysed in a spatiotemporal functional setting, where the number of bikes at a station is defined as a continuous function of the time of day. For this completely novel approach, we apply a functional spatiotemporal hierarchical model to investigate the effect of environmental factors and the magnitude of the spatial and temporal dependence. Challenges in computational complexity are faced using a Monte Carlo subsampling approach. The results show the necessity of splitting the bike-sharing stations into two clusters based on the similarity of their spatiotemporal functional observations in order to model the station hire data of Helsinki's bike-sharing system effectively

Characterization and treatment of persistent hepatocellular secretory failure

Hepatocellular secretory failure induced by drugs, toxins or transient biliary obstruction may sometimes persist for months after removal of the initiating factor and may then be fatal without liver transplantation. We characterized patients with severe persistent hepatocellular secretory failure (PHSF) and treated them with the pregnane X receptor (PXR) agonist, rifampicin. We also studied the effect of rifampicin on PXR-dependent expression of genes involved in biotransformation and secretion in vitro. Thirteen patients (age 18-81 years, 6 male) with hepatocellular secretory failure that persisted after removal of the inducing factor (drugs/toxin: 9) or biliary obstruction (4) were identified over 6 years. Six of these patients were screened for ATP8B1 or ABCB11 mutations. All were treated with rifampicin (300 mg daily) for 1-10 weeks. Expression of genes involved in biotransformation and secretion was determined by rtPCR in human hepatocytes and intestinal cells incubated with rifampicin (10 μmol/L). Serum bilirubin of patients with PHSF ranged from 264 to 755 μmol/L. Normal γGT was found in 10/13 patients of whom 3/6 tested positive for ATP8B1/ABCB11 mutations. Serum bilirubin declined to <33 μmol/L after 1-10 weeks of rifampicin treatment. In vitro, rifampicin PXR-dependently upregulated biotransformation phase 1 (CYP3A4), phase 2 (UGT1A1) and phase 3 (MRP2) enzymes/carriers as well as the basolateral bile salt exporter OSTβ. Persistent hepatocellular secretory failure may develop in carriers of transporter gene mutations. In severe cases, rifampicin may represent an effective therapeutic option of PHSF. PXR-dependent induction of CYP3A4, UGT1A1, MRP2 and OSTβ could contribute to the anticholestatic effect of rifampicin in PHS

Electron Population Dynamics in Resonant Non-Linear X-ray Absorption in Nickel at a Free-Electron Laser

Free-electron lasers provide bright, ultrashort, and monochromatic X-ray pulses, enabling novel spectroscopic mea-surements not only with femtosecond temporal resolution: The high fluence of their X-ray pulses can also easily enterthe regime of non-linear X-ray-matter interaction. Entering this regime necessitates a rigorous analysis and reliableprediction of the relevant non-linear processes for future experiment designs. Here we show non-linear changes in theL3-edge absorption of metallic nickel thin films, measured with fluences up to 60 J/cm2. We present a simple but pre-dictive rate model that quantitatively describes spectral changes based on the evolution of electronic populations withinthe pulse duration. Despite its simplicity, the model reaches good agreement with experimental results over more thanthree orders of magnitude in fluence, while providing a straightforward understanding of the interplay of physical pro-cesses driving the non-linear changes. Our findings provide important insights for the design and evaluation of futurehigh-fluence free-electron laser experiments, and contribute to the understanding of non-linear electron dynamics inX-ray absorption processes in solids at the femtosecond timescale

Electron Dynamics at High-Energy Densities in Nickel from Non-linear Resonant X-ray Absorption Spectra

The pulse intensity from X-ray free-electron lasers (FELs) can create extreme excitation densities in solids, entering the regime of non-linear X-ray-matter interactions. We show L3-edge absorption spectra of metallic nickel thin films with fluences entering a regime where several X-ray photons are incident per absorption cross-section. Main features of the observed non-linear spectral changes are described with a predictive rate model for electron population dynamics during the pulse, utilizing a fixed density of states and tabulated ground-state properties

The interplay of local electron correlations and ultrafast spin dynamics in fcc Ni

The complex electronic structure of metallic ferromagnets is determined by a balance between exchange interaction, electron hopping leading to band formation, and local Coulomb repulsion. By combining high energy and temporal resolution in femtosecond time-resolved X-ray absorption spectroscopy with ab initio time-dependent density functional theory we analyze the electronic structure in fcc Ni on the time scale of these interactions in a pump-probe experiment. We distinguish transient broadening and energy shifts in the absorption spectra, which we demonstrate to be captured by electron repopulation respectively correlation-induced modifications of the electronic structure, requiring to take the local Coulomb interaction into account