Estudo de dieta total piloto para avaliação da ingestão de nutrientes e da exposição a contaminantes: amostragem

Objetivo: Realização de um TDS piloto que visa implementar as metodologias harmonizadas a nível europeu no âmbito do projeto TDS_EXPOSURE. No presente trabalho descreve-se a metodologia para definição da amostragem do estudo, recolha e preparação das amostras e respetivos resultados.A realização deste estudo foi parcialmente financiada pelo 7º Programa Quadro da União Europeia para investigação, desenvolvimento tecnológico e demonstração (Grant agreement n°289108)

Management of asthma in childhood: study protocol of a systematic evidence update by the Paediatric Asthma in Real Life (PeARL) Think Tank

IntroductionClinical recommendations for childhood asthma are often based on data extrapolated from studies conducted in adults, despite significant differences in mechanisms and response to treatments. The Paediatric Asthma in Real Life (PeARL) Think Tank aspires to develop recommendations based on the best available evidence from studies in children. An overview of systematic reviews (SRs) on paediatric asthma maintenance management and an SR of treatments for acute asthma attacks in children, requiring an emergency presentation with/without hospital admission will be conducted.Methods and analysisStandard methodology recommended by Cochrane will be followed. Maintenance pharmacotherapy of childhood asthma will be evaluated in an overview of SRs published after 2005 and including clinical trials or real-life studies. For evaluating pharmacotherapy of acute asthma attacks leading to an emergency presentation with/without hospital admission, we opted to conduct de novo synthesis in the absence of adequate up-to-date published SRs. For the SR of acute asthma pharmacotherapy, we will consider eligible SRs, clinical trials or real-life studies without time restrictions. Our evidence updates will be based on broad searches of Pubmed/Medline and the Cochrane Library. We will use A MeaSurement Tool to Assess systematic Reviews, V.2, Cochrane risk of bias 2 and REal Life EVidence AssessmeNt Tool to evaluate the methodological quality of SRs, controlled clinical trials and real-life studies, respectively. Next, we will further assess interventions for acute severe asthma attacks with positive clinical results in meta-analyses. We will include both controlled clinical trials and observational studies and will assess their quality using the previously mentioned tools. We will employ random effect models for conducting meta-analyses, and Grading of Recommendations Assessment, Development and Evaluation methodology to assess certainty in the body of evidence.Ethics and disseminationEthics approval is not required for SRs. Our findings will be published in peer reviewed journals and will inform clinical recommendations being developed by the PeARL Think Tank.PROSPERO registration numbers CRD42020132990, CRD42020171624.</p

Introdução aos Estudos de Dieta Total - Apresentação do Projecto TDSExposure

Definição Estudo de Dieta Total (TDS-Total Diet Studies); Introdução aos Estudos TDS; Apresentação Projeto TDSExposure; Trabalhos a decorrer no INSA no âmbito do projeto7thFP E

Validação de um método alternativo de análise de glúten em géneros alimentícios, o ELISA-R5 : comparação com o método oficial de análise

Tese de mestrado em Controlo da Qualidade e Toxicologia dos Alimentos apresentada à Universidade de Lisboa através da Faculdade de Farmácia, 200

Practical experience with TDS pilot study in the Portugal

FP7 - This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration (Grant Agreement no. 289108

TASK 9.9 Quality management practices: SOPs – results

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WP 9.3 Description of kitchen preparations to be used for food cooking

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D5.4 Report including list of SOPs required and quality control and quality assurance activities.

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WP 9.3 Description of kitchen preparations to be used for food cooking

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Sub-task 5.2.1: Overall framework of TDS Processes. D5.3 Generic flowcharts and interrelations with CCPs and Indicator

FP7 - This project has received funding from the European Union’s Seventh Framework Programme for research, technological development and demonstration (Grant Agreement no. 289108